The role of peripheral nerve ECM components in the tissue engineering nerve construction

References

Ahmed, M.R., and Jayakumar, R. (2003). Peripheral nerve regeneration in RGD peptide incorporated collagen tubes. Brain Res. 993, 208–216.10.1016/j.brainres.2003.08.057Search in Google Scholar

Ahmed, Z., Underwood, S., and Brown, R.A. (2003). Nerve guide material made from fibronectin: assessment of in vitro properties. Tissue Eng. 9, 219–231.10.1089/107632703764664693Search in Google Scholar

Allodi, I., Udina, E., and Navarro, X. (2012). Specificity of peripheral nerve regeneration: interactions at the axon level. Prog. Neurobiol. 98, 16–37.10.1016/j.pneurobio.2012.05.005Search in Google Scholar

Ansselin, A.D., and Pollard, J.D. (1990). Immunopathological factors in peripheral nerve allograft rejection: quantification of lymphocyte invasion and major histocompatibility complex expression. J. Neuro. Sci. 96, 75–88.10.1016/0022-510X(90)90058-USearch in Google Scholar

Aquino, D.A., Margolis, R.U., and Margolis, R.K. (1984). Immunocytochemical localization of a chondroitin sulfate proteoglycan in nervous tissue. adult brain, retina, and peripheral nerve. J. Cell Biol. 99, 1117–1129.10.1083/jcb.99.3.1117Search in Google Scholar PubMed PubMed Central

Bozkurt, A., Brook, G.A., Moellers, S., Lassner, F., Sellhaus, B., Weis, J., Woeltje, M., Tank, J., Beckmann, C., Fuchs, P., et al. (2007). In vitro assessment of axonal growth using dorsal root ganglia explants in a novel three-dimensional collagen matrix. Tissue Eng. 13, 2971–2979.10.1089/ten.2007.0116Search in Google Scholar PubMed

Bozkurt, A., Lassner, F., O’Dey, D., Deumens, R., Bocker, A., Schwendt, T., Janzen, C., Suschek, C.V., Tolba, R., Kobayashi, E., et al. (2012). The role of microstructured and interconnected pore channels in a collagen-based nerve guide on axonal regeneration in peripheral nerves. Biomaterials 33, 1363–1375.10.1016/j.biomaterials.2011.10.069Search in Google Scholar PubMed

Bruns, S., Stark, Y., Roker, S., Wieland, M., Drager, G., Kirschning, A., Stahl, F., Kasper, C., and Scheper, T. (2007). Collagen biomaterial doped with colominic acid for cell culture applications with regard to peripheral nerve repair. J. Biotechnol. 131, 335–345.10.1016/j.jbiotec.2007.06.024Search in Google Scholar PubMed

Cao, J., Sun, C., Zhao, H., Xiao, Z., Chen, B., Gao, J., Zheng, T., Wu, W., Wu, S., Wang, J., et al. (2011). The use of laminin modified linear ordered collagen scaffolds loaded with laminin-binding ciliary neurotrophic factor for sciatic nerve regeneration in rats. Biomaterials 32, 3939–3948.10.1016/j.biomaterials.2011.02.020Search in Google Scholar PubMed

Chen, Z.L., and Strickland, S. (2003). Laminin gamma1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve. J. Cell Biol. 163, 889–899.10.1083/jcb.200307068Search in Google Scholar PubMed PubMed Central

Chen, Y.-S., Hsieh, C.-L., Tsai, C.-C., Chen, T.-H., Cheng, W.-C., Hu, C.-L., and Yao, C.-H. (2000). Peripheral nerve regeneration using silicone rubber chambers filled with collagen, laminin and fibronectin. Biomaterials 21, 1541–1547.10.1016/S0142-9612(00)00028-4Search in Google Scholar

Chernousov, M.A., Yu, W.-M., Chen, Z.-L., Carey D.J., and Strickland S. (2008). Regulation of Schwann cell function by the extracellular matrix. Glia 56, 1498–1507.10.1002/glia.20740Search in Google Scholar

Colognato, H., and Yurchenco, P.D. (2000). Form and function: the laminin family of heterotrimers. Dev. Dyn. 218, 213–234.10.1002/(SICI)1097-0177(200006)218:2<213::AID-DVDY1>3.0.CO;2-RSearch in Google Scholar

