Reference values of nuchal translucency thickness in a Brazilian population sample: experience from a single center
-
Edward Araujo Júnior
,
Claudio Rodrigues Pires
Abstract
Objective: To determine the reference values of nuchal translucency (NT) thickness at 11–14 weeks of gestation in a sample of the Brazilian population.
Methods: A retrospective cross-sectional study was carried out with singleton gestations and fetuses with a crown-rump length (CRL) of 45–84 mm. NT thickness was performed according to the guidelines of the Fetal Medicine Foundation (FMF), London, UK. To evaluate the correlation between NT thickness and gestational age (GA), polynomial equations were calculated, with determination coefficient (R2) adjustments, as proposed by Altman-Chitty.
Results: A total of 1420 pregnancies were assessed. The mean of the gestational age was 12.69±0.78 weeks. The mean maternal age was 28.78±6.81 years. The mean NT thickness (mm) for the CRL intervals of 45├50; 50├55; 55├60; 60├65; 65├70; 70├75; 75├80; 80├85 was 1.30±0.74; 1.34±0.60; 1.48±0.48; 1.56±0.68; 1.71±0.67; 1.78±0.69; 1.67±0.43; 1.67±0.58; respectively. The following second-order equation best represented the correlation between NT thickness and GA: NT=–1.2570+0.0765×GA–0.0005×GA2 (R2=0.05).
Conclusion: The reference values for NT thickness were determined for a sample of the Brazilian population. Further studies are required to evaluate the real need for including these values in first-trimester screening for chromosomal defects in Brazil.
References
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The authors stated that there are no conflicts of interest regarding the publication of this article.
©2014 by Walter de Gruyter Berlin Boston
Artikel in diesem Heft
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Artikel in diesem Heft
- frontmatter
- Review articles
- Evaluation of the role of first-trimester obstetric ultrasound in the detection of major anomalies: a systematic review
- Austrian Newborn Screening Program: a perspective of five decades
- Original articles – Obstetrics
- Cervical strain determined by ultrasound elastography and its association with spontaneous preterm delivery
- Risk factors for unfavorable pregnancy outcome in women with adverse childhood experiences
- Peroxisome proliferator-activated receptor-gamma (PPARγ) is down regulated in trophoblast cells of gestational diabetes mellitus (GDM) and in trophoblast tumour cells BeWo in vitro after stimulation with PPARγ agonists
- Premature rupture of membranes at term in low risk women: how long should we wait in the “latent phase”?
- Ferrous bisglycinate 25 mg iron is as effective as ferrous sulfate 50 mg iron in the prophylaxis of iron deficiency and anemia during pregnancy in a randomized trial
- Neonatal serum magnesium concentrations are determined by total maternal dose of magnesium sulfate administered for neuroprotection
- Labor induction in nulliparous women with an unfavorable cervix: double balloon catheter versus dinoprostone
- Peripartum thromboprophylaxis before and after implementation of a uniform heparin protocol
- Original articles – Fetus
- Impact of sex on perinatal mortality and morbidity in twins
- Opinion paper
- Preeclampsia is caused by continuous sympathetic center excitation due to an enlarged pregnant uterus
- Original articles – Newborn
- Practical application of kangaroo mother care in preterm infants: clinical characteristics and safety of kangaroo mother care
- Survival and neonatal morbidity among extremely preterm born infants in relation to gestational age based on the last menstrual period or ultrasonographic examination
- Short communication
- Reference values of nuchal translucency thickness in a Brazilian population sample: experience from a single center
- Letters to the Editor
- Hepatic rupture: a rare but serious complication of HELLP syndrome
- Reply
- Reply to: hepatic rupture – a rare but serious complication of HELLP syndrome
- Congress Calendar
- Congress Calendar
