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A short review on cancer therapeutics

  • Abolanle A.A. Kayode ORCID logo EMAIL logo , Izuchukwu Emmanuel Eya and Omowumi Titilola Kayode
Published/Copyright: June 21, 2022
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Physical Sciences Reviews
From the journal Physical Sciences Reviews Volume 8 Issue 12

Abstract

Cancer as a disease has been a remarkable scourge and over the past years, advances have been made in understanding the molecular basis of carcinogenesis and combating this disease. The common traits exhibited by cancer have been individually studied to figure out its mode of action and its mechanism of survival even in the most austere conditions. The various hallmarks noted so far have been effectively studied and different therapies revolving around each hallmark are still being studied in order to find the most appropriate treatment for the different types of cancer in existence. Emerging therapies have been able to elucidate the mechanism of receptor blockage which facilitate the ability of cancer to proliferate as well as evade tumor suppressors, prevent cell death, support replicative immortality, escape immune destruction, stimulate angiogenesis, reduce cellular energetics as well as metabolism and prevent the destruction of the immune system. This life-threatening disease should be tackled aggressively with a combined therapy that involves two or more hallmarks of cancer and adverse effects of each therapy should also be considered.

Keywords: cancer; hallmark; proliferation; therapeutics
Corresponding author: Kayode A. A. Abolanle, Department of Biochemistry, School of Basic Medical Sciences, Babcock University, Ilishan-Remo, Ogun State, Nigeria, E-mail:

  1. Author contributions: All the authors have accepted responsibility for the entire content of this manuscript and approved the submission.

  2. Research funding: None declared.

  3. Conflict of interest statement: The authors declare no conflicts of interest regarding this article.

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Received: 2021-11-01
Revised: 2022-04-28
Accepted: 2022-04-28
Published Online: 2022-06-21

© 2022 Walter de Gruyter GmbH, Berlin/Boston

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https://doi.org/10.1515/psr-2021-0169
Keywords for this article
cancer; hallmark; proliferation; therapeutics

Articles in the same Issue

  1. Frontmatter
  2. Reviews
  3. Synthesis and application of organotellurium compounds
  4. Tellurium-based chemical sensors
  5. Synthesis of antiviral drugs by using carbon–carbon and carbon–heteroatom bond formation under greener conditions
  6. Green protocols for Tsuji–Trost allylation: an overview
  7. Chemistry of tellurium containing macrocycles
  8. Tellurium-induced cyclization of olefinic compounds
  9. Latest developments on the synthesis of bioactive organotellurium scaffolds
  10. Tellurium-based solar cells
  11. Semiconductor characteristics of tellurium and its implementations
  12. Tellurium based materials for nonlinear optical applications
  13. Pharmaceutical cocrystal consisting of ascorbic acid with p-aminobenzoic acid and paracetamol
  14. Carbocatalysis: a metal free green avenue towards carbon–carbon/heteroatom bond construction
  15. Physico-chemical and nutraceutical properties of Cola lepidota seed oil
  16. Cyclohexane oxidation using advanced oxidation processes with metals and metal oxides as catalysts: a review
  17. Optimization of electrolysis and carbon capture processes for sustainable production of chemicals through Power-to-X
  18. Tellurium-induced functional group activation
  19. Synthesis, characterization, and theoretical investigation of 4-chloro-6(phenylamino)-1,3,5-triazin-2-yl)asmino-4-(2,4-dichlorophenyl)thiazol-5-yl-diazenyl)phenyl as potential SARS-CoV-2 agent
  20. Process intensification and digital twin – the potential for the energy transition in process industries
  21. Photovoltaic properties of novel reactive azobenzoquinolines: experimental and theoretical investigations
  22. Accessing the environmental impact of tellurium metal
  23. Membrane-based processes in essential oils production
  24. Development of future-proof supply concepts for sector-coupled district heating systems based on scenario-analysis
  25. Educators’ reflections on the teaching and learning of the periodic table of elements at the upper secondary level: a case study
  26. Optimization of hydrogen supply from renewable electricity including cavern storage
  27. A short review on cancer therapeutics
  28. The role of bioprocess systems engineering in extracting chemicals and energy from microalgae
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  30. Characterization of lignocellulosic S. persica fibre and its composites: a review
  31. Constructing a framework for selecting natural fibres as reinforcements composites based on grey relational analysis
  32. Polybutylene succinate (PBS)/natural fiber green composites: melt blending processes and tensile properties
  33. The properties of 3D printed poly (lactic acid) (PLA)/poly (butylene-adipate-terephthalate) (PBAT) blend and oil palm empty fruit bunch (EFB) reinforced PLA/PBAT composites used in fused deposition modelling (FDM) 3D printing
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