Cui, T., Yan, Y., Zhang, R., Liu, L., Xu, W., and Wang, X. (2009). Rapid prototyping of a double-layer polyurethane-collagen conduit for peripheral nerve regeneration. Tissue Eng. 15, 1–9.10.1089/ten.tec.2008.0354Search in Google Scholar

Curinga, G.M., Snow, D.M., Mashburn, C., Kohler, K., Thobaben, R., Caggiano, A.O., and Smith, G.M. (2007). Mammalian-produced chondroitinase AC mitigates axon inhibition by chondroitin sulfate proteoglycans. J. Neurochem. 102, 275–288.10.1111/j.1471-4159.2007.04530.xSearch in Google Scholar

Deumens, R., Bozkurt, A., Meek, M.F., Marcus, M.A., Joosten, E.A., Weis, J., and Brook, G.A. (2010). Repairing injured peripheral nerves: bridging the gap. Prog. Neurobiol. 92, 245–276.10.1016/j.pneurobio.2010.10.002Search in Google Scholar

Dewitt, D.D., Kaszuba, S.N., Thompson, D.M., and Stegemann, J.P. (2008). Collagen 1 Matrigel scaffolds for enhanced Schwann cell survival and control of three-dimensional cell morphology. Tissue Eng. 15, 2785–2793.10.1089/ten.tea.2008.0406Search in Google Scholar

Deyst, K.A., Bowe, M.A., Leszyk, J.D., and Fallon, J.R. (1995). The a-dystroglycan-b-dystroglycan complex. Membrane organization and relationship to an agrin receptor. J. Biol. Chem. 270, 25956–25959.10.1074/jbc.270.43.25956Search in Google Scholar

Ding, T., Luo, Z.J., Zheng, Y., Hu, X.Y., and Ye, Z.X. (2010). Rapid repair and regeneration of damaged rabbit sciatic nerves by tissue-engineered scaffold made from nano-silver and collagen type I. Injury 41, 522–527.10.1016/j.injury.2009.04.003Search in Google Scholar

Ding, T., Lu, W.W., Zheng, Y., Li, Zy., Pan, H.B., and Luo, Z. (2011). Rapid repair of rat sciatic nerve injury using a nanosilver-embedded collagen scaffold coated with laminin and fibronectin. Future Med. 6, 437–447.10.2217/rme.11.39Search in Google Scholar

Ernst, S., Langer, R., Cooney, C.L., and Sasisekharan, R. (1995). Enzymatic degradation of glycosaminoglycans. Crit. Rev. Biochem. Mol. Biol. 30, 387–444.10.3109/10409239509083490Search in Google Scholar PubMed

Ervasti, J.M., and Campbell, K.P. (1993). A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and agrin. J. Cell Biol. 122, 809–823.10.1083/jcb.122.4.809Search in Google Scholar PubMed PubMed Central

Evercooren, A.B.-V., Kleinman, H.K., Seppa, H.E.J., Rentier, B., and Dubois-Dalcq, M. (1982). Fibronectin promotes rat Schwann cell growth and motility. J. Cell Biol. 93, 211–216.10.1083/jcb.93.1.211Search in Google Scholar PubMed PubMed Central

Fu, S.Y., and Gordon, T. (1997). The cellular and molecular basis of peripheral nerve regeneration. Mol. Neurobiol. 14, 67–116.10.1007/BF02740621Search in Google Scholar PubMed

Gardiner, N.J., Moffatt, S., Fernyhough, P., Humphries, M.J., Streuli, C.H., and Tomlinson, D.R. (2007). Preconditioning injury-induced neurite outgrowth of adult rat sensory neurons on fibronectin is mediated by mobilisation of axonal alpha5 integrin. Mol. Cell. Neurosci. 35, 249–260.10.1016/j.mcn.2007.02.020Search in Google Scholar PubMed

Goto, E., Mukozawa, M., Mori, H., and Hara, M. (2010). A rolled sheet of collagen gel with cultured Schwann cells: model of nerve conduit to enhance neurite growth. J. Biosci. Bioeng. 109, 512–518.10.1016/j.jbiosc.2009.11.002Search in Google Scholar PubMed

Gu, K., Linhardt, R.J., Laliberté, M., Gu, K., and Zimmermann, J. (1995). Purification, characterization and specificity of chondroitin lyases and glycuronidase from Flavobacterium heparinum. Biochem. J. 312, 569–577.10.1042/bj3120569Search in Google Scholar PubMed PubMed Central

