Multicomponent facile synthesis of novel dihydroazolopyrimidinyl carbamides
-
E. Gladkov
,
S. Sirko
Abstract
Number of novel derivatives of dihydrotriazolo-and-tetrazolopyrimidines containing carboxamide group in position 6 were obtained by multicomponent Biginelli-type reaction. The structures of all synthesized compounds were proved by NMR and MS spectral methods. The method of three-component Biginelli-type reaction is well suited for the synthesis of new promising dihydroazolopyrimidines providing a scaffold for screening of biological activity.
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© 2007 Institute of Chemistry, Slovak Academy of Sciences
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- Spectrophotometric determination of microamounts of quercetin based on its complexation with copper(II)
- Oxygen evolution on Ti/Co3O4-coated electrodes in alkaline solution
- The zeta potential of kaolin suspensions measured by electrophoresis and electroacoustics
- Fluidization behavior of oil-contaminated sand
- Software sensors for monitoring of a solid waste composting process
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- Acidity, lipophilicity, solubility, absorption, and polar surface area of some ACE inhibitors
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