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Bone-Bio Material Interface
-
J.E. Davies
Language:
English
Published/Copyright:
1991
About this book
Topics of the papers include current understanding of the influence of materials surfaces on bone generation; bone cell response to materials; molecular biological probes to study the interface; mechanical influence on interfacial biology; and retrieval analysis for interpreting interfacial phenomena.
Author / Editor information
Davies J.E. :
J.E. Davies is Head of the Bone Cell/Biomaterials Research Group and an Associate Professor with the Centre for Biomaterials at the University of Toronto.
Topics
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Frontmatter
i -
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Contents
v -
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Foreword
ix -
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Preface
xi -
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Acknowledgments
xiii - Part 1: The Material Surface
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1. Surface Characterization of Implant Materials: Biological Implications
3 -
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2. The Biomaterial-Tissue Interface and Its Analogues in Surface Science and Technology
19 -
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3. Surface Reaction Kinetics and Adsorption of Biological Moieties: A Mechanistic Approach to Tissue Attachment
33 -
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4. Titanium and Its Oxide Film: A Substrate for Formation of Apatite
49 -
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5. Titanium: Immersion-Induced Surface Chemistry Changes and the Relationship to Passive Dissolution and Bioactivity
62 -
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6. Kinetics of Mineralization, Demineralization, and Transformation of Calcium Phosphates at Mineral and Protein Surfaces
68 -
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7. Substrate Surface Dissolution and Interfacial Biological Mineralization
76 -
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8. High-Resolution Electron Microscopy of a Bone Implant Interface
89 - Part 2: Bone Proteins and Other Macromolecules
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9. Non-Collagenous Bone Proteins and Their Role in Substrate-Induced Bioactivity
97 -
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10. Role of Adhesive Proteins and Integrins in Bone and Ligament Cell Behavior at the Material Surface
111 -
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11. Non-Endocrine Regulation of Bone Cell Activity
120 -
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12. Osteogenesis Induced by BMP-Coated Biomaterials: Biochemical Principles of Bone Reconstruction in Dentistry
127 -
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13. Ceramic Synthesis using Biological Processes
139 -
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Parts 1 and 2 - General Discussion
147 - Part 3: Cellular Activity at the Interface
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14. Inflammatory Cell Response to Bone Implant Surfaces
153 -
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15. Modulation of Cell Activity by Titanium Peroxy Compounds
165 -
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16. Behaviour of Osteoblasts on Micromachined Surfaces
170 -
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17. Osteoblast Reactions to Charged Polymers
181 -
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18. Cell-Mediated Bone Regeneration
199 -
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19. The Influence of Sputtered Bone Substitutes on Cell Growth and Phenotypic Expression
205 -
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20. Early Extracellular Matrix Synthesis by Bone Cells
214 -
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21. Transmission Electron Microscopical Identification of Extracellular Matrix Components using Immunocytochemistry
229 -
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22. Molecular Biological Approaches to Investigate Cell/Biomaterial Interactions
241 -
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23. Biological Cascades of Fracture Healing as Models for Bone-Biomaterial Interfacial Reactions
250 -
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24. Tissue Responses to Bone-Derived and Synthetic Materials
265 -
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25. Hard and Soft Connective Tissue Growth and Repair in Response to Charged Surfaces
275 -
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26. Deposition of Cement-like Matrix on Implant Materials
285 -
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27. Polymer Reactions Resulting in Bone Bonding: A Review of the Biocompatibility of Polyactive
295 -
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28. Comparative Morphology of the Bone Interface with Glass Ceramics, Hydroxyapatite, and Natural Coral
308 -
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29. Interfacial Reactions to Bioactive and Non-bioactive Bone Cements
321 -
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30. Modulation of Bone Ingrowth by Surface Chemistry and Roughness
334 -
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31. Comparative Push-out Data of Bioactive and Non-bioactive Materials of Similar Rugosity
350 -
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32. Quantified Bone Tissue Reactions to Various Metallic Materials with Reference to the So-called Osseointegration Concept
357 - Part 5: Mechanical Effects on Interfacial Biology
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33. Effect of Mechanical Stress on Tissue Differentiation in the Bony Implant Bed
367 -
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34. Quantitative Evaluation of the Effect of Movement at a Porous Coated Implant-Bone Interface
380 -
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35. Bone Ingrowth into Porous Coatings Attached to Prostheses of Differing Stiffness
388 -
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36. Influence of Biomechanical Factors at the Bone-Biomaterial Interface
391 -
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37. Bone Bonding Behavior of Biomaterials with Different Surface Characteristics under Load-Bearing Conditions
406 -
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Part 5 - General Discussion: The Effect of Micromotion on Bone Healing
415 - Part 6: Retrieval Analysis for Interpreting Interfacial Phenomena
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38. Bone-Biomaterial Interfaces of Retrieved Implants
419 -
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39. Ultrastructural Investigation and Analysis of the Interface of Retrieved Metal Implants
425 -
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40. Synovial Cells at the Interface with Retrieved Implants
438 -
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41. Phenotypic Characteristics of Inflammatory Cells Derived from Hip Revision Capsules
444 -
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42. Bone Bonding to Retrieved Hydroxyapatite- Coated Human Hip Prostheses
450 -
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Part 6 - General Discussion
457 -
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Part 7: The Industrial Perception
461 -
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Biographical Sketches of Invited Attendees at the Bone-Biomaterial Interface Workshop, Toronto, December 3 and 4, 1990
471 -
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Affiliations of Contributing Authors
481 -
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Index
487
Publishing information
Pages and Images/Illustrations in book
eBook published on:
November 30, 1991
eBook ISBN:
9781442671508
Pages and Images/Illustrations in book
Main content:
352
eBook ISBN:
9781442671508
Audience(s) for this book
College/higher education;Professional and scholarly;