Han, H., Ao, Q., Chen, G., Wang, S., and Zuo, H. (2009). A novel basic fibroblast growth factor delivery system fabricated with heparin-incorporated fibrin–fibronectin matrices for repairing rat sciatic nerve disruptions. Biotechnol. Lett. 32, 585–591.10.1007/s10529-009-0186-zSearch in Google Scholar PubMed

Hu, J., Zhu, Q.-T., Liu, X.-L., Xu, Y.-B., and Zhu, J.-K. (2007). Repair of extended peripheral nerve lesions in rhesus monkeys using acellular allogenic nerve grafts implanted with autologous mesenchymal stem cells. Exp. Neurol. 204, 658–666.10.1016/j.expneurol.2006.11.018Search in Google Scholar PubMed

Humphries, M.J., Akiyama, S.K., Komoriya, A., Olden, K., and Yamada, K.M. (1988). Neurite extension of chicken peripheral nervous system neurons on fibronectin: relative importance of specific adhesion sites in the central cell-binding domain and the alternatively spliced type 3 connecting segment. J. Cell Biol. 106, 1289–1297.10.1083/jcb.106.4.1289Search in Google Scholar PubMed PubMed Central

Hynes, R.O. (2002). Integrins: bidirectional, allosteric signaling machines. Cell 110, 673–687.10.1016/S0092-8674(02)00971-6Search in Google Scholar

Ibraghimov-Beskrovnaya, O., Ervasti, J.M., Leveille, C.J., Slaughter, C.A., Sernett, S.W., and Campbell, K.P. (1992). Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix. Nature 355, 696–702.10.1038/355696a0Search in Google Scholar PubMed

Ide, C., Tohyama, K., Tajima, K., Endoh, K., Sano, K., Tamura, M., Mizoguchi, A., Kitada, M., Morihara, T., and Shirasu, M. (1998). Long acellular nerve transplants for allogeneic grafting and the effects of basic fibroblast growth factor on the growth of regenerating axons in dogs: a preliminary report. Exp. Neurol. 154, 99–112.10.1006/exnr.1998.6921Search in Google Scholar PubMed

Itoh, S., Takakuda, K., Samejima, H., Ohta, T., Shinomiya, K., and Ichinose, S. (1999). Synthetic collagen fibers coated with a synthetic peptide containing the YIGSR sequence of laminin to promote peripheral nerve regeneration in vivo. Mater. Med 10, 129–134.10.1023/A:1008977221827Search in Google Scholar

Jesuraj, N.J., Santosa, K.B., Newton, P., Liu, Z., Hunter, D.A., Mackinnon, S.E., Sakiyama-Elbert, S.E., and Johnson, P.J. (2011). A systematic evaluation of Schwann cell injection into acellular cold-preserved nerve grafts. J. Neurosci. Methods 197, 209–215.10.1016/j.jneumeth.2011.02.015Search in Google Scholar PubMed PubMed Central

Keilhoff, G., Goihl, A., Stang, F., Wolf, G., and Fansa, H. (2006). Peripheral nerve tissue engineering: autologous Schwann cells vs. transdifferentiated mesenchymal stem cells. Tissue Eng. 12, 1451–1465.10.1089/ten.2006.12.1451Search in Google Scholar PubMed

Kemp, S.W., Walsh, S.K., and Midha, R. (2008). Growth factor and stem cell enhanced conduits in peripheral nerve regeneration and repair. Neurol. Res. 30, 1030–1038.10.1179/174313208X362505Search in Google Scholar PubMed

Kemp, S.W., Syed, S., Walsh, W., Zochodne, D.W., and Midha, R. (2009). Collagen nerve conduits promote enhanced axonal regeneration, Schwann cell association, and neovascularization compared to silicone conduits. Tissue Eng. 15, 1975–1988.10.1089/ten.tea.2008.0338Search in Google Scholar PubMed

Krekoski, C.A., Neubauer, D., Zuo, J., and Muir, D. (2001). Axonal regeneration into acellular nerve grafts is enhanced by degradation of chondroitin sulfate proteoglycan. J. Neurosci. 21, 6206–6213.10.1523/JNEUROSCI.21-16-06206.2001Search in Google Scholar

