Voltammetric Behaviour of Pentoxifylline at Mercury Electrode
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Ender Biçer
Abstract
The voltammetric behaviour of pentoxifylline (1-(5′-oxohexyl)-3,7-dimethylxanthine, PTX) was studied in several supporting electrolytes (Britton–Robinson buffer of pH 2–12, 0.1 M NH3/NH4Cl buffer (pH 9.08), 0.1 M Na2B4O7 (pH 9.30), 0.1 M KCl (pH 6.22). At 0.1 M Britton–Robinson buffer (pH 7.46) PTX gives two peaks at −0.150 V and −1.524 V, respectively. At low pH values (pH < 5.50), the second peak was obscured by the hydrogen evolution while the first peak is well defined at 0.1 M KNO3 supporting electrolyte (pH 6.22). The potential of the second peak is practically pH-independent in the pH range of 6.50–11.00. The peaks (at −0.150 V and −1.524 V) are attributed to the reduction of Hg(I)-PTX complex and carbonyl group at 5′-oxohexyl moiety of the molecule, respectively. The relationship between peak current of carbonyl group and concentration of PTX is linear in 1.48 × 10−5 − 1.34 × 10−4 M concentration range in 0.1 M KCl (pH 6.22). It was observed that PTX has adsorption/desorption characteristics. A plausible mechanism is proposed for the electrode reaction of PTX on the mercury electrode.
© 2004 Oldenbourg Wissenschaftsverlag GmbH
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- Electrochemical Lithium Insertion/Extraction in Partially Reduced α-MoO3
- Voltammetric Behaviour of Pentoxifylline at Mercury Electrode
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Artikel in diesem Heft
- Homogeneous Ice Nucleation in Water and Aqueous Solutions
- Electrochemical Lithium Insertion/Extraction in Partially Reduced α-MoO3
- Voltammetric Behaviour of Pentoxifylline at Mercury Electrode
- Spectrophotometric Studies of Reactions of the Aquapentacyanoferrate(II) Ion with Ketones. Kinetics and Mechanism of the Substitution Reaction of the Aquapentacyanoferrate(II) Ion with 1-Benzoylethylpyridinium Chloride
- Effect of Electrolytes on the Aggregation of Sodium Dodecyl Sulphate: the Interactions of Different Counterions with Formed Micelles
- Reversible Gas Adsorption in Coated Wall Flow Tube Reactors. Model Simulations for Langmuir Kinetics
- Polyanionic Selenium Fragments and Vibrations in NaMSeN Clusters
- Book Review
