PAPER PHYSICS. Paper-based device for pre-concentration of target analytes
-
Vincent Leung
und
Carlos D. M. Filipe
Abstract
In this paper, we demoostrate proof-ofprinciple for a low cost paper-based Chromatographie device capable of pre-concentrating a target analyte by a factor of three thousand fold (assessed using confocal Iaser scanning microscopy (LSCM)). The device consists of a capture zone and a passive pump. The capture zone was created by immobilizing biotinylated microgel particles onto a selected area of filter paper. Due to the presence of biotin on their surface, these particles have the ability to specifically bind streptavidin, which was the target analyte selected for this study. With the incorporation of a superabsorbent passive pump, created using cross-linked poly(acrylic acid), partial sodium saltgra. fi-poly(ethylene oxide), the paper-based device was able to process a volume of dilute solution much larger than that associated with paper porosity. Flow through the device, including the passive pump, could be modeled using Darcy' s law. A simple equation was also developed to relate the concentration in the pre-concentration device to the concentration in the dilute sample. This type of device can be useful for sample pre-concentration before analysis using other methods, such as mass spectrometry.
© 2018 by Walter de Gruyter Berlin/Boston
Artikel in diesem Heft
- Contents
- BIOREFINERY. Pressurised hot water extraction of acetylated xylan from birch sawdust
- BIOREFINERY. Nanocellulose characterization with mechanical fractionation
- MECHANICAL PULPING.Analysis method of high-consistency chip refiner forces
- MECHANICAL PULPING.Effect of long fibre concentration on low consistency refining of mechanical pulp
- CHEMICAL PULPING. Oxidative degradation of AOX in softwood-based kraft mill effluents from E C F bleachin g
- COATING. lnfluence of the distribution of the shape and size distribution of pigment particles on cracking in coating layers during creasin
- PRINTING.Natural zeolite as filler in base ink jet paper sheet
- PRINTING.Paper and printer effects on xerographic print quality
- PRINTING. The ageing resistance of offset and electrophotographic prints
- PAPER INK INTERACTIONS. The effect of coating pore structure and geometry on the drying efficiency of heatset web-offset ink solvent
- PAPER INK INTERACTIONS. Impact of oil-binder interaction on pore structure in paper coating as studied by internal reflectance Part 1 : implications of pore volume loss for print drying
- PAPER INK INTERACTIONS .Impact of oil-binder interaction on pore structure in paper coatings as studied by internal reflectance. Part 2: Relation to structural expansion
- PAPER PHYSICS. Bi-level optimization in papermaking process design
- PAPER PHYSICS. PIV measurements of flow through forming fabrics
- PAPER PHYSICS .The effect of newsprint furnish composition and sheet structure on wet pressing efficiency
- PAPER PHYSICS. The web structure in relation to the furnish composition and shoe press pulse profiles during wet pressing
- PAPER PHYSICS. Analytical Prediction of Package Collapse Loads-Basic considerations
- PAPER PHYSICS. Paper-based device for pre-concentration of target analytes
Artikel in diesem Heft
- Contents
- BIOREFINERY. Pressurised hot water extraction of acetylated xylan from birch sawdust
- BIOREFINERY. Nanocellulose characterization with mechanical fractionation
- MECHANICAL PULPING.Analysis method of high-consistency chip refiner forces
- MECHANICAL PULPING.Effect of long fibre concentration on low consistency refining of mechanical pulp
- CHEMICAL PULPING. Oxidative degradation of AOX in softwood-based kraft mill effluents from E C F bleachin g
- COATING. lnfluence of the distribution of the shape and size distribution of pigment particles on cracking in coating layers during creasin
- PRINTING.Natural zeolite as filler in base ink jet paper sheet
- PRINTING.Paper and printer effects on xerographic print quality
- PRINTING. The ageing resistance of offset and electrophotographic prints
- PAPER INK INTERACTIONS. The effect of coating pore structure and geometry on the drying efficiency of heatset web-offset ink solvent
- PAPER INK INTERACTIONS. Impact of oil-binder interaction on pore structure in paper coating as studied by internal reflectance Part 1 : implications of pore volume loss for print drying
- PAPER INK INTERACTIONS .Impact of oil-binder interaction on pore structure in paper coatings as studied by internal reflectance. Part 2: Relation to structural expansion
- PAPER PHYSICS. Bi-level optimization in papermaking process design
- PAPER PHYSICS. PIV measurements of flow through forming fabrics
- PAPER PHYSICS .The effect of newsprint furnish composition and sheet structure on wet pressing efficiency
- PAPER PHYSICS. The web structure in relation to the furnish composition and shoe press pulse profiles during wet pressing
- PAPER PHYSICS. Analytical Prediction of Package Collapse Loads-Basic considerations
- PAPER PHYSICS. Paper-based device for pre-concentration of target analytes