Krolo, M., Viloviae, K., Sapunar, D., and Vrdoljak, E. (1998). Fibronectin expression in the developing human spinal cord, nerves, and ganglia. Croat. Med. J. 39, 386–391.Search in Google Scholar

Lander, A.D., Fujll, D.K., and Reichardt, L.F. (1985). Purification of a factor that promotes neurite outgrowth: isolation of laminin and associated molecules. J. Cell Biol. 101, 898–913.10.1083/jcb.101.3.898Search in Google Scholar PubMed PubMed Central

Lefcort, F., Venstrom, K., Mcdonald, J.A., and Reichardt, L.F. (1992). Regulation of expression of fibronectin and its receptor, a5b1, during development and regeneration of peripheral nerve. Development 116, 767–782.10.1242/dev.116.3.767Search in Google Scholar

Li, Z., Peng, J., Wang, G., Yang, Q., Yu, H., Guo, Q., Wang, A., Zhao, B., and Lu, S. (2008). Effects of local release of hepatocyte growth factor on peripheral nerve regeneration in acellular nerve grafts. Exp. Neurol. 214, 47–54.10.1016/j.expneurol.2008.07.007Search in Google Scholar

Lindholm, D., Heumann, R., Meyer, M., and Thoenen, H. (1987). Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve. Nature 330, 658–659.10.1038/330658a0Search in Google Scholar

Longo, F.M., Hayman, E.G., Davis, G.E., Ruoslahti, E., Engvall, E., Manthorpe, M., and Varon, S. (1984). Neurite-promoting factors and extracellular matrix components accumulating in vivo within nerve regeneration chambers. Brain Res. 309, 105–117.10.1016/0006-8993(84)91014-XSearch in Google Scholar

Madduri, S., Feldman, K., Tervoort, T., Papaloizos, M., and Gander, B. (2010). Collagen nerve conduits releasing the neurotrophic factors GDNF and NGF. J. Control Release 143, 168–174.10.1016/j.jconrel.2009.12.017Search in Google Scholar PubMed

Martini, R.M. (1994). Expression and functional roles of neural cell surface molecules and extracellular matrix components during development and regeneration of peripheral nerves. J. Neurocytol. 23, 1–28.10.1007/BF01189813Search in Google Scholar PubMed

Masaki, T., Matsumura, K., Saito, F., Yamada, H., Higuchi, S., Kamakura, K., Yorifuji, H., and Shimizu, T. (2003). Association of dystroglycan and laminin-2 coexpression with myelinogenesis in peripheral nerves. Med. Electron Microsc. 36, 221–239.10.1007/s00795-003-0231-2Search in Google Scholar PubMed

Masand, S.N., Chen, J., Perron, I.J., Hammerling, B.C., Loers, G., Schachner, M., and Shreiber, D.I. (2012a) The effect of glycomimetic functionalized collagen on peripheral nerve repair. Biomaterials 33, 8353–8362.10.1016/j.biomaterials.2012.08.018Search in Google Scholar PubMed PubMed Central

Masand, S.N., Perron, I.J., Schachner, M., and Shreiber, D.I. (2012b). Neural cell type-specific responses to glycomimetic functionalized collagen. Biomaterials 33, 790–797.10.1016/j.biomaterials.2011.10.013Search in Google Scholar PubMed PubMed Central

Maturana, L.G., Zanon, R.G., Pierucci, A., Vidal, B.C., and Oliveira, A.L.R. (2011). Supraorganized collagen enhances Schwann cell reactivity and organization in vitro. Braz. J. Med. Biol. Res. 44, 682–687.10.1590/S0100-879X2011007500074Search in Google Scholar

Mosahebi, A., Wiberg, M., and Terenghi, G. (2003). Addition of fibronectin to alginate matrix improves peripheral nerve regeneration in tissue-engineered conduits. Tissue Eng. 9, 209–218.10.1089/107632703764664684Search in Google Scholar

Nakamura, T., Inada, Y., Fukuda, S., Yoshitani, M., Nakada, A., Itoi, S., Kanemaru, S., Endo, K., and Shimizu, Y. (2004). Experimental study on the regeneration of peripheral nerve gaps through a polyglycolic acid-collagen (PGA-collagen) tube. Brain Res. 1027, 18–29.10.1016/j.brainres.2004.08.040Search in Google Scholar

