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Synthesis of Some Novel Sulfonamide Derivatives and Investigating their Biocidal Activity in Cooling Towers

  • A. M. Badawi , D. E. Mohamed , A. A. Hafiz , S. M. Ahmed , Y. M. Gohar , E. A. Soliman and M. S. A. Sanan
Published/Copyright: April 11, 2013
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Tenside Surfactants Detergents
From the journal Tenside Surfactants Detergents Volume 48 Issue 2

Abstract

A novel series of dibenzothiophenedioxide sulphonamide derivatives were synthesized and tested as antimicrobial agents. The chemical structures of the prepared compounds were confirmed by micro elemental analysis, fourier transform infrared (FT-IR) and proton nuclear magnetic resonance spectroscopy (H-NMR). The surface parameters of two of the prepared compounds were determined at 35°C including, surface tension, effectiveness, maximum surface excess and minimum surface area. Also the standard free energy of micellization and adsorption were recorded. The results showed that the prepared sulphonamides have good surface properties and effective antimicrobial activity against thirty three test organisms isolated from cooling towers.

Kurzfassung

Eine Reihe neuer Dibenzothiophensulfonamid-Derivate wurde synthetisiert. Die Eignung der Derivate als antimikrobielle Mittel wurde getestet. Die chemischen Strukturen der hergestellten Verbindungen wurde mit Hilfe von Mikroelementaranalyse, Fourier-Transform-Infrarot- (FT-IR) und Kernmagnetische Resonanzspektroskopie (H-NMR) bestätigt. Die Oberflächenparameter (Oberflächenspannung, Wirkungsgrad, maximaler Oberflächenüberschuss und minimaler Oberflächenplatzbedarf) von zwei der synthetisierten Verbindungen wurden bei 35°C bestimmt. Auch die freie Gibbs-Energie der Mizellenbildung und die Adsorption wurden bestimmt. Die Ergebnisse machen deutlich, dass die synthetisierten Sulfonamide gute Oberflächeneigenschaften und eine hohe antimikrobielle Aktivität gegen dreiunddreißig Testorganismen haben, die aus Kühltürmen isoliert wurden.

Key words:: Sulphonamides; antimicrobial agents; cooling towers; surface activity
Stichwörter:: Sulfonamide; antimikrobielle Mittel; Kühltürme; Oberflächenaktivität
∗ Dr. Dalia Emam Mohamed, Applied Surfactants Laboratory, Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo, Egypt. E-Mail:

Abdelfattah M. Badawi received his Ph.D. in applied organic chemistry from Al-Azhar University. He has completed courses on chemical warfare agent verification at Helsinki University (Finland) and at the Institute for Applied Surfactant Research from the University of Oklahoma. Presently, he is a professor of applied organic chemistry at the Egyptian Petroleum Research Institute.

Dalia Emam Mohamed is a researcher at the Egyptian Petroleum Research Institute (Surfactants Laboratory). She received a M.Sc. from Cairo University (2004) and a Ph.D. from Ain Shams University (2007). Her research interests are in synthesis, properties and applications of new surfactants.

Amal A. Hafiz received a M.Sc. in organic chemistry (1992) and a Ph.D. in applied organic chemistry (1997) from Ain Shams University. She has been Associate Professor at the Egyptian Petroleum Research Institute (Surfactants Laboratory) since 2003. She has published several research papers in international journals on the synthesis and application of new surface active agents and has supervised M.Sc. and Ph.D. theses on applied surfactants and environmental chemistry.

Sahar M. Ahmed is a Professor at the Egyptian Petroleum Research Institute (Surfactants Laboratory). She has published several research papers in international journals in the surfactants field.

Yousry M. Gohar is a Professor at Faculty of Science, Botany Department, Microbiology Section, Alexandria University.

El-Sayed Ahmed Soliman received his Ph.D. in organic chemistry from Ain Shams University in 1974. He has been Head of the Chemistry Department at Ain Shams University since 2006, as well as a Professor in Houria Boume'diene University for Science and Technology, Institute of Chemistry, Algeria, from 1986 to 1990.

Mohamed S. Sanan is a chemist at Alexandria National Refining & Petrochemical Co. (ANRPC), Alex., Egypt.

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Received: 2010-09-14
Published Online: 2013-04-11
Published in Print: 2011-03-01

© 2011, Carl Hanser Publisher, Munich

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https://doi.org/10.3139/113.110117
Keywords for this article
Sulphonamides; antimicrobial agents; cooling towers; surface activity

Articles in the same Issue

  1. Contents/Inhalt
  2. Contents
  3. Abstracts
  4. Abstracts
  5. Application
  6. Alkyl Polyglycoside/1-Naphthol Formulations: A Case Study of Surfactant Enhanced Oil Recovery
  7. 5-(3-Bromo-4-hydroxy-5-methoxyphenyl)-7,7-dimethyl-7H-indolo[1,2-a]quinolinium Perchlorate as a New Indicator for Anionic Surface Active Agents Determination
  8. Environmental Chemistry
  9. Kinetics and Adsorption Isotherms for the Removal of Tartrazine from Aqueous Solution by Coal Ash
  10. Removal of Triphenylmethane Dye from Aqueous Solution by Carbonaceous Adsorbent
  11. European Detergents Conference
  12. Nonequilibrium Association of Oppositely Charged Macromolecules and Amphiphiles
  13. Novel Surfactants
  14. Syntheses and Properties of New Double-tail Trisiloxane Surfactants with Both Hydrolysis Resistance and High Spreading Ability
  15. Synthesis of Some Novel Sulfonamide Derivatives and Investigating their Biocidal Activity in Cooling Towers
  16. Physical Chemistry
  17. Micellar Characteristics and Surface Properties of Some Sulfobetaine Surfactants
  18. Viscosity and Percolative Phenomena in AOT based Microemulsions
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