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Triterpenoids of antibacterial extracts from the leaves of Bersama abyssinica Fresen (Francoaceae)

  • Danielle Sinkam Gozo , Calixte Tonbou and Jean Momeni ORCID logo EMAIL logo
Published/Copyright: April 5, 2023
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Abstract

Phytochemical screening of the three extracts (acetone, ethanol and methanol) from Bersama abyssinica leaves revealed the presence of triterpenes, phenolic compounds and coumarins. The evaluation of the total phenolic content was achieved using the method of Folin–Ciocalteu allowed us to say that the acetone extract has the highest content of 41.73 mg EAG/g EX. Fractionation of this extract led to the isolation of two triterpenoids, namely ursolic acid (compound BE1) and its glucoside (compound BE2). Evaluation of antibacterial activity was carried out on three bacterial strains: Escherichia coli, Staphylococcus aureus and Clostridium perfringens using the method of diffusion in a solid medium. Results indicated that the three strains were sensitive to all extracts. Three strains were sensitive to the BE1 and two strains (E. coli and S. aureus) to the BE2. These results may justify the traditional use of parts of B. abyssinica in the treatment of some intestinal diseases.


Corresponding author: Jean Momeni, Laboratory of Organic Chemistry and Applications, Department of Chemistry, Faculty of Science, University of Ngaoundere, P.O. Box 454, Ngaoundere, Cameroon, E-mail:

Acknowledgements

Our thanks go to the head of the Laboratory of Microbiology and Food Biotechnology of the National Advanced School of Agro-Industrial Sciences (ENSAI), University of Ngaoundere, Cameroon.

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Conflict of interest statement: The authors declare no conflicts of interest regarding this article.

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Received: 2022-11-01
Accepted: 2023-01-31
Published Online: 2023-04-05

© 2023 Walter de Gruyter GmbH, Berlin/Boston

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