Startseite Modelling study on production cross sections of 111In radioisotopes used in nuclear medicine
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Modelling study on production cross sections of 111In radioisotopes used in nuclear medicine

  • A. Kara , T. Korkut , M. Yiğit und E. Tel
Veröffentlicht/Copyright: 26. Juni 2015
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Abstract

Radiopharmaceuticals are radioactive drugs used for diagnosis or treatment in a tracer quantity with no pharmacological action. The production of radiopharmaceuticals is carried out in the special research centers generally using by the cyclotron systems. Indium-111 is one of the most useful radioisotopes used in nuclear medicine. In this paper, we calculated the production cross sections of 111In radioisotope via 111–114Cd(p,xn) nuclear reactions up to 60 MeV energy. In the model calculations, ALICE/ASH, TALYS 1.6 and EMPIRE 3.2 Malta nuclear reaction code systems were used. The model calculation results were compared to the experimental literature data and TENDL-2014 (TALYS-based) data.

Kurzfassung

Radiopharmazeutika sind Arzneimittel, die Radionuklide enthalten, deren Strahlung diagnostisch oder therapeutisch in genutzt wird. Die Herstellung von Radiopharmazeutika erfolgt in speziellen Forschungszentren, meist mit Hilfe eines Zyklotrons. Indium-111 ist eines der am meisten genutzten Radionuklide in der Nuklearmedizin. In diesem Beitrag wurden die Produktionsquerschnitte von 111In-Radionukliden via 111–114Cd(p,xn)-Kernreaktionen mit einer Energie von bis zu 60 MeV berechnet. Bei den Modellrechnungen wurden ALICE/ASH, TALYS 1.6 und EMPIRE 3.2 Malta Kernreaktionsrechensysteme verwendet. Die Ergebnisse der Modellrechnungen wurden verglichen mit experimentellen Daten aus der Literatur und TENDL-2014 (TALYS-based) Daten.


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Received: 2015-02-15
Published Online: 2015-06-26
Published in Print: 2015-07-25

© 2015, Carl Hanser Verlag, München

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