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Evaluating the correlation between amniotic fluid volume and estimated fetal weight in healthy pregnant women

  • Sara C.S. Souza , Katherine Kim , Alysha L.J. Dingwall-Harvey , Romina Fakhraei , Yan Liao and Laura M. Gaudet EMAIL logo
Published/Copyright: May 23, 2022

Abstract

Objectives

The establishment of cut-offs for normal amniotic fluid volume (AFV) is valuable to predict perinatal outcomes. However, the most common methods to measure AFV are not accurate enough. It is important to understand factors that may be able to increase the accuracy of the calculation of AFV cut-off values. The objective of this study was to verify the correlation between AFV and estimated fetal weight (EFW).

Methods

Records from almost 7,000 patients between 2012 and 2017 were accessed through hospital databases. The AFV measurements included in our analysis were obtained using the maximum vertical pocket technique.

Results

AFV was positively correlated with EFW in the overall, male and female samples; however, the magnitude of the association was small (0.1<r<0.3). A moderate (0.3≤r<0.5) association between AFV and EFW was found specifically during mid- to late-gestation.

Conclusions

The incorporation of EFW together with other factors (e.g., gestational age, fetus sex) may increase the accuracy of the AFV cut-offs calculation and, ultimately, reduce morbidity.


Corresponding author: Dr. Laura M. Gaudet, MSc, MD, FRCS, OMNI Research Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada; Department of Obstetrics and Gynecology, Victory 4, Kingston Health Sciences Center, 76 Stuart Street, Kingston, ON K7L 2V7, Canada; and Department of Obstetrics and Gynecology, Queen’s University, Kingston, Canada, Phone: +613-548-6072, Fax: +613-548-1330, E-mail:

Funding source: Canadian Institutes of Health Research http://dx.doi.org/10.13039/501100000024

Award Identifier / Grant number: #MFM-146444

Acknowledgments

We would like to thank Dr. Andrea Lanes, Dr. Daniel Corsi, and Natalie Rybak who provided insight and expertise that greatly assisted with the research and overall improvement in the manuscript.

  1. Research funding: This study was supported by the Canadian Institutes of Health Research (CIHR) agency (Grant #MFM-146444).

  2. Author contributions: KK, AH, RF, and LMG made substantial contributions to the conception and design of the work; AH, RF, and YL led the data acquisition and analysis; and SCSS was responsible for the interpretation of data for the work. SCSS drafted the work and KK, AH, RF, YL, and LMG revised it critically. All authors approved the final version to be published.

  3. Competing interests: Authors state no conflict of interest.

  4. Informed consent: Not applicable.

  5. Ethical approval: This study was approved by TOH Research Ethics Board (file number: 20170723-01H).

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Received: 2022-02-23
Accepted: 2022-04-25
Published Online: 2022-05-23
Published in Print: 2022-10-26

© 2022 Walter de Gruyter GmbH, Berlin/Boston

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