Synthesis and antimicrobial activity of quinoline-based 2-pyrazolines
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Munawar Munawar
,
Muhammad Azad
Abstract
A series of 2-pyrazolines was prepared in a reaction of quinolinylchalcones with phenyl hydrazine under both conventional and microwave-induced heating. Structures of the synthesized compounds were characterized by spectroscopic data and CHN analyses. All prepared compounds were tested for antimicrobial activity against bacterial strains, viz. Staphylococcus aureus, Salmonella typhii, Escherichia coli, and Shigella dysentery. Almost all synthesized compounds have shown antimicrobial activity; however, compounds with a chloro group as a substituent have been found to be more effective.
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© 2008 Institute of Chemistry, Slovak Academy of Sciences
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Artikel in diesem Heft
- Evaluation of a spectroscopic tandem method using information theory
- Bioreduction of ionic mercury from wastewater in a fixed-bed bioreactor with activated carbon
- Simultaneous production of citric acid and erythritol from crude glycerol by Yarrowia lipolytica Wratislavia K1
- Entropy criterion of random states for granular material in a mixing process
- Extraction of copper ions using silica gel with chemically modified surface
- Synthesis and electrical properties of CuBr2 complexes with 1,10-phenanthroline monohydrate
- Complexes of transition metals bonded to silica via β-diketonate groups — synthesis, structure, and catalytic activity
- Preparation of α-methyl-γ-butyrolactone: Mechanism of its formation and utilization in 2-methyl-1-tetralone synthesis
- Preparation and antiplatelet activity of glycidic acid derivatives
- Synthesis and antimicrobial activity of quinoline-based 2-pyrazolines
- On the tautomerism of 1-phenyl-3-substituted-pyrazol-5-ones and their photoinduced products — experimental and theoretical UV spectral analysis
- Prediction of excess molar volumes of binary mixtures of organic compounds from refractive indices
- Efficient cyclodehydration of diethylene glycol in Brønsted acidic ionic liquids
- Spectrofluorimetric determination of uric acid based on its activation of catalytic oxidation of pyronine Y
- Packed column inlet as a direct injection capillary inlet
- In situ and ex situ characterization of a Fe-Cr-Ni alloy in mouthwashes and Hank’s solution
- Synthesis of 2-methyl-2-propoxypropyl isocyanide and its Cu(I) tetraflouroborate complex
- Study of CuI catalyzed coupling reactions of aryl bromides with imidazole and aliphatic amines under microwave dielectric heating
