Chapters in this book

1. Frontmatter I
2. CONTENTS V
3. Acknowledgments XI
4. Introduction XIII
5. Part One. The Normal Pulmonary and Bronchial Circulations
6. 1. The Normal Pulmonary Microcirculation 3
7. 2. Comparative Biology of the Pulmonary Circulation 17
8. 3. Excitation and Contraction in Smooth Muscle 31
9. 4. Pulmonary Vascular Resistance (P:Q Relations) 41
10. 5. Endothelial and Smooth Muscle Cell Interaction 57
11. 6. Endothelial Processing of Biologically Active Materials 69
12. 7. Endothelin: Mediator of Hypoxic Vasoconstriction? 85
13. 8. Mediators in the Pulmonary Circulation 91
14. 9. The Enigma of Hypoxic Pulmonary Vasoconstriction 109
15. 10. Central Neural Regulation of the Pulmonary Circulation 131
16. 11. Bronchial Circulation 151
17. 12. Tone and Responsiveness in the Fetal and Neonatal Pulmonary Circulation 161
18. Part Two. Vascular Injury
19. 13. Endothelial Injury Studied in Cell Culture 173
20. 14. Inhibition of Proliferation of Vascular Smooth Muscle Cells by Heparin 187
21. 15. Role of Growth Factors in Pulmonary Hypertension 201
22. 16. Oxygen Radicals and Vascular Injury 217
23. 17. Endothelial Cell Modulation of Coagulation and Fibrinolysis 231
24. 18. Atherogenesis in the Pulmonary Artery 245
25. Part Three. Pulmonary Hypertension
26. 19. Vascular Remodeling 259
27. 20. Chronic Hypoxic Pulmonary Hypertension 283
28. 21. Familial Pulmonary Hypertension 301
29. 22. Animal Models of Chronic Pulmonary Hypertension 315
30. 23. The Pathology of Secondary Pulmonary Hypertension 329
31. 24. Pulmonary Veno-Occlusive Disease 343
32. 25. Pulmonary Hypertension in Collagen Vascular Disease 353
33. 26. Pulmonary Hypertension Associated with Hepatic Cirrhosis 359
34. 27. Persistent Pulmonary Hypertension of the Newborn 371
35. 28. Pulmonary Hypertension in the Toxic Oil Syndrome 385
36. 29. Amiriorex Pulmonary Hypertension 397
37. 30. Thromboembolic Pulmonary Hypertension 413
38. Part Four. The Primary Pulmonary Hypertension Registry
39. 31. Introduction to the National Registry on Primary Pulmonary Hypertension 437
40. 32. The Research and Clinical Dilemmas Encountered by the Primary Pulmonary Hypertension Registry 441
41. 33. NIH Registry on Primary Pulmonary Hypertension: Baseline Characteristics of the Patients Enrolled 451
42. 34. The Histopathology of Primary Pulmonary Hypertension 459
43. 35. Mortality Follow-Up of Primary Pulmonary Hypertension 473
44. Part Five. Treatment of Pulmonary Hypertension
45. 36. Vasodilator Therapy (General Aspects) 479
46. 37. Acute Vasodilator Testing and Pharmacological Treatment of Primary Pulmonary Hypertension 485
47. 38. Anticoagulation in the Treatment of Pulmonary Hypertension 501
48. 39. The Criteria and Preparation for Heart-Lung Transplantation 511
49. Contributors 523
50. Index 529