Excess body weight and dyslipidemia at well-child visit
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Rodrigo dos Santos Lima
and
Roseli Oselka Saccardo Sarni
Abstract
Objectives
Cardiovascular diseases are the main causes of death in the world. They are associated with the presence of risk factors such as obesity and dyslipidemia. Our objectives were to verify association between body mass index (BMI) and abnormalities in children’s lipid profile evaluated during well-child visits, seeking to identify the frequency of each disorder in this population.
Methods
A cross-sectional study examined anthropometric data and laboratory results of children aged 2 to 9 (n=363) at a pediatric clinic between 2014 and 2017. Logistic and linear regression models were employed to assess associations between variables.
Results
Mean age was 6.3 ± 2.2 years; 187 (51.5 %) were male; 253 (69.7 %) were aged between 5 and 9 years old. A total of 114 (31.4 %) presented excess body weight and 53 (14.6 %) had obesity/severe obesity. Dyslipidemia was detected in 114 (34.4 %) children. Triglycerides was the most frequently altered lipid fraction (18.5 %), followed by HDL-c (16.8 %) and LDL-c (9.1 %). There was an association between hypertriglyceridemia (p=0.013) and low HDL-c (p=0.028) with obesity. BMI z-score showed a positive correlation with triglycerides (p=0.011) and a negative correlation with HDL-c (p=0.039). No association was observed between LDL-c and BMI.
Conclusions
Excess body weight and dyslipidemia were seen in one-third of evaluated children. Elevations in triglycerides concentration were correlated with increased in BMI z-score. These findings point to the importance of monitoring nutritional status in well-child visits and performing universal screening for dyslipidemia in children, regardless of BMI.
Acknowledgments
We acknowledge the teams from the clinical analysis laboratory and medical records department of the São Paulo Air Force Hospital for their support in obtaining the necessary data for this study. CAAE: 05810918.9.0000.0082.
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Research ethics: The study was approved by the Research Ethics Committee of the Centro Universitario FMABC and São Paulo Air Force Hospital´s institutional review board.
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Informed consent: Not applicable.
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Author contributions: R.S.L: conceptualization, methodology, review of medical records, data curation, formal analysis, software, original draft. R.O.S.S: methodology, review and editing. The authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Competing interests: The authors state no conflict of interest.
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Research funding: None declared.
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Data availability: The raw data can be obtained on request from the corresponding author.
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© 2023 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
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- Extremely and very preterm children who were born appropriate for gestational age show no differences in cortisol concentrations or diurnal rhythms compared to full-term children
- A prospective comparison study of subcutaneous and intramuscular testosterone injections in transgender male adolescents
- Excess body weight and dyslipidemia at well-child visit
- Body mass index evolution and ovarian function in adolescent girls who received GnRH agonist treatment for central precocious puberty or early and fast puberty
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- Expected vs. perceived effects of gender-affirming hormone therapy among transmasculine adolescents
- Developmental scores in offspring of women with subclinical hypothyroidism in pregnancy are affected by gender and thyrotropin cutoff
- Assessment of the diagnosis, treatment, and follow-up of a group of Turkish pediatric glycogen storage disease type 1b patients with varying clinical presentations and a novel mutation
- IGAm: A novel index predicting long-term survival in patients with early-diagnosed inherited metabolic disorders
- Case Report
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Articles in the same Issue
- Frontmatter
- Review
- Clinical heterogeneity and therapeutic options for idiopathic infantile hypercalcemia caused by CYP24A1 pathogenic variant
- Original Articles
- Growth hormone use in pediatric inflammatory bowel disease
- Extremely and very preterm children who were born appropriate for gestational age show no differences in cortisol concentrations or diurnal rhythms compared to full-term children
- A prospective comparison study of subcutaneous and intramuscular testosterone injections in transgender male adolescents
- Excess body weight and dyslipidemia at well-child visit
- Body mass index evolution and ovarian function in adolescent girls who received GnRH agonist treatment for central precocious puberty or early and fast puberty
- Assessment of pubertal onset and disorders of puberty in Indian children and youth with type-1 diabetes
- A different approach to the evaluation of the genotype-phenotype relationship in biotinidase deficiency: repeated measurement of biotinidase enzyme activity
- Expected vs. perceived effects of gender-affirming hormone therapy among transmasculine adolescents
- Developmental scores in offspring of women with subclinical hypothyroidism in pregnancy are affected by gender and thyrotropin cutoff
- Assessment of the diagnosis, treatment, and follow-up of a group of Turkish pediatric glycogen storage disease type 1b patients with varying clinical presentations and a novel mutation
- IGAm: A novel index predicting long-term survival in patients with early-diagnosed inherited metabolic disorders
- Case Report
- Persistent hypercalcemia mimicking hypophosphatasia after discontinuation of a ketogenic diet: a case report
