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Synthesis of conjugated (E,E)-1,3-diene-containing troponoid-based compounds

  • Wen-Tao Gao EMAIL logo , Yan Yan and Yang Li
Published/Copyright: June 22, 2012
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Abstract

Through exploration of the electrophilic substitution reaction of 3-((2E,4E)-5-phenylpenta-2,4-dienoyl)-2-hydroxy-2,4,6-cycloheptatrien-1-one (3-((2E,4E)-5-phenylpenta-2,4-dienoyl)tropolone) with halogen and diazonium salts as well as the nucleophilic cyclisation reaction with hydroxylamine hydrochloride and substituted phenylhydrazine hydrochlorides by employing our reliable methods, we have synthesised a series of new (E,E)-1,3-diene-bearing troponoid-based compounds. All the newly synthesised molecules represent an issue of great interest, since the presence of conjugated 1,3-diene moiety can be developed further via other reactions.

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Published Online: 2012-6-22
Published in Print: 2012-7-1

© 2012 Institute of Chemistry, Slovak Academy of Sciences

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