Palm, S.L., and Furcht, L.T. (1983). Production of laminin and fibronectin by schwannoma cells: cell-protein interaction in vitro and protein localization in peripheral nerve in vitro. J. Cell Biol. 96, 1218–1226.10.1083/jcb.96.5.1218Search in Google Scholar

Patel, M., VandeVord, P.J., Matthew, H.W., DeSilva, S., Wu, B., and Wooley, P.H. (2008). Functional gait evaluation of collagen chitosan nerve guides for sciatic nerve repair. Tissue Eng. 14, 365–370.10.1089/ten.tec.2008.0166Search in Google Scholar

Pinkstaff, J.K., Detterich, J., Lynch, G., and Gall, C. (1999). Integrin subunit gene expression is regionally differentiated in adult brain. J. Neurosci. 19, 1541–1556.10.1523/JNEUROSCI.19-05-01541.1999Search in Google Scholar

Plantman, S., Patarroyo, M., Fried, K., Domogatskaya, A., Tryggvason, K., Hammarberg, H., and Cullheim, S. (2008). Integrin-laminin interactions controlling neurite outgrowth from adult DRG neurons in vitro. Mol. Cell. Neurosci. 39, 50–62.10.1016/j.mcn.2008.05.015Search in Google Scholar

Reist, N.E., Werle, M.J., and McMahan, U.J. (1992). Agrin released by motor neurons induces the aggregation of acetylcholine receptors at neuromuscular junctions. Neuron 8, 865–868.10.1016/0896-6273(92)90200-WSearch in Google Scholar

Ren, Z., Wang, Y., Peng, J., Zhao, Q., and Lu, S. (2012). Role of stem cells in the regeneration and repair of peripheral nerves. Rev. Neurosci. 23, 135–143.10.1515/revneuro-2011-0069Search in Google Scholar PubMed

Smyth, N., Vatansever, H.S., Murray, P., Meyer, M., Frie, C., Paulsson, M., and Edgar, D. (1999). Absence of basement membranes after targeting the LAMC1 gene results in embryonic lethality due to failure of endoderm differentiation. J. Cell. Biol. 144, 151–160.10.1083/jcb.144.1.151Search in Google Scholar PubMed PubMed Central

Stang, F., Fansa, H., Wolf, G., and Keilhoff, G. (2005a). Collagen nerve conduits – Assessment of biocompatibility and axonal regeneration. Biomed. Mater. Eng. 15, 3–12.Search in Google Scholar

Stang, F., Fansa, H., Wolf, G., Reppin, M., and Keilhoff, G. (2005b). Structural parameters of collagen nerve grafts influence peripheral nerve regeneration. Biomaterials 26, 3083–3091.10.1016/j.biomaterials.2004.07.060Search in Google Scholar PubMed

Suganuma, S., Tada, K., Hayashi, K., Takeuchi, A., Sugimoto, N., Ikeda, K., and Tsuchiya, H. (2013). Uncultured adipose-derived regenerative cells promote peripheral nerve regeneration. J. Orthop. Sci. 18, 145–151.10.1007/s00776-012-0306-9Search in Google Scholar PubMed

Sun, W., Sun, C., Lin, H., Zhao, H., Wang, J., Ma, H., Chen, B., Xiao, Z., and Dai, J. (2009a). The effect of collagen-binding NGF-beta on the promotion of sciatic nerve regeneration in a rat sciatic nerve crush injury model. Biomaterials 30, 4649–4656.10.1016/j.biomaterials.2009.05.037Search in Google Scholar PubMed

Sun, W., Sun, C., Zhao, H., Lin, H., Han, Q., Wang, J., Ma, H., Chen, B., Xiao, Z., and Dai, J. (2009b). Improvement of sciatic nerve regeneration using laminin-binding human NGF-B. PLOS ONE 4, 1–10.10.1371/journal.pone.0006180Search in Google Scholar PubMed PubMed Central

Sun, X.H., Che, Y.Q., Tong, X.J., Zhang, L.X., Feng, Y., Xu, A.H., Tong, L., Jia, H., and Zhang, X. (2009c). Improving nerve regeneration of acellular nerve allografts seeded with SCs bridging the sciatic nerve defects of rat. Cell. Mol. Neurobiol. 29, 347–353.10.1007/s10571-008-9326-6Search in Google Scholar PubMed

Suri, S., and Schmidt, C.E. (2010). Cell-laden hydrogel constructs of hyaluronic acid, collagen, and laminin for neural tissue engineering. Tissue Eng. 16, 1703–1716.10.1089/ten.tea.2009.0381Search in Google Scholar PubMed

