Pregnancy and delivery outcomes of HIV infected women in Switzerland 2003–2008
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Abstract
Objective: Rates of vertical HIV transmission between mother and child are low, allowing many HIV positive women to have children with near impunity. In this study, data from the Swiss Mother and Child HIV Cohort Study were used to describe maternal characteristics and their association with pregnancy outcomes in HIV positive women.
Study design: HIV positive women were followed prospectively during their pregnancies and deliveries by anonymous questionnaires between January 2003 and October 2008. Adverse pregnancy outcomes included preterm delivery, preeclampsia and gestational diabetes mellitus.
Results: This study included 266 HIV positive women, of which 67 (25.2%) were first diagnosed with HIV during pregnancy. Thirty percent (n=80) of the women had pregnancy complications after 24 weeks of gestation. Preterm delivery was noted in 72 (27%) patients. Other complications included preeclampsia (n=7; 2.6%) and gestational diabetes (n=7; 2.6%). Older maternal age was the only risk factor associated with adverse pregnancy outcomes (adjusted odds ratio: 1.06, 95% confidence interval 1.01–1.12, P=0.02).
Conclusions: HIV positive women, especially with advanced maternal age, have high-risk pregnancies and should be monitored as in an interdisciplinary setting. The preponderance of initial HIV diagnosis during pregnancy confirms the importance of HIV screening in pregnant women.
©2010 by Walter de Gruyter Berlin New York
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- WAPM-Newsletter No 1/2010
Articles in the same Issue
- Recommendations and guidelines for perinatal practice
- Donor human milk in preterm infant feeding: evidence and recommendations
- Original articles – Obstetrics
- Pregnancy and delivery outcomes of HIV infected women in Switzerland 2003–2008
- Maternal plasma retinol binding protein 4 in acute pyelonephritis during pregnancy
- Occult inflammation and/or ischemia may be responsible for the false positivity of biochemical Down syndrome screening test
- Genital group B streptococcus carrier rate and serotype distribution in Korean pregnant women: implications for group B streptococcal disease in Korean neonates
- Pregnancy-induced antithrombin deficiency
- Cardiac output and blood flow volume redistribution during acute maternal hypoxia in fetal sheep
- Original articles – Fetus
- Epigenetic malprogramming of the insulin receptor promoter due to developmental overfeeding
- Prognosis of isolated mild to moderate fetal cerebral ventriculomegaly: a systematic review
- Original articles – Newborn
- Validation of a model to predict hospitalization due to RSV of infants born at 33–35 weeks' gestation
- Outcomes of extremely low birth weight infants with varying doses and intervals of antenatal steroid exposure
- Dependence of neonatal small and large for gestational age rates on maternal height and weight – an analysis of the German Perinatal Survey
- Clinical characteristics of nosocomial infections in neonatal intensive care unit in eastern China
- Short Communication
- Maternal complications of fetoscopic laser photocoagulation (FLP) for treatment of twin-twin transfusion syndrome (TTTS)
- Letter to the Editor
- A newborn with Down syndrome-transient myeloproliferative disorder
- Congress Calender
- Congress Calendar
- WAPM-Newsletter
- WAPM-Newsletter No 1/2010
