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The relation between 25-hydroxyvitamin D with peak bone mineral density and body composition in healthy young adults
-
Annemieke M. Boot
,
Eric P. Krenning
Published/Copyright:
May 31, 2011
Abstract
Objective: The associations between peak bone mineral density (BMD) and body composition with 25 hydroxyvitamin D (25OHD) levels in healthy young adults were evaluated.
Methods: The number of participants was 464; 347 women and 117 men. The mean age was 24.3 years (range 17–31 years). BMD of the lumbar spine, total body and femoral neck (FN) and body composition were measured by dual energy X-ray absorptiometry. Volumetric BMD, bone mineral apparent density (BMAD), of the lumbar spine and FN was calculated.
Results: In females, 25OHD level was positively associated with FN BMD and BMAD (both p<0.01) and negatively with percentage body fat (p<0.001). In males, 25OHD levels had a positive association with total body BMD and lean body mass (p=0.03 and p=0.01).
Conclusions: 25OHD level is a determinant of peak BMD in both sexes. Vitamin D status was associated with body fat in females and with lean body mass in males.
Published Online: 2011-05-31
Published in Print: 2011-06-01
©2011 by Walter de Gruyter Berlin Boston
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Keywords for this article
bone mineral density;
fat mass;
insulin-like growth factor-1;
lean body mass;
vitamin D
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- Publisher's Note
- Editorial
- The damage caused by incomplete and uncontrolled medical information
- Images in Pediatric Endocrinology
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- Original Contributions
- Are adolescent weight-related problems and general well-being essentially an issue of age, gender or rather a pubertal timing issue?
- Comparison of methimazole and propylthiouracil in the management of children and adolescents with Graves’ disease: efficacy and adverse reactions during initial treatment and long-term outcome
- The effect of glucocorticoid replacement therapy on bone mineral density in children with congenital adrenal hyperplasia
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