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Global research trends and emerging hotspots in acute high altitude illness: a bibliometric analysis and review (1937–2024)

  • Yongjiang Zhou , Hanyu Ding , Hongyin Liang , Yiwen Zhao , Jiajie Feng , Kexin Jiang and Ruiwu Dai EMAIL logo
Published/Copyright: March 31, 2025
Reviews on Environmental Health
From the journal Reviews on Environmental Health Volume 40 Issue 3

Abstract

Introduction

Acute High Altitude Illness (AHAI) includes conditions such as Acute Mountain Sickness (AMS), High Altitude Cerebral Edema (HACE), and High Altitude Pulmonary Edema (HAPE), which result from rapid ascent to altitudes exceeding 2,500 m. Although interest in AHAI research has been growing, a systematic and comprehensive analysis of global research trends remains lacking.

Content

A total of 3,214 articles and reviews published from 1937 to 2024 were retrieved from the Web of Science Core Collection. Bibliometric tools, including CiteSpace and VOSviewer, were applied to thoroughly assess publication trends, collaborative networks among authors, institutional contributions, and keyword co-occurrence patterns. The dataset represents the contributions of over 11,758 authors across 86 countries and 3,378 institutions, reflecting the significant growth of this research domain.

Summary and Outlook

Our findings highlight the increasing scholarly attention to AHAI research, with the United States leading in publication numbers. Emerging research themes include cellular activation, oxidative stress, risk factors, and hypobaric hypoxia. This is the first systematic bibliometric review of AHAI literature, offering a detailed roadmap of research hotspots, potential collaborations, and key future directions. These findings provide a valuable reference for researchers aiming to explore gaps and build on the existing knowledge in high-altitude medicine.

Keywords: acute high altitude illness; acute mountain sickness; bibliometric analysis; high-altitude cerebral edema; high-altitude pulmonary edema; research hotspots
Corresponding author: Ruiwu Dai, Department of General Surgery, Affiliated Hospital of Southwest Medical University, No.1, Section 1, Xianglin Road, Longmatan District, Sichuan, 646000, China; and General Surgery Center, General Hospital of Western Theater Command, No. 270, Rongdu Rd, Jinniu District, Sichuan, 610083, China, E-mail:

Funding source: The study was supported by Hospital Management of the General Hospital of Western Theater Command

Award Identifier / Grant number: 2024-YGLC-A01

  1. Research ethics: Not applicable.

  2. Informed consent: Not applicable.

  3. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  4. Use of Large Language Models, AI and Machine Learning Tools: The authors would like to acknowledge the use of ChatGPT, an AI language model developed by OpenAI, for providing editorial assistance in improving the English language of this manuscript. It is important to note that the assistance provided by ChatGPT was limited to language editing, while all original content, ideas, data analysis, results, and discussions were solely generated by the authors. After using this tool, the authors reviewed and edited the content as needed and take full responsibility for the content of the publication.

  5. Conflict of interest: Authors state no conflict of interest.

  6. Research funding: The study was supported by Hospital Management of the General Hospital of Western Theater Command (2024-YGLC-A01).

  7. Data availability: Not applicable.

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Supplementary Material

This article contains supplementary material (https://doi.org/10.1515/reveh-2024-0144).

Received: 2024-11-19
Accepted: 2025-02-21
Published Online: 2025-03-31
Published in Print: 2025-09-25

© 2025 Walter de Gruyter GmbH, Berlin/Boston

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  6. Global research trends and emerging hotspots in acute high altitude illness: a bibliometric analysis and review (1937–2024)
  7. Sustainable materials and energy from pine needle waste – a review
  8. Interrelation between prenatal mercury-selenium exposure and glutathione gene polymorphism: impact on growth and development in children
  9. Connecting the dots: environmental pollution and Autism Spectrum Disorder
  10. Phthalates, bisphenols and per-and polyfluoroalkyl substances migration from food packaging into food: a systematic review
  11. Dietary intake of dioxins and cancer – where do we stand?
  12. Unfinished business: formaldehyde exposure from uniforms and the case for U.S. textile regulation
  13. A mini-review on the health risks associated with sodium p-perfluorous nonenoxybenzene sulfonate exposure
  14. Maternal exposure to particulate matter and nitrogen oxides during pregnancy and attention deficit hyperactivity disorder in offspring: a systematic review and meta-analysis
https://doi.org/10.1515/reveh-2024-0144
Keywords for this article
acute high altitude illness; acute mountain sickness; bibliometric analysis; high-altitude cerebral edema; high-altitude pulmonary edema; research hotspots

Articles in the same Issue

  1. Frontmatter
  2. Reviews
  3. The association of particulate matter PM2.5 and nitrogen oxides from ambient air pollution and mental health of children and young adults- a systematic review
  4. Plant endophytic bacteria reduce phthalates accumulation in soil-crop-body system: a review
  5. A review in analytical progress for house dust mite allergens
  6. Global research trends and emerging hotspots in acute high altitude illness: a bibliometric analysis and review (1937–2024)
  7. Sustainable materials and energy from pine needle waste – a review
  8. Interrelation between prenatal mercury-selenium exposure and glutathione gene polymorphism: impact on growth and development in children
  9. Connecting the dots: environmental pollution and Autism Spectrum Disorder
  10. Phthalates, bisphenols and per-and polyfluoroalkyl substances migration from food packaging into food: a systematic review
  11. Dietary intake of dioxins and cancer – where do we stand?
  12. Unfinished business: formaldehyde exposure from uniforms and the case for U.S. textile regulation
  13. A mini-review on the health risks associated with sodium p-perfluorous nonenoxybenzene sulfonate exposure
  14. Maternal exposure to particulate matter and nitrogen oxides during pregnancy and attention deficit hyperactivity disorder in offspring: a systematic review and meta-analysis
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