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The sweet coat of living cells – from supramolecular structure and dynamics to biological function

  • Natalia S. Baranova , Seetharamaiah Attili , Patricia M. Wolny and Ralf P. Richter
Published/Copyright: June 11, 2013
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International Journal of Materials Research
From the journal International Journal of Materials Research Volume 102 Issue 7

Abstract

Many biological cells endow themselves with a sugar-rich coat that plays a key role in the protection of the cell and in structuring and communicating with its environment. An outstanding property of these pericellular coats is their dynamic self-organization into strongly hydrated and gel-like meshworks. Tailor-made model systems that are constructed from the molecular building blocks of pericellular coats can help to understand how the coats function. The creation and investigation of such model systems requires a tight interplay between established biochemical methods and unconventional approaches from the fields of biophysics, polymer physics, and surface and material sciences.

Keywords: Pericellular coat; Hyaluronan; Surface-sensitive in-situ characterization techniques; Hydrogel; Supramolecular self-organization
* Correspondence address PhD Ralf Richter CIC biomaGUNE, Biosurfaces Unit Paseo Miramon 182, 20009 San Sebastian, Spain Tel.: +34 943 00 53 29 Fax: +34 943 00 53 15 E-mail:

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Received: 2011-1-27
Accepted: 2011-4-15
Published Online: 2013-06-11
Published in Print: 2011-07-01

© 2011, Carl Hanser Verlag, München

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https://doi.org/10.3139/146.110534
Keywords for this article
Pericellular coat; Hyaluronan; Surface-sensitive in-situ characterization techniques; Hydrogel; Supramolecular self-organization

Articles in the same Issue

  1. Contents
  2. Contents
  3. Editorial
  4. Max Planck Institute for Metals Research – 90 Years of Excellence in Materials Science
  5. Words of Welcome
  6. Words of Welcome
  7. Feature
  8. Magnetism studied with circularly polarized X-rays
  9. Solid state phase transformation kinetics: Evaluation of the modular transformation model
  10. Intelligent induction of active biosystem responses at interfaces
  11. Empirical Inference
  12. The Stuttgart Center for Electron Microscopy at the Max Planck Institute for Metals Research
  13. The filamentary growth of metals
  14. Kinetics of interface-controlled phase transformations: atomistic and mesoscopic simulations
  15. Breakthroughs in understanding elastic grain interaction and whisker formation made possible by advances in X-ray powder diffraction
  16. Ordered and disordered states in NiAs/Ni2In-type Ni1+δSn: Crystallography and order formation
  17. Of fluctuations and cross-correlations: finding order in disorder
  18. Experimental characterization of tumor spheroids for studies of the energetics of tumor growth
  19. Soft lithography detects partial mechano-sensoric blindness to micrometre topography in cultured aged and diseased cells
  20. The sweet coat of living cells – from supramolecular structure and dynamics to biological function
  21. Nonlinear spectroscopy of bio-interfaces
  22. Dedicated beamlines for in-situ investigations of materials in reduced dimensions
  23. People
  24. Laudationes
  25. Review
  26. Book review
  27. DGM News
  28. DGM News
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