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Maternal and neonatal vitamin D deficiency and transient tachypnea of the newborn in full term neonates

  • Ahmed Omran EMAIL logo , Heba Mousa , Mohamed Osama Abdalla and Osama Zekry
Published/Copyright: December 21, 2017
Journal of Perinatal Medicine
From the journal Journal of Perinatal Medicine Volume 46 Issue 9

Abstract

Aim:

To investigate the association between maternal and neonatal serum 25-hydroxyvitamin D (25-OHD) levels and development of transient tachypnea of the newborn (TTN) in full term infants.

Methods:

This was a prospective case-control study carried out on 30 neonates with TTN and their mothers and 30 control neonates and their mothers. Levels of 25-OHD were measured in maternal and neonatal blood samples that were obtained in the first 12–24 h of postnatal age.

Results:

Both maternal and neonatal 25-OHD levels in the TTN group were significantly lower compared to the control group (P=0.0001). A negative correlation was observed between neonatal 25-OHD level and average hospital stay (P=0.0001).

Conclusion:

We observed that lower maternal and neonatal vitamin 25-OHD levels were associated with TTN development in full term infants.

Keywords: 25-Hydroxyvitamin D; maternal; neonatal; transient tachypnea of the newborn; vitamin D deficiency
Corresponding author: Dr. Ahmed Omran, MD, PhD, Department of Pediatrics and Neonatology, Suez Canal University, Ismailia 41522, Egypt, Tel.: +002-01272249100
aAhmed Omran and Heba Mousa: These authors contributed equally in this work.

  1. Author’s statement

  2. Conflict of interest: Authors declare that they have neither conflict of interest nor received any financial support for this work.

  3. Material and methods: Informed consent: Informed consent has been obtained from all individuals included in this study.

  4. Ethical approval: The research related to human subject use has complied with all the relevant national regulations, and institutional policies, and is in accordance with the tenets of the Helsinki Declaration, and has been approved by the authors’ institutional review board or equivalent committee.

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Received: 2017-08-31
Accepted: 2017-11-20
Published Online: 2017-12-21
Published in Print: 2018-11-27

©2018 Walter de Gruyter GmbH, Berlin/Boston

Articles in the same Issue

  1. Frontmatter
  2. Editorial
  3. Fetal anomalies – From prenatal diagnosis to therapy
  4. Corner of Academy
  5. The first trimester aneuploidy biochemical markers in IVF/ICSI patients have no additional benefit compared to spontaneous conceptions in the prediction of pregnancy complications
  6. Research articles – Obstetrics
  7. Assessment of strain and dyssynchrony in normal fetuses using speckle tracking echocardiography – comparison of three different ultrasound probes
  8. Inborn errors of metabolism in a cohort of pregnancies with non-immune hydrops fetalis: a single center experience
  9. Cytogenetic analysis in fetuses with late onset abnormal sonographic findings
  10. Fetal MRI, lower acceptance by women in research vs. clinical setting
  11. Neurological complications after therapy for fetal-fetal transfusion syndrome: a systematic review of the outcomes at 24 months
  12. Evaluation of management and surgical outcomes in pregnancies complicated by acute cholecystitis
  13. Pentaerythrityltetranitrate (PETN) improves utero- and feto-placental Doppler parameters in pregnancies with impaired utero-placental perfusion in mid-gestation – a secondary analysis of the PETN-pilot trial
  14. Early onset preeclampsia is associated with an elevated mean platelet volume (MPV) and a greater rise in MPV from time of booking compared with pregnant controls: results of the CAPE study
  15. Effect of maternal age, height, BMI and ethnicity on birth weight: an Italian multicenter study
  16. Risk factors and classification of stillbirth in a Middle Eastern population: a retrospective study
  17. Selective IUGR in dichorionic twins: what can Doppler assessment and growth discordancy say about neonatal outcomes?
  18. Early fetal megacystis: Is it possible to predict the prognosis in the first trimester?
  19. Research articles – Fetus
  20. A poor long-term neurological prognosis is associated with abnormal cord insertion in severe growth-restricted fetuses
  21. Birth-weight centiles and the risk of serious adverse neonatal outcomes at term
  22. Short communication
  23. Maternal and neonatal vitamin D deficiency and transient tachypnea of the newborn in full term neonates
  24. Acknowledgment
https://doi.org/10.1515/jpm-2017-0280
Keywords for this article
25-Hydroxyvitamin D; maternal; neonatal; transient tachypnea of the newborn; vitamin D deficiency

Articles in the same Issue

  1. Frontmatter
  2. Editorial
  3. Fetal anomalies – From prenatal diagnosis to therapy
  4. Corner of Academy
  5. The first trimester aneuploidy biochemical markers in IVF/ICSI patients have no additional benefit compared to spontaneous conceptions in the prediction of pregnancy complications
  6. Research articles – Obstetrics
  7. Assessment of strain and dyssynchrony in normal fetuses using speckle tracking echocardiography – comparison of three different ultrasound probes
  8. Inborn errors of metabolism in a cohort of pregnancies with non-immune hydrops fetalis: a single center experience
  9. Cytogenetic analysis in fetuses with late onset abnormal sonographic findings
  10. Fetal MRI, lower acceptance by women in research vs. clinical setting
  11. Neurological complications after therapy for fetal-fetal transfusion syndrome: a systematic review of the outcomes at 24 months
  12. Evaluation of management and surgical outcomes in pregnancies complicated by acute cholecystitis
  13. Pentaerythrityltetranitrate (PETN) improves utero- and feto-placental Doppler parameters in pregnancies with impaired utero-placental perfusion in mid-gestation – a secondary analysis of the PETN-pilot trial
  14. Early onset preeclampsia is associated with an elevated mean platelet volume (MPV) and a greater rise in MPV from time of booking compared with pregnant controls: results of the CAPE study
  15. Effect of maternal age, height, BMI and ethnicity on birth weight: an Italian multicenter study
  16. Risk factors and classification of stillbirth in a Middle Eastern population: a retrospective study
  17. Selective IUGR in dichorionic twins: what can Doppler assessment and growth discordancy say about neonatal outcomes?
  18. Early fetal megacystis: Is it possible to predict the prognosis in the first trimester?
  19. Research articles – Fetus
  20. A poor long-term neurological prognosis is associated with abnormal cord insertion in severe growth-restricted fetuses
  21. Birth-weight centiles and the risk of serious adverse neonatal outcomes at term
  22. Short communication
  23. Maternal and neonatal vitamin D deficiency and transient tachypnea of the newborn in full term neonates
  24. Acknowledgment
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