Iron homeostasis after blood transfusion in stable preterm infants – an observational study

References

[1] Shafir T, Angulo-Barroso R, Jing Y, Angelilli ML, Jacobson SW, Lozoff B. Iron deficiency and infant motor development. Early Hum Dev. 2008;84:479–85.10.1016/j.earlhumdev.2007.12.009Search in Google Scholar PubMed PubMed Central

[2] Arnon S, Dolfin T, Bauer S, Regev RH, Litmanovitz I. Iron supplementation for preterm infants receiving restrictive red blood cell transfusions: reassessment of practice safety. J Perinatol. 2010;30:736–40.10.1038/jp.2010.33Search in Google Scholar PubMed

[3] Hugman A. Hepcidin: an important new regulator of iron homeostasis. Clin Lab Haematol. 2006;28:75–83.10.1111/j.1365-2257.2006.00768.xSearch in Google Scholar PubMed

[4] Nicolas G, Chauvet C, Viatte L, Danan JL, Bigard X, Devaux I, et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest. 2002;110:1037–44.10.1172/JCI0215686Search in Google Scholar

[5] Yapakci E, Ecevit A, Gokmen Z, Tarcan A, Ozbek N. Erythrocyte transfusions and serum prohepcidin levels in premature newborns with anemia of prematurity. J Pediatr Hematol Oncol. 2009;31:840–2.10.1097/MPH.0b013e3181b91667Search in Google Scholar PubMed

[6] Tiker F, Celik B, Tarcan A, Kilicdag H, Ozbek N, Urakan B. Serum pro-hepcidin levels and relationships with iron parameters in healthy preterm and term newborns. Pediatr Hematol Oncol. 2006;23:293–7.10.1080/08880010600629213Search in Google Scholar PubMed

[7] Amarilyo G, Mimouni FB, Oren A, Ochshorn Y, Ballin A, Deutsch V, et al. Prohepcidin concentrations and erythroid progenitors in cord blood of appropriate versus small for gestational age neonates. J Perinatol. 2010;30:396–8.10.1038/jp.2009.179Search in Google Scholar PubMed

[8] Müller KF, Lorenz L, Poets CF, Westerman M, Franz AR. Hepcidin concentrations in serum and urine correlate with iron homeostasis in preterm infants. J Pediatr. 2012;160:949–53.10.1016/j.jpeds.2011.12.030Search in Google Scholar PubMed

[9] Lorenz L, Muller KF, Poets C, Gordana Olbina AP, Westerman M, Franz AR. Short-term effects of blood transfusions on hepcidin in preterm infants. Neonatology 2015;108:205–10.10.1159/000437132Search in Google Scholar PubMed

[10] Fenton TR. A new growth chart for preterm babies: Babson and Benda’s chart updated with recent data and a new format. BMC Pediatr. 2003;3:13.10.1186/1471-2431-3-13Search in Google Scholar PubMed PubMed Central

[11] Ganz T, Nemeth E. Iron imports IV: hepcidin and regulation of body iron metabolism. Am J Physiol Gastrointest Liver Physiol. 2006;290:G199–203.10.1152/ajpgi.00412.2005Search in Google Scholar PubMed

[12] Nemeth E, Ganz T. Hepcidin and iron-loading anemias. Haematologica 2006;91:727–32.Search in Google Scholar

[13] Kim A, Nemeth E. New insights into iron regulation and erythropoiesis. Curr Opin Hematol. 2015;22:199–205.10.1097/MOH.0000000000000132Search in Google Scholar PubMed PubMed Central

[14] Young MF, Glahn RP, Ariza-Nieto M, Inglis J, lbina G, Westerman M, et al. Serum hepcidin is significantly associated with iron absorption from food and supplemental sources in healthy young women. Am J Clin Nutr. 2009;89:533–8.10.3945/ajcn.2008.26589Search in Google Scholar PubMed

[15] Dallalio G, Fleury T, Means RT. Serum hepcidin in clinical specimens. Br J Haematol. 2003;122:996–1000.10.1046/j.1365-2141.2003.04516.xSearch in Google Scholar PubMed

[16] Pramatarova T, Yarakova N, Sluncheva B, Hitrova S, Radulova P, Emilova Z. Blood transfusions suppress erythropoiesis in anemia of prematurity. Akush Ginekol (Sofia) 2013;52:42–6.Search in Google Scholar

[17] Briana DD, Boutsikou T, Baka S, Boutsikou M, Stamati L, Hassiakos D, et al. Perinatal role of hepcidin and iron homeostasis in full-term intrauterine growth-restricted infants. Eur J Haematol. 2013;90:37–44.10.1111/ejh.12035Search in Google Scholar PubMed

[18] Jazayeri A, Tsibris JC, Spellacy WN. Fetal erythropoietin levels in growth-restricted and appropriately grown neonates with and without abnormal fetal heart rate tracings: a comparison with cord blood gases and Apgar scores. J Perinatol. 1999;19:255–9.10.1038/sj.jp.7200158Search in Google Scholar PubMed

[19] Lorenz L, Herbst J, Engel C, Peter A, Abele H, Poets CF, et al. Gestational age-specific reference ranges of hepcidin in cord blood. Neonatology 2014;106:133–9.10.1159/000360072Search in Google Scholar PubMed

[20] Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004;113:1271–6.10.1172/JCI200420945Search in Google Scholar