The correlation of ultrasonographic placental architecture with placental histology in the low-risk primigravid population
-
Sharon M. Cooley
,
Jennifer C. Donnelly
Abstract
Aim: To determine the association, if any, between placental architecture findings assessed ultrasonographically at 22 and 36 weeks and placental histology.
Methods: There was prospective recruitment of 1011 low-risk primigravids from the antenatal clinic at the Rotunda Hospital, Dublin, Ireland. Ultrasound of the placenta was performed at 22 and 36 weeks and histological assessment was made of the placenta of all participants.
Results: Complete data pertaining to ultrasound and placental histology was available for 810 women (80%). Placental calcification on ultrasound in the third trimester was associated with a higher incidence of placental infarction identified following placental histology (80.0% vs. 21.5%; P=0.009: r=0.115). The placental thickness on ultrasound in the second trimester was less in cases complicated by chorioamnionitis (2.62 cm vs. 3.07 cm; P=0.039: r=–0.176). Chronic villitis was associated with a statistically significant increased incidence of antenatal placental infarction identified on ultrasound in the third trimester (10.7% vs. 1.9%; P=0.020: r=0.113). Intervillous thrombi occurred more frequently in cases with reduced placental thickness on ultrasound in the second trimester (3.0 cm vs. 3.3 cm; P=0.035: r=–0.171).
Conclusions: Antenatal ultrasound of the placenta may aid detection of placental disease, particularly in the identification of placental infarction.
We wish to acknowledge the statistical input and advice of Dr Claire Collins, PhD, and the funding and support of “The Friends of the Rotunda”, a charity that promotes and supports research within the hospital.
References
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©2013 by Walter de Gruyter Berlin Boston
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Articles in the same Issue
- Masthead
- Masthead
- Review Article
- Is 5-methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects?
- Original Articles – Obstetrics
- Differences and similarities in the transcriptional profile of peripheral whole blood in early and late-onset preeclampsia: insights into the molecular basis of the phenotype of preeclampsiaa
- The correlation of ultrasonographic placental architecture with placental histology in the low-risk primigravid population
- The course of angiogenic factors in early- vs. late-onset preeclampsia and HELLP syndrome
- Effect of maternal body mass index on oxytocin treatment for arrest of dilatation1)
- Maternal weight gain in women with gestational diabetes mellitus
- Clinical risk factors for complete and partial placental retention – a case-control study
- Diagnostic problems in case of twin pregnancies: US vs. MRI study
- Subsequent pregnancy after stillbirth: obstetrical and medical risks
- MTHFR C677T polymorphism, folate, vitamin B12 and homocysteine in recurrent pregnancy losses: a case control study among north Indian women
- Acupuncture and/or sweeping of the fetal membranes before induction of labor: a prospective, randomized, controlled trial
- First trimester maternal serum placental protein 13 levels in singleton vs. twin pregnancies with and without severe pre-eclampsia
- Relaparotomies after cesarean sections: risk factors, indications, and management
- The impact of route of anesthesia on maternal and fetal ischemia modified albumin levels at cesarean section: a prospective randomized study
- Infection and smoking are associated with decreased plasma concentration of the anti-aging protein, α-klothoa
- Effect of oxygen tension on bacteria-stimulated cytokine production by fetal membranes
- Original Articles – Fetus
- Is there a relationship between fetal brain function and the fetal behavioral state? A fetal MEG-study
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- Infrared thermography for detailed registration of thermoregulation in premature infants
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