Tkalec, A.L., Fink, D., Blain, F., Zhang-Sun, G., Laliberte, M., Bennett, D.C., Gu, K., Zimmermann, J.J., and Su. H. (2000). Isolation and expression in Escherichia coli of cslA and cslB, gene coding for the chondroitin sulfate-degrading enzymes chondroitinase AC and chondroitinase B, respectively, Flavobacterium heparinum. Appl. Environ. Microbiol. 66, 29–35.10.1128/AEM.66.1.29-35.2000Search in Google Scholar PubMed PubMed Central

Ubogu, E.E. (2012). Translational strategies in peripheral neuroinflammation and neurovascular repair. Transl. Neurosci. 3, 373–383.10.2478/s13380-012-0039-4Search in Google Scholar PubMed PubMed Central

Vogelezang, M., Forster, U.B., Han, J., Ginsberg, M.H., and ffrench-Constant, C. (2007). Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with α4β1 integrins. BMC Neurosci. 8, 44.10.1186/1471-2202-8-44Search in Google Scholar PubMed PubMed Central

Wallquist, W., Patarroyo, M., Thams, S., Carlstedt, T., Stark, B., Cullheim, S., and Hammarberg, H. (2002). Laminin chains in rat and human peripheral nerve: distribution and regulation during development and after axonal injury. J. Comp. Neurol. 454, 284–293.10.1002/cne.10434Search in Google Scholar PubMed

Wallquist, W., Zelano, J., Plantman, S., Kaufman, S.J., Cullheim, S., and Hammarberg, H. (2004). Dorsal root ganglion neurons up-regulate the expression of laminin-associated integrins after peripheral but not central axotomy. J. Comp. Neurol. 480, 162–169.10.1002/cne.20345Search in Google Scholar PubMed

Wallquist, W., Plantman, S., Thams, S., Thyboll, J., Kortesmaa, J., Lannergren, J., Domogatskaya, A., Ogren, S.O., Risling, M., Hammarberg, H., et al. (2005). Impeded interaction between Schwann cells and axons in the absence of laminin alpha4. J. Neurosci. 25, 3692–3700.10.1523/JNEUROSCI.5225-04.2005Search in Google Scholar PubMed PubMed Central

Wang, D., Liu, X.L., Zhu, J.K., Jiang, L., Hu, J., Zhang, Y., Yang, L.M., Wang, H.G., and Yi, J.H. (2008). Bridging small-gap peripheral nerve defects using acellular nerve allograft implanted with autologous bone marrow stromal cells in primates. Brain Res. 1188, 44–53.10.1016/j.brainres.2007.09.098Search in Google Scholar PubMed

Wang, D., Liu, X.L., Zhu, J.K., Hu, J., Jiang, L., Zhang, Y., Yang, L.M., Wang, H.G., Zhu, Q.T., Yi, J.H., et al. (2010). Repairing large radial nerve defects by acellular nerve allografts seeded with autologous bone marrow stromal cells in a monkey model. J. Neurotrauma 27, 1935–1943.10.1089/neu.2010.1352Search in Google Scholar PubMed

Wang, Y., Jia, H., Li, W.Y., Tong, X.J., Liu, G.B., and Kang, S.W. (2012). Synergistic effects of bone mesenchymal stem cells and chondroitinase ABC on nerve regeneration after acellular nerve allograft in rats. Cell. Mol. Neurobiol. 32, 361–371.10.1007/s10571-011-9764-4Search in Google Scholar PubMed

White, E.S., and Muro, A.F. (2011). Fibronectin splice variants: understanding their multiple roles in health and disease using engineered mouse models. IUBMB Life 63, 538–546.10.1002/iub.493Search in Google Scholar PubMed

Yang, C.R., and Chen, J.D. (2012). Preparation and biological evaluation of chitosan-collagen-icariin composite scaffolds for neuronal regeneration. Neurol. Sci. 34, 941–947.10.1007/s10072-012-1165-zSearch in Google Scholar PubMed

Yao, C.C., Yao, P., Wu, H., and Zha, Z.G. (2007). Absorbable collagen sponge combined with recombinant human basic fibroblast growth factor promotes nerve regeneration in rat sciatic nerve. J. Mater. Sci. Mater. Med. 18, 1969–1972.10.1007/s10856-007-3093-7Search in Google Scholar PubMed

