Watch out for congenital Zika syndrome in non-endemic regions
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Mohammad Zare Mehrjardi
Abstract
Zika virus (ZIKV), first discovered in 1947, is the most recent member of the TORCH family. It usually causes an asymptomatic or mildly symptomatic disease in infected adults but can lead to severe brain abnormalities in fetuses who are infected in utero by vertical transmission of the virus through the placenta. The constellation of these fetal/neonatal abnormalities is named as congenital Zika syndrome (CZS). Although horizontal transmission of ZIKV is largely dependent on the presence of the vector (i.e. Aedes mosquitoes), women residing in non-endemic areas are still at risk of acquiring the infection once they travel to an endemic region or have unprotected sexual contact with an infected male. Therefore, it is important for physicians practicing in non-endemic regions to be familiar with the clinical and neuroimaging manifestations of CZS and to consider this diagnosis as a potential etiology for congenital microcephaly and other fetal central nervous system abnormalities.
Author’s statement
Conflict of interest: Author states no conflict of interest.
Ethical approval: The research related to human subject use has complied with all the relevant national regulations, and institutional policies, and is in accordance with the tenets of the Helsinki Declaration, and has been approved by the authors’ institutional review board or equivalent committee.
References
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©2018 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Editorial
- A tribute to Ingrid Gruenberg, Managing Editor of the Journal of Perinatal Medicine and Case Reports in Perinatal Medicine
- Highlight: Intrapartum Care
- Editorial
- Intrapartum care
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- Hypercoiling of the umbilical cord in uncomplicated singleton pregnancies
- Validation of a new algorithm for the short-term variation of the fetal heart rate: an antepartum prospective study
- Relationship between various maternal conditions and lactic acid dehydrogenase activity in umbilical cord blood at birth
- The frequency and type of placental histologic lesions in term pregnancies with normal outcome
- Review article
- Clinical study of fetal neurobehavior by the KANET test
- Regular articles
- Maternal demographic factors associated with emergency caesarean section for non-reassuring foetal status
- Early usage of Bakri postpartum balloon in the management of postpartum hemorrhage: a large prospective, observational multicenter clinical study in South China
- Efficacy of inhaled nitric oxide in neonates with hypoxic respiratory failure and pulmonary hypertension: the Japanese experience
- Transfusion-associated necrotizing enterocolitis re-evaluated: a systematic review and meta-analysis
- Transfusion-associated necrotizing enterocolitis in preterm infants: an updated meta-analysis of observational data
- Commentary
- Watch out for congenital Zika syndrome in non-endemic regions
- Letters to the Editor
- Cervical pessary combined with vaginal progesterone for the prevention of spontaneous preterm birth: is the evidence sufficient?
- Reply to: Cervical pessary combined with vaginal progesterone for the prevention of spontaneous preterm birth: is evidence sufficient?
- Obituary
- Klaus Riegel (1926–2018)
Articles in the same Issue
- Frontmatter
- Editorial
- A tribute to Ingrid Gruenberg, Managing Editor of the Journal of Perinatal Medicine and Case Reports in Perinatal Medicine
- Highlight: Intrapartum Care
- Editorial
- Intrapartum care
- Highlight articles
- Trends in characteristics of women choosing contraindicated home births
- Impact factors on fetal descent rates in the active phase of labor: a retrospective cohort study
- Fetal cardiac time intervals in healthy pregnancies – an observational study by fetal ECG (Monica Healthcare System)
- Hypercoiling of the umbilical cord in uncomplicated singleton pregnancies
- Validation of a new algorithm for the short-term variation of the fetal heart rate: an antepartum prospective study
- Relationship between various maternal conditions and lactic acid dehydrogenase activity in umbilical cord blood at birth
- The frequency and type of placental histologic lesions in term pregnancies with normal outcome
- Review article
- Clinical study of fetal neurobehavior by the KANET test
- Regular articles
- Maternal demographic factors associated with emergency caesarean section for non-reassuring foetal status
- Early usage of Bakri postpartum balloon in the management of postpartum hemorrhage: a large prospective, observational multicenter clinical study in South China
- Efficacy of inhaled nitric oxide in neonates with hypoxic respiratory failure and pulmonary hypertension: the Japanese experience
- Transfusion-associated necrotizing enterocolitis re-evaluated: a systematic review and meta-analysis
- Transfusion-associated necrotizing enterocolitis in preterm infants: an updated meta-analysis of observational data
- Commentary
- Watch out for congenital Zika syndrome in non-endemic regions
- Letters to the Editor
- Cervical pessary combined with vaginal progesterone for the prevention of spontaneous preterm birth: is the evidence sufficient?
- Reply to: Cervical pessary combined with vaginal progesterone for the prevention of spontaneous preterm birth: is evidence sufficient?
- Obituary
- Klaus Riegel (1926–2018)
