Pediatric diabetic ketoacidosis presenting with Streptococcus intermedius brain abscess
-
Judy L. Mintz
,
Morghan B. Jameson
Abstract
Objectives
Report a novel case of new-onset type 1 diabetes in a pediatric patient presenting with DKA and concurrent Streptococcus intermedius brain abscess.
Case presentation
The following case report is that of a previously healthy 12 year-old girl presenting with new-onset type 1 diabetes with mild diabetic ketoacidosis and subsequently found to have a brain abscess. Over the course of her hospital stay, she developed seizures and was found to have a 1.3 × 1.0 × 1.2 cm right frontal parasagittal mass culture-positive for S. intermedius. Neurologic symptoms were unmasked once insulin treatment was initiated and ketosis improved, supporting the relationship between therapeutic ketosis and the management of medication-refractory epilepsy.
Conclusions
This case both supports the relationship between therapeutic ketosis and the management of medication-refractory epilepsy and highlights the need to carefully consider comorbid conditions in patients with DKA and new onset neurological symptoms.
Research funding: None declared.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
Informed Consent: Informed consent was obtained from individuals included in this case report.
Ethical approval: Research involving human subjects complied with all relevant national and institutional regulations and has been approved by the authors’ Institutional Review Board or equivalent committee.
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© 2021 Walter de Gruyter GmbH, Berlin/Boston
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Articles in the same Issue
- Frontmatter
- Review Article
- Provocative growth hormone testing in children: how did we get here and where do we go now?
- Original Articles
- Mental and somatic health in university students with type 1 diabetes: new results from DiaSHoT18, a cross sectional national health and well-being survey
- Prevalence of elevated liver enzymes and their association with type 2 diabetes risk factors in children
- What is the relationship between obesity and new circadian rhythm parameters in Turkish children and adolescents? A case-control study
- Body fat distribution in trunk and legs are associated with cardiometabolic risk clustering among Chinese adolescents aged 10–18 years old
- Is overweight/obesity a risk factor for atopic allergic disease in prepubertal children? A case–control study
- Importance of individualizing treatment decisions in girls with central precocious puberty when initiating treatment after age 7 years or continuing beyond a chronological age of 10 years or a bone age of 12 years
- Blood pressure dynamics after pubertal suppression with gonadotropin-releasing hormone analogs followed by estradiol treatment in transgender female adolescents: a pilot study
- Levels of physical activity and barriers to sport participation in young people with gender dysphoria
- Serum sclerostin concentration is associated with specific adipose, muscle and bone tissue markers in lean adolescent females with increased physical activity
- Validation of a continuous measure of cardiometabolic risk among adolescents
- Clinical characteristics and molecular genetic analysis of a cohort with idiopathic congenital hypogonadism
- The genetics and clinical manifestations of patients with vitamin D dependent rickets type 1A
- Switching from conventional therapy to burosumab injection has the potential to prevent nephrocalcinosis in patients with X-linked hypophosphatemic rickets
- Case Reports
- Asymptomatic pituitary apoplexy induced by corticotropin-releasing hormone in a 14 year-old girl with Cushing’s disease
- Two patients from Turkey with a novel variant in the GM2A gene and review of the literature
- Familial hyperphosphatemic tumoral calcinosis in an unusual and usual sites and dramatic improvement with the treatment of acetazolamide, sevelamer and topical sodium thiosulfate
- Pediatric diabetic ketoacidosis presenting with Streptococcus intermedius brain abscess
