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Carbon nanomaterial-involved EMT and CSC in cancer

  • Xiaotong Yang , Gongquan Xu , Xiaolong Liu , Guiming Zhou , Bing Zhang , Fan Wang , Lingjuan Wang EMAIL logo , Bin Li EMAIL logo and Liming Li
Published/Copyright: October 7, 2021
Reviews on Environmental Health
From the journal Reviews on Environmental Health Volume 38 Issue 1

Abstract

Carbon nanomaterials (CNMs) are ubiquitous in our daily lives because of the outstanding physicochemical properties. CNMs play curial parts in industrial and medical fields, however, the risks of CNMs exposure to human health are still not fully understood. In view of, it is becoming extremely difficult to ignore the existence of the toxicity of CNMs. With the increasing exploitation of CNMs, it’s necessary to evaluate the potential impact of these materials on human health. In recent years, more and more researches have shown that CNMs are contributed to the cancer formation and metastasis after long-term exposure through epithelial-mesenchymal transition (EMT) and cancer stem cells (CSCs) which is associated with cancer progression and invasion. This review discusses CNMs properties and applications in industrial and medical fields, adverse effects on human health, especially the induction of tumor initiation and metastasis through EMT and CSCs procedure.

Keywords: applications; carbon nanomaterials; environmental pollutants; human health implications; metastasis; tumorigenesis
Corresponding authors: Bin Li, PhD, Tianjin Medical University General Hospital, Tianjin 300211, China; and State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China, E-mail: , and Lingjuan Wang, PhD, Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China, E-mail:

Xiaotong Yang, Gongquan Xu, and Xiaolong Liu contributed equally to this work.

Funding source: Incubation Fund of Tianjin Medical University General Hospital

Award Identifier / Grant number: ZYYFY2019025

  1. Research funding: This work was supported by Incubation Fund of Tianjin Medical University General Hospital (No. ZYYFY2019025).

  2. Author contributions: Xiaotong Yang, Gongquan xu, Xiaolong Liu, Guiming Zhou and Bing Zhang: wrote the manuscript. Lingjuan Wang, Bin Li and Fan Wang: supervised the project and contributed to the final manuscript. Liming Li: helped supervise the project.

  3. Competing interests: The authors declare no competing financial interest.

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Received: 2021-06-18
Accepted: 2021-09-26
Published Online: 2021-10-07
Published in Print: 2023-03-28

© 2021 Walter de Gruyter GmbH, Berlin/Boston

Articles in the same Issue

  1. Frontmatter
  2. Review Articles
  3. Carbon nanomaterial-involved EMT and CSC in cancer
  4. Electronic waste exposure and DNA damage: a systematic review and meta-analysis
  5. Risk factors for heat-related illnesses during the Hajj mass gathering: an expert review
  6. A decade of research on housing and health: a systematic literature review
  7. Exposure to toxic occupations and their association with Parkinson’s disease: a systematic review with meta-analysis
  8. Interventions of Unani medicine for maintenance of health with special reference to air quality: an evidence-based review
  9. A review of microplastic pollution in commercial fish for human consumption
  10. Prevalence and causes of unreported needle stick injuries among health care workers: a systematic review and meta-analysis
  11. “Failing kidneys in a failing planet; CKD of unknown origin”
  12. Exposure to ambient gaseous air pollutants and adult lung function: a systematic review
  13. Children’s exposure to polycyclic aromatic hydrocarbon (PAHs): a review on urinary 1-hydroxypyrene and associated health effects
  14. Neurobiological effects of urban built and natural environment on mental health: systematic review
  15. Association between food additives and prevalence of allergic reactions in children: a systematic review
  16. The radionuclides contamination in eggs as an environmental marker: a systematic review
  17. Letter to the Editor
  18. Comment on Martin L. Pall “Millimeter (MM) wave and microwave frequency radiation produce deeply penetrating effects: the biology and the physics”, Rev Environ Health, 2021
https://doi.org/10.1515/reveh-2021-0082
Keywords for this article
applications; carbon nanomaterials; environmental pollutants; human health implications; metastasis; tumorigenesis

Articles in the same Issue

  1. Frontmatter
  2. Review Articles
  3. Carbon nanomaterial-involved EMT and CSC in cancer
  4. Electronic waste exposure and DNA damage: a systematic review and meta-analysis
  5. Risk factors for heat-related illnesses during the Hajj mass gathering: an expert review
  6. A decade of research on housing and health: a systematic literature review
  7. Exposure to toxic occupations and their association with Parkinson’s disease: a systematic review with meta-analysis
  8. Interventions of Unani medicine for maintenance of health with special reference to air quality: an evidence-based review
  9. A review of microplastic pollution in commercial fish for human consumption
  10. Prevalence and causes of unreported needle stick injuries among health care workers: a systematic review and meta-analysis
  11. “Failing kidneys in a failing planet; CKD of unknown origin”
  12. Exposure to ambient gaseous air pollutants and adult lung function: a systematic review
  13. Children’s exposure to polycyclic aromatic hydrocarbon (PAHs): a review on urinary 1-hydroxypyrene and associated health effects
  14. Neurobiological effects of urban built and natural environment on mental health: systematic review
  15. Association between food additives and prevalence of allergic reactions in children: a systematic review
  16. The radionuclides contamination in eggs as an environmental marker: a systematic review
  17. Letter to the Editor
  18. Comment on Martin L. Pall “Millimeter (MM) wave and microwave frequency radiation produce deeply penetrating effects: the biology and the physics”, Rev Environ Health, 2021
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