Triethanolamine-modified poloxamer temperature-sensitive hair care gel for intelligent controlled release of sodium thioglycolat
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Wenrui Zheng
Wenrui Zheng is a postgraduate student at the School of Chemical and Material Engineering, Jiangnan University. Her research interests focus on emulsion and hair-dying.
Yue Lei is a postgraduate student at the School of Chemical and Material Engineering, Jiangnan University. Her research interests focus on emulsion and hair treatment.
Yuheng Li is a postgraduate student at the School of Chemical and Material Engineering, Jiangnan University. His research interests focus on emulsion and hair-dying.
Haiyan Gao is a associate professor at the School of Chemical and Material Engineering, Jiangnan University. She received her Ph.D. in science from the Institute of Coal Chemistry, Chinese Academy of Sciences in 2003. Her research interests include physical chemistry, synthesis and application of chemicals.
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Liangliang Lin
Liangliang Lin is a professor at the School of Chemical and Material Engineering, Jiangnan University. He received his Ph.D. from Eindhoven University of Technology in 2018. He is mainly involved in the research of chemical process intensification technologies (plasma and microreactor technologies) and the development and application of daily chemicals and surfactants, and has a solid research foundation and experience in this field.
Abstract
A triethanolamine-modified poloxamer temperature-sensitive hair care gel was formulated in order to reduce the adverse health effects associated with sodium thioglycolate (TGA(Na)), the active component in hair treatment agents, while maintaining excellent efficacy. It was found that TEA-3 gelled at 32 °C with a triethanolamine concentration of 3 %. This formulation exhibited a reversible phase transition, transitioning to a solid state upon contact with the scalp (>32 °C) and reverting to a liquid state when in contact with hair (<32 °C). The release behavior of TGA(Na) from the gel was assessed by both in vitro release studies and transdermal experiments. In addition, it was observed that the triethanolamine-modified poloxamer gel exhibited improved hair care efficiency compared to conventional hair care agents. These results suggest that the triethanolamine-modified poloxamer gel is a promising alternative to conventional hair care products, offering improved efficacy while minimizing potential adverse health effects.
Funding source: Central University Basic Research Fund of China
Award Identifier / Grant number: JUSRP622038
Funding source: Postdoctoral Science Foundation of China
Award Identifier / Grant number: 2023M741472
About the authors
Wenrui Zheng is a postgraduate student at the School of Chemical and Material Engineering, Jiangnan University. Her research interests focus on emulsion and hair-dying.
Yue Lei is a postgraduate student at the School of Chemical and Material Engineering, Jiangnan University. Her research interests focus on emulsion and hair treatment.
Yuheng Li is a postgraduate student at the School of Chemical and Material Engineering, Jiangnan University. His research interests focus on emulsion and hair-dying.
Haiyan Gao is a associate professor at the School of Chemical and Material Engineering, Jiangnan University. She received her Ph.D. in science from the Institute of Coal Chemistry, Chinese Academy of Sciences in 2003. Her research interests include physical chemistry, synthesis and application of chemicals.
Liangliang Lin is a professor at the School of Chemical and Material Engineering, Jiangnan University. He received his Ph.D. from Eindhoven University of Technology in 2018. He is mainly involved in the research of chemical process intensification technologies (plasma and microreactor technologies) and the development and application of daily chemicals and surfactants, and has a solid research foundation and experience in this field.
Acknowledgments
Thank you to my mentor Haiyan Gao for her careful guidance. I would like to express my gratitude to Senior Sister Yue Lei, Senior Brother Yuheng Li, and fellow laboratory mates for their assistance during the experimental process. Special thanks to the instructors of various testing instruments for their patient guidance during my experiments.
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Research ethics: Not applicable.
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Informed consent: Not applicable.
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Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission. Wenrui Zheng: experimental design, experiment execution, data collection and analysis, figure creation, manuscript writing; Yue Lei: experimental design; Yuheng Li: resources; Haiyan Gao: experimental design, review and editing; Liangliang Lin: technical support, review and editing; Hujun Xu: technical support, review and editing.
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Use of Large Language Models, AI and Machine Learning Tools: None declared.
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Conflict of interest: The authors state no conflict of interest.
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Research funding: We would like to acknowledge the financial support from the Postdoctoral Science Foundation of China (2023M741472) and the Central University Basic Research Fund of China (JUSRP622038).
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Data availability: Not applicable.
References
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Articles in the same Issue
- Frontmatter
- Review Article
- Toxicity and environmental aspects of surfactants
- Physical Chemistry
- Ionic surfactants critical micelle concentration prediction in water/organic solvent mixtures by artificial neural network
- Study on rheology of novel UV/visible light sensitive trimeric cationic surfactant/trans-4-phenylazo benzoic acid micelle system
- Improvement in the thermal, mechanical and rheological properties of polyamide-11 (PA11) nanobiocomposite films as a result of the influence of the composition and type of nanofiller
- Body Care Products
- Triethanolamine-modified poloxamer temperature-sensitive hair care gel for intelligent controlled release of sodium thioglycolat
- Drug Delivery Systems
- Formulation of Felodipine lipid nanoparticle-loaded oral fast-dissolving films
- Applications
- The effect of addition of sodium hexadecyl sulfate on the performance properties of lauramidopropyl betaine
- The role of presence of wormlike micelles of ionic surfactants on the sterilization efficiency of sodium hypochlorite
- Synthesis
- Synthesis and performance study of a new surfactant with corrosion inhibition function
- Synthesis and surfactant properties of sulfonate Gemini surfactants
- Short Communication
- Preparation and stability of lipid nanoparticles excluding 1,2-distearoyl-sn-glycero-3-phosphocholine
Articles in the same Issue
- Frontmatter
- Review Article
- Toxicity and environmental aspects of surfactants
- Physical Chemistry
- Ionic surfactants critical micelle concentration prediction in water/organic solvent mixtures by artificial neural network
- Study on rheology of novel UV/visible light sensitive trimeric cationic surfactant/trans-4-phenylazo benzoic acid micelle system
- Improvement in the thermal, mechanical and rheological properties of polyamide-11 (PA11) nanobiocomposite films as a result of the influence of the composition and type of nanofiller
- Body Care Products
- Triethanolamine-modified poloxamer temperature-sensitive hair care gel for intelligent controlled release of sodium thioglycolat
- Drug Delivery Systems
- Formulation of Felodipine lipid nanoparticle-loaded oral fast-dissolving films
- Applications
- The effect of addition of sodium hexadecyl sulfate on the performance properties of lauramidopropyl betaine
- The role of presence of wormlike micelles of ionic surfactants on the sterilization efficiency of sodium hypochlorite
- Synthesis
- Synthesis and performance study of a new surfactant with corrosion inhibition function
- Synthesis and surfactant properties of sulfonate Gemini surfactants
- Short Communication
- Preparation and stability of lipid nanoparticles excluding 1,2-distearoyl-sn-glycero-3-phosphocholine