Yao, L., de Ruiter, G.C., Wang, H., Knight, A.M., Spinner, R.J., Yaszemski, M.J., Windebank, A.J., and Pandit, A. (2010a). Controlling dispersion of axonal regeneration using a multichannel collagen nerve conduit. Biomaterials 31, 5789–5797.10.1016/j.biomaterials.2010.03.081Search in Google Scholar PubMed

Yao, L., Billiar, K.L., Windebank, A.J., and Pandit, A. (2010b). Multichanneled collagen conduits for peripheral nerve regeneration: design, fabrication, and characterization. Tissue Eng. 16, 1585–1596.10.1089/ten.tec.2010.0152Search in Google Scholar

Yu, H., Peng, J., Guo, Q., Zhang, L., Li, Z., Zhao, B., Sui, X., Wang, Y., Xu, W., and Lu, S. (2009). Improvement of peripheral nerve regeneration in acellular nerve grafts with local release of nerve growth factor. Microsurgery 29, 330–336.10.1002/micr.20635Search in Google Scholar PubMed

Yu, W., Zhao, W., Zhu, C., Zhang, X., Ye, D., Zhang, W., Zhou, Y., Jiang, X., and Zhang, Z. (2011). Sciatic nerve regeneration in rats by a promising electrospun collagen/poly(epsilon-caprolactone) nerve conduit with tailored degradation rate. BMC Neurosci. 12, 68.10.1186/1471-2202-12-68Search in Google Scholar

Yurchenco, P.D., Smirnov, S., and Mathus, T. (2002). Analysis of basement membrane self-assembly and cellular interactions with native and recombinant glycoproteins. Methods Cell Biol. 69, 111–144.10.1016/S0091-679X(02)69010-7Search in Google Scholar

Zhang, H., Wei, Y.T., Tsang, K.S., Sun, C.R., Li, J., Huang, H., Cui, F.Z., and An, Y.H. (2008). Implantation of neural stem cells embedded in hyaluronic acid and collagen composite conduit promotes regeneration in a rabbit facial nerve injury model. J. Transl. Med. 6, 67.10.1186/1479-5876-6-67Search in Google Scholar

Zhang, L., Cao, R., Zhu, Y., Feng, G., Zhang, X., and Hhuang, F. (2010a). Repair of the peripheral nerve defect with the combination of allogeneic nerve and autologous neuroma. Turk. Neurosurg. 20, 470–479Search in Google Scholar

Zhang, Y., Luo, H., Zhang, Z., Lu, Y., Huang, X., Yang, L., Xu, J., Yang, W., Fan, X., Du, B., et al. (2010b). A nerve graft constructed with xenogeneic acellular nerve matrix and autologous adipose-derived mesenchymal stem cells. Biomaterials 31, 5312–5324.10.1016/j.biomaterials.2010.03.029Search in Google Scholar

Zhao, Z., Wang, Y., Peng, J., Ren, Z., Zhan, S., Liu, Y., Zhao, B., Zhao, Q., Zhang, L., Guo, Q., et al. (2011). Repair of nerve defect with acellular nerve graft supplemented by bone marrow stromal cells in mice. Microsurgery 31, 388–394.10.1002/micr.20882Search in Google Scholar

Zuo, J., Hernandez, Y.J., and Muir, D. (1997). Chondroitin sulfate proteoglycan with neurite-inhibiting activity is up-regulated following peripheral nerve injury. J. Neurobiol. 34, 41–54.10.1002/(SICI)1097-4695(199801)34:1<41::AID-NEU4>3.0.CO;2-CSearch in Google Scholar

Zuo, J., Ferguson, T.A., Hernandez, Y.J., Stetler-Stevenson, W.G., and Muir, D. (1998). Neuronal matrix metalloproteinase-2 degrades and inactivates a neurite-inhibiting chondroitin sulfate proteoglycan. J. Neurosci. 18, 5203–5211.10.1523/JNEUROSCI.18-14-05203.1998Search in Google Scholar

Zuo, J., Neubauer, D., Graham, J., Krekoski, C.A., Ferguson, T.A., and Muir, D. (2002) Regeneration of axons after nerve transection repair is enhanced by degradation of chondroitin sulfate proteoglycan. Exp. Neurol. 176, 221–228.Search in Google Scholar