Startseite Emergency peripartal hysterectomy – a single-center analysis of the last 13 years at a tertiary perinatal care unit
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Emergency peripartal hysterectomy – a single-center analysis of the last 13 years at a tertiary perinatal care unit

  • Amelie de Gregorio EMAIL logo , Thomas W.P. Friedl , Christoph Scholz , Wolfgang Janni , Florian Ebner und Nikolaus de Gregorio ORCID logo
Veröffentlicht/Copyright: 4. September 2018

Abstract

Background

Peripartal hysterectomy (PH) is a challenging surgical procedure with elevated maternal morbidity.

Methods

From 2004 to 2016, 41 emergency PHs were performed at the tertiary care center of the Department of Gynecology and Obstetrics at University Hospital Ulm. In our retrospective analysis, the incidence of PH in our hospital was 12.8 per 10,000 deliveries with a maternal mortality of 2.4%. PH followed in 80.5% after cesarean section (c-section). Underlying causes/indications for PH were abnormal placentation (53.7%; n=22), uterine atony (26.8%; n=11), uterine lacerations (14.6%; n=6) and in rare cases uterine infection (4.9%; n=2). The median number of transfused products was 11 packed red blood cells (range 0–55 products), 10 fresh frozen plasma units (range 1–43) and two platelet concentrates (0–16).

Results

Loss of blood as estimated by surgeons was significantly correlated with actual transfused blood volume (P<0.001). Clinically relevant intra- and/or postoperative complications occurred in 53.7% of patients (n=22). Abnormal placentation was the leading cause for PH with an increased incidence during the last 10 years presumptively representing the elevated rate of c-sections.

Conclusion

PH goes along with increased rates of blood product transfusions independently of indication for surgery and has a high morbidity with a major complication rate of more than 50%. Prepartal assessment of risk factors like abnormal invasive placenta are crucial for reducing maternal morbidity.


Corresponding author: Dr. Amelie de Gregorio, Department of Gynecology and Obstetrics, University Hospital Ulm, Prittwitzstr. 43, 89075 Ulm, Germany, Tel.: +49 731 500 58520, Fax: +49 731 500 58526
aFlorian Ebner and Nikolaus de Gregorio: These authors contributed equally to this work.
  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Employment or leadership: None declared.

  4. Honorarium: None declared.

  5. Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

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Supplementary Material

The online version of this article offers supplementary material (https://doi.org/10.1515/jpm-2018-0149).


Received: 2018-05-01
Accepted: 2018-07-30
Published Online: 2018-09-04
Published in Print: 2019-02-25

©2019 Walter de Gruyter GmbH, Berlin/Boston

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