Body fat distribution in trunk and legs are associated with cardiometabolic risk clustering among Chinese adolescents aged 10–18 years old
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Qingmei Yang
Abstract
Objectives
The aim of the present study was to evaluate the association of body fat distribution with cardiometabolic risk factors clustering among Chinese adolescents.
Methods
In this cross sectional study a total of 1,175 adolescents aged 10–18 years underwent a comprehensive assessment of cardimetabolic risk factors. Body fat analysis was performed with bioelectrical impedance analysis (BIA).
Results
Individuals with the CVRFs≥1 or CVRFs≥2 had higher indices of body fat distribution such as body fat mass (BFM) compared to those with normal CVRFs (all p<0.001). The prevalence of CVRFs≥1, CVRFs≥2 increased with increasing of the quartile of BFM, TBFM, ABFM, LBFM, PBF, VFL compared to normal subjects. After adjusted for age and sex, the study indicated an linear relationship between TBFM (β = 0.693, 95% CI:0.363, 1.023), LBFM (β = −1.471, 95% CI:−2.768, −0.175) and CVRFs z-score. Logistic regression models suggested TBFM was associated with CVRFs≥1 and CVRFs≥2 by higher odds. Lower odds of LBFM was associated with CVRFs≥2.
Conclusions
The contribution of the fat mass in specific region on the cardiovascular risk factors clustering is different among adolescents. The trunk fat is associated with higher clustered cardiometabolic risk, while leg fat mass is the protective factor.
Funding source: National Science Foundation of China
Award Identifier / Grant number: 81660565
Research funding: Project supported by the National Science Foundation of China (Grant No. 81660565).
Author contribution: Study concepts: Qingmei Yang, Wenqing Ding. Study design: Qingmei Yang, Ping Ma, Hao Zhang, Rongrong Cai, Yangyang Dong, Wenqing Ding. Data collection: Qingmei Yang, Ping Ma, Hao Zhang, Rongrong Cai, Yangyang Dong, Wenqing Ding. Data analysis: Qingmei Yang. Manuscript: Qingmei Yang. Manuscript review: Qingmei Yang, Wenqing Ding.
Competing interests: The authors declare that they have no conflict of interest
Informed consent: Written informed consent was obtained before collecting materials.
Ethics approval: The study protocols were approved by the Ethics Review Committee of Ningxia Medical University (No. 2016-123).
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© 2021 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Review Article
- Provocative growth hormone testing in children: how did we get here and where do we go now?
- Original Articles
- Mental and somatic health in university students with type 1 diabetes: new results from DiaSHoT18, a cross sectional national health and well-being survey
- Prevalence of elevated liver enzymes and their association with type 2 diabetes risk factors in children
- What is the relationship between obesity and new circadian rhythm parameters in Turkish children and adolescents? A case-control study
- Body fat distribution in trunk and legs are associated with cardiometabolic risk clustering among Chinese adolescents aged 10–18 years old
- Is overweight/obesity a risk factor for atopic allergic disease in prepubertal children? A case–control study
- Importance of individualizing treatment decisions in girls with central precocious puberty when initiating treatment after age 7 years or continuing beyond a chronological age of 10 years or a bone age of 12 years
- Blood pressure dynamics after pubertal suppression with gonadotropin-releasing hormone analogs followed by estradiol treatment in transgender female adolescents: a pilot study
- Levels of physical activity and barriers to sport participation in young people with gender dysphoria
- Serum sclerostin concentration is associated with specific adipose, muscle and bone tissue markers in lean adolescent females with increased physical activity
- Validation of a continuous measure of cardiometabolic risk among adolescents
- Clinical characteristics and molecular genetic analysis of a cohort with idiopathic congenital hypogonadism
- The genetics and clinical manifestations of patients with vitamin D dependent rickets type 1A
- Switching from conventional therapy to burosumab injection has the potential to prevent nephrocalcinosis in patients with X-linked hypophosphatemic rickets
- Case Reports
- Asymptomatic pituitary apoplexy induced by corticotropin-releasing hormone in a 14 year-old girl with Cushing’s disease
- Two patients from Turkey with a novel variant in the GM2A gene and review of the literature
- Familial hyperphosphatemic tumoral calcinosis in an unusual and usual sites and dramatic improvement with the treatment of acetazolamide, sevelamer and topical sodium thiosulfate
- Pediatric diabetic ketoacidosis presenting with Streptococcus intermedius brain abscess
Articles in the same Issue
- Frontmatter
- Review Article
- Provocative growth hormone testing in children: how did we get here and where do we go now?
- Original Articles
- Mental and somatic health in university students with type 1 diabetes: new results from DiaSHoT18, a cross sectional national health and well-being survey
- Prevalence of elevated liver enzymes and their association with type 2 diabetes risk factors in children
- What is the relationship between obesity and new circadian rhythm parameters in Turkish children and adolescents? A case-control study
- Body fat distribution in trunk and legs are associated with cardiometabolic risk clustering among Chinese adolescents aged 10–18 years old
- Is overweight/obesity a risk factor for atopic allergic disease in prepubertal children? A case–control study
- Importance of individualizing treatment decisions in girls with central precocious puberty when initiating treatment after age 7 years or continuing beyond a chronological age of 10 years or a bone age of 12 years
- Blood pressure dynamics after pubertal suppression with gonadotropin-releasing hormone analogs followed by estradiol treatment in transgender female adolescents: a pilot study
- Levels of physical activity and barriers to sport participation in young people with gender dysphoria
- Serum sclerostin concentration is associated with specific adipose, muscle and bone tissue markers in lean adolescent females with increased physical activity
- Validation of a continuous measure of cardiometabolic risk among adolescents
- Clinical characteristics and molecular genetic analysis of a cohort with idiopathic congenital hypogonadism
- The genetics and clinical manifestations of patients with vitamin D dependent rickets type 1A
- Switching from conventional therapy to burosumab injection has the potential to prevent nephrocalcinosis in patients with X-linked hypophosphatemic rickets
- Case Reports
- Asymptomatic pituitary apoplexy induced by corticotropin-releasing hormone in a 14 year-old girl with Cushing’s disease
- Two patients from Turkey with a novel variant in the GM2A gene and review of the literature
- Familial hyperphosphatemic tumoral calcinosis in an unusual and usual sites and dramatic improvement