A new diphenylheptanoid from the rhizomes of Curcuma zedoaria
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Truong Nhat Van Do
,
Hai Xuan Nguyen
,
Tho Huu Le
,
Phu Hoang Dang
,
Mai Thanh Nguyen
Abstract
A phytochemical investigation of the rhizomes of Curcuma zedoaria was carried out, leading to the isolation of a new diphenylheptanoid, zedoaroxane A (1), together with four known compounds (2–5). Their structures were elucidated based on NMR spectroscopic data. All isolated compounds possessed α-glucosidase inhibitory activity, with the IC50 values ranging from 35.2 to 89.0 µM, more potent than that of the positive control acarbose (IC50, 214.5 µM).
Acknowledgements
This research was supported by The Youth Incubator for Science and Technology Programe, managed by Youth Development Science and Technology Center – Ho Chi Minh Communist Youth Union and Department of Science and Technology of Ho Chi Minh City, the contract number is 30/2019/HĐ-KHCN-VƯ.
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Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
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Research funding: None declared.
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Conflict of interest statement: No potential conflict of interest was reported by the authors.
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Supplementary Material
Copies of spectroscopic data and HPLC chromatogram for 1 (Figures S1–S11).
The online version of this article offers supplementary material (https://doi.org/10.1515/znc-2021-0096).
© 2021 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
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Artikel in diesem Heft
- Frontmatter
- Research Articles
- Effect of Origanum dubium, Origanum vulgare subsp. hirtum, and Lavandula angustifolia essential oils on lipid profiles and liver biomarkers in athletes
- Role of Hypericum perforatum oil and pomegranate seed oil in wound healing: an in vitro study
- Establishment and metabonomics analysis of nonalcoholic fatty liver disease model in golden hamster
- Essential oils of Uvaria boniana – chemical composition, in vitro bioactivity, docking, and in silico ADMET profiling of selective major compounds
- A new diphenylheptanoid from the rhizomes of Curcuma zedoaria
- Review Article
- An update on the progress of microbial biotransformation of commercial monoterpenes
- Research Articles
- Synthesis, characterization, and computational study of copper bipyridine complex [Cu (C18H24N2) (NO3)2] to explore its functional properties
- Secondary metabolites from Detarium microcarpum Guill. and Perr. (Fabaceae)
