Regioselective synthesis of salicylates and acetophenones by formal [3+3]-cyclocondensations of 3-oxoorthoesters with 1,3-bis(trimethylsilyloxy)-1,3-butadienes
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Jörg-Peter Gütlein
Abstract
A variety of 4-methoxysalicylates and related polyketide-type phenols are regioselectively prepared by formal [3+3] cyclocondensations of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with 3-oxo-orthoesters. Cycloalkyl-substituted salicylates were prepared for the first time.
Acknowledgements
Financial support by the State of Mecklenburg-Vorpommern is gratefully acknowledged.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: State of Mecklenburg-Vorpommern.
Conflict of interest statement: The authors declare no conflicts of interest regarding this article.
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Articles in the same Issue
- Frontmatter
- In this issue
- Research Articles
- Regioselective synthesis of salicylates and acetophenones by formal [3+3]-cyclocondensations of 3-oxoorthoesters with 1,3-bis(trimethylsilyloxy)-1,3-butadienes
- Crystal structure, Hirshfeld surface analysis and Pixel calculations of the monohydrate of (E)-3-(2-hydroxy-5-methoxyphenyl)-1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one: occurrence of π interactions
- Two-dimensional lanthanide(III) coordination polymers: solvothermal synthesis, crystal structure, and stability
- Single-crystal X-ray structure determinations of vardenafil, vardenafil dihydrate, vardenafil monohydrochloride trihydrate and vardenafil dihydrochloride hexahydrate
- Assembly, photocatalytic and fluorescence properties of three new coordination complexes of zinc(II) and nickel(II) with two kinds of flexible bis(pyridyl)-bis(amide) ligands
- Two luminescent d10 metal coordination polymers based on 3-nitro-5-(pyridin-3-yl)benzoic acid
- High-pressure synthesis of REB5O8(OH)2 (RE = Ho, Er, Tm)
- A novel three-dimensional cadmium sulfate-based inorganic-organic hybrid polymer with green photoluminescence
Articles in the same Issue
- Frontmatter
- In this issue
- Research Articles
- Regioselective synthesis of salicylates and acetophenones by formal [3+3]-cyclocondensations of 3-oxoorthoesters with 1,3-bis(trimethylsilyloxy)-1,3-butadienes
- Crystal structure, Hirshfeld surface analysis and Pixel calculations of the monohydrate of (E)-3-(2-hydroxy-5-methoxyphenyl)-1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one: occurrence of π interactions
- Two-dimensional lanthanide(III) coordination polymers: solvothermal synthesis, crystal structure, and stability
- Single-crystal X-ray structure determinations of vardenafil, vardenafil dihydrate, vardenafil monohydrochloride trihydrate and vardenafil dihydrochloride hexahydrate
- Assembly, photocatalytic and fluorescence properties of three new coordination complexes of zinc(II) and nickel(II) with two kinds of flexible bis(pyridyl)-bis(amide) ligands
- Two luminescent d10 metal coordination polymers based on 3-nitro-5-(pyridin-3-yl)benzoic acid
- High-pressure synthesis of REB5O8(OH)2 (RE = Ho, Er, Tm)
- A novel three-dimensional cadmium sulfate-based inorganic-organic hybrid polymer with green photoluminescence
