Lamellar liquid crystals formed from sucrose ester and Brij97 solutions for curcumin delivery
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Fumin Guo
Mr. Fumin Guo, Mr. Xuepeng Li, and Mr. Jun Fan, all Masters, graduated from College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University.
Mr. Fumin Guo, Mr. Xuepeng Li, and Mr. Jun Fan, all Masters, graduated from College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University.
Mr. Fumin Guo, Mr. Xuepeng Li, and Mr. Jun Fan, all Masters, graduated from College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University.
Mr. Xuebin Ma, Ph.D., received his Ph.D. from Nanjing University of Science and Technology in 2019. His main research interests include drug carriers, wound dressings, tissue engineering, etc.
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Zhongni Wang
Mrs. Zhongni Wang, Professor, teaches at College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, and her main research interests are the preparation of surfactant-ordered aggregates and their applications in biomedicine.
Abstract
In this paper, the lamellar liquid crystals formed in S1570-Brij97/isopropyl myristate/PEG400 aqueous system were prepared at 37 °C. The effects of PEG400 and curcumin on the S1570-Brij97 lyotropic liquid crystal systems were studied by phase diagram, polarized optical microscopy, small angle X-ray scattering, and rheology. The prepared lamellar liquid crystals show stable structures at 37 °C. The encapsulation of curcumin improves the structural stability of the lamellar liquid crystals, which can be confirmed by their higher η γ=0.013 and σ y values, suggesting that the S1570-Brij97 lamellar liquid crystals are good carriers for curcumin. In addition, the prepared lamellar liquid crystals can effectively protect curcumin from decomposition, and curcumin can be released slowly in the liquid crystals. Therefore, based on the structural stability, protective effect on curcumin, and slow-release behavior, the constructed S1570-Brij97 lamellar liquid crystals have good potential for drug delivery.
Funding source: National Natural Science Foundation of China
Award Identifier / Grant number: 31271933
About the authors
Mr. Fumin Guo, Mr. Xuepeng Li, and Mr. Jun Fan, all Masters, graduated from College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University.
Mr. Fumin Guo, Mr. Xuepeng Li, and Mr. Jun Fan, all Masters, graduated from College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University.
Mr. Fumin Guo, Mr. Xuepeng Li, and Mr. Jun Fan, all Masters, graduated from College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University.
Mr. Xuebin Ma, Ph.D., received his Ph.D. from Nanjing University of Science and Technology in 2019. His main research interests include drug carriers, wound dressings, tissue engineering, etc.
Mrs. Zhongni Wang, Professor, teaches at College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, and her main research interests are the preparation of surfactant-ordered aggregates and their applications in biomedicine.
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Research ethics: The local Institutional Review Board deemed the study exempt from review.
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Author contributions: Fumin Guo carried out all experiments, and wrote the first draft of the manuscript. Fumin Guo, Xuepeng Li, and Jun Fan analyzed all data. Xuebin Ma: Writing-review & editing. Zhongni Wang: Conceptualization, Supervision. The authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Competing interests: The authors state no conflict of interest.
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Research funding: This work was supported by the National Natural Science Foundation of China (31271933).
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Data availability: The raw data can be obtained on request from the corresponding author.
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Supplementary Material
This article contains supplementary material (https://doi.org/10.1515/tsd-2023-2569).
© 2024 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
- Frontmatter
- Biosurfactants
- Study on the properties of branched-chain alkyl glycoside nonionic surfactant and anionic surfactant in a mixed system
- Aggregation behavior and thermodynamic parameters of biosurfactants (NaC/NaDC) in aqueous medium of Emtricitabine and Lamivudine (anti-HIV drugs)
- Drug Release Systems
- Lamellar liquid crystals formed from sucrose ester and Brij97 solutions for curcumin delivery
- Surface Active Ionic Liquids
- The influence of herbicidal anions on chemical shifts in NMR, phytotoxicity and surface properties of pyrrolidinium surface-active ionic liquids
- Applications
- Study on an all-in-one foaming agent with corrosion inhibition for air foam flooding
- Study on the scale inhibition performance of organic chelating agent aided by surfactants on CaCO3 at high salinity condition
- Study on the influence of emulsification ability of oil displacement system on its chemical flooding recovery
- Effect of contaminated water (handwashing detergent) on seed germination traits in wheat, mung bean, and chickpea
- Synthesis
- Synthesis and application feasibility study of cetyltrimethylammonium p-toluenesulfonate
Artikel in diesem Heft
- Frontmatter
- Biosurfactants
- Study on the properties of branched-chain alkyl glycoside nonionic surfactant and anionic surfactant in a mixed system
- Aggregation behavior and thermodynamic parameters of biosurfactants (NaC/NaDC) in aqueous medium of Emtricitabine and Lamivudine (anti-HIV drugs)
- Drug Release Systems
- Lamellar liquid crystals formed from sucrose ester and Brij97 solutions for curcumin delivery
- Surface Active Ionic Liquids
- The influence of herbicidal anions on chemical shifts in NMR, phytotoxicity and surface properties of pyrrolidinium surface-active ionic liquids
- Applications
- Study on an all-in-one foaming agent with corrosion inhibition for air foam flooding
- Study on the scale inhibition performance of organic chelating agent aided by surfactants on CaCO3 at high salinity condition
- Study on the influence of emulsification ability of oil displacement system on its chemical flooding recovery
- Effect of contaminated water (handwashing detergent) on seed germination traits in wheat, mung bean, and chickpea
- Synthesis
- Synthesis and application feasibility study of cetyltrimethylammonium p-toluenesulfonate
