Effect of maternal body mass index on oxytocin treatment for arrest of dilatation1)
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Shelly Soni
Abstract
To determine whether the effectiveness of oxytocin treatment of arrest of dilatation differed in obese compared to lean women, we did a retrospective analysis of 118 subjects in spontaneous labor whose arrest of dilatation was treated with oxytocin. Cases were stratified by maternal body mass index (BMI): Group A, <25 kg/m2; Group B, 25.0–29.9 kg/m2; Group C, 30.0–34.9 kg/m2; and Group D, ≥35 kg/m2. Groups were comparable in maternal age, parity, gestational age, birth weight, and the frequency of infection. Full dilatation was reached in about 90% of Group A and B, 72% of Group C, and 39% of Group D, the most obese women (P<0.001). The cesarean rate was directly related to maternal BMI, 11.4%, 22.9%, 34.3%, and 69.6% in Groups A through D, respectively (P<0.001). Significantly more oxytocin was used in group D than in the other groups during the first 3h of infusion in attempting to overcome the arrest (P=0.003). We conclude that oxytocin treatment of arrest of dilatation was less effective in obese than in lean women. This effect was most prominent in women with a BMI >35 kg/m2, who were, despite having received more oxytocin than those in the leaner groups, less than half as likely to attain full dilatation and more than twice as likely to deliver by cesarean.
- 1)
This paper was presented in abstract form at the Annual Clinical Meeting of the American Congress of Obstetricians and Gynecologists, San Diego, CA, May 7, 2012.
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The authors stated that there are no conflicts of interest regarding the publication of this article.
©2013 by Walter de Gruyter Berlin Boston
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Articles in the same Issue
- Masthead
- Masthead
- Review Article
- Is 5-methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects?
- Original Articles – Obstetrics
- Differences and similarities in the transcriptional profile of peripheral whole blood in early and late-onset preeclampsia: insights into the molecular basis of the phenotype of preeclampsiaa
- The correlation of ultrasonographic placental architecture with placental histology in the low-risk primigravid population
- The course of angiogenic factors in early- vs. late-onset preeclampsia and HELLP syndrome
- Effect of maternal body mass index on oxytocin treatment for arrest of dilatation1)
- Maternal weight gain in women with gestational diabetes mellitus
- Clinical risk factors for complete and partial placental retention – a case-control study
- Diagnostic problems in case of twin pregnancies: US vs. MRI study
- Subsequent pregnancy after stillbirth: obstetrical and medical risks
- MTHFR C677T polymorphism, folate, vitamin B12 and homocysteine in recurrent pregnancy losses: a case control study among north Indian women
- Acupuncture and/or sweeping of the fetal membranes before induction of labor: a prospective, randomized, controlled trial
- First trimester maternal serum placental protein 13 levels in singleton vs. twin pregnancies with and without severe pre-eclampsia
- Relaparotomies after cesarean sections: risk factors, indications, and management
- The impact of route of anesthesia on maternal and fetal ischemia modified albumin levels at cesarean section: a prospective randomized study
- Infection and smoking are associated with decreased plasma concentration of the anti-aging protein, α-klothoa
- Effect of oxygen tension on bacteria-stimulated cytokine production by fetal membranes
- Original Articles – Fetus
- Is there a relationship between fetal brain function and the fetal behavioral state? A fetal MEG-study
- Original Articles – Newborn
- Infrared thermography for detailed registration of thermoregulation in premature infants
- Short Communication
- Are there gender related differences in neonatal abstinence syndrome following exposure to buprenorphine during pregnancy?
- Congress Calendar
- Congress Calendar
