Charged particle induced reaction cross section data for production of the emerging medically important positron emitter 64Cu: A comprehensive evaluation
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M. Aslam
Abstract
The radionuclide 64Cu (T1/2=12.7 h) is an important non-standard positron emitter, suitable for combining PET imaging and targeted therapy. Its production in no-carrier-added form is done via charged particle induced reactions, and considerable amount of cross section data are available in the literature. We evaluated seven reactions, namely 64Ni(p, n) 64Cu, 64Ni(d, 2n) 64Cu, 68Zn(p, αn) 64Cu, 66Zn(p, 2n) 64Cu, 64Zn(d, 2p) 64Cu, 66Zn(p, α) 64Cu and natZn(d, x) 64Cu. Data analysis was generally limited up to about 25 MeV and the consistency check of experimental data was carried out using the nuclear model codes STAPRE, EMPIRE and TALYS. In a few cases experimental data were available up to 100 MeV; the consistency check in the high energy region was done only using the code TALYS. A statistical procedure (supported by nuclear model calculations) was then used to fit the data. The derived recommended sets of data, together with 95% confidence limits, are reported. The integral yields calculated from those data are also given. A critical comparison of the various production routes of 64Cu is presented. The 64Ni(p, n) 64Cu reaction, utilizing a highly enriched target, is the method of choice.
© by Oldenbourg Wissenschaftsverlag, München, Germany
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Articles in the same Issue
- Production and separation of no-carrier-added 93,94,95Tc from 9Be activated yttrium target
- Charged particle induced reaction cross section data for production of the emerging medically important positron emitter 64Cu: A comprehensive evaluation
- Determination of 126Sn half-life from ICP-MS and gamma spectrometry measurements
- Investigation of K to L shell/subshell vacancy transitions of Zn and Fe in FexZn1-x thin film alloys
- X-ray absorption spectroscopic study of trivalent and tetravalent actinides in solution at varying pH values
- Kinetic and thermodynamic studies on the adsorption of U(VI) ions on densely crosslinked poly(methacrylic acid) from aqueous solutions
- Extraction of americium(III) from nitric acid medium by CMPO-TBP extractants in ionic liquid diluent
- Uranium, plutonium and neptunium co-recovery with high nitric acid concentration in extraction section by simplified solvent extraction process
- Separation of 109Cd from silver targets by nanohematite
- An adapted purification procedure to improve the quality of 90Y for clinical use
- Novel polymer vectors of 64Cu
- Radiosynthesis of a novel potential adenosine A3 receptor ligand, 5-ethyl 2,4-diethyl-3-((2-[18F]fluoroethyl)sulfanylcarbonyl)-6-phenylpyridine-5-carboxylate ([18F]FE@SUPPY:2)
- Determination of solubility parameters of cobalt(II) and indium(III) oxinates by tracer technique
- Evaluation of trace elements in chewing tobacco and snuff using instrumental neutron activation analysis (INAA) and atomic absorption spectroscopy (AAS)
