Prenatal and perinatal risk factors for Tourette disorder
-
L. Burd
Abstract
Aims: To identify pre- and perinatal risk factors for Tourette disorder.
Methods: Case control study. We matched names of patients who met DSM criteria for Tourette disorder with their birth certificates. For each case five controls were selected. The controls were matched by sex, year and month of birth.
Results: Univariate analysis of the 92 cases and the 460 matched controls identified 4 risk factors; one categorical variable–trimester prenatal care begun and 3 continuous variables 2 apgar score at 5 minutes, month prenatal began and number of prenatal visits. Logistic modeling to control for confounding produced a three variable model (apgar score at 5 minutes (OR 5 1.31), number of prenatal visits (OR 5 .904) and fathers age (OR 5 .909). The model parameters were: χ2 5 19.76; df 5 3; p < .001.
Conclusions: This is an inexpensive methodology to identify potential risk factors of patients with Tourette disorder and other mental illness.
Copyright (c)1999 by Walter de Gruyter GmbH & Co. KG
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Artikel in diesem Heft
- Measurement of the amniotic fluid index with and without Color Doppler
- Comparison of delayed absorbable suture v nonabsorbable suture for treatment of incompetent cervix
- Intra amniotic candidiasis. Case report and meta-analysis of 54 cases
- Factors relating to readmission of term and near term neonates in the first two weeks of life
- Congenital diaphragmatic hernia: Atypical presentation
- Real-time optical imaging of experimental brain ischemia and hemorrhage in neonatal piglets
- Ventricular dominance patterns in preterm infants
- One day old infant with acyanotic congenital heart disease: critical aortic stenosis
- Prenatal and perinatal risk factors for Tourette disorder
- The diagnostic role of "in utero” magnetic resonance imaging
- Effect of dexamethasone, triiodothyronine and dimethyl-isopropyl-thyronine on lung maturation of the fetal rat lung
- Yolk sac size and shape as predictors of poor pregnancy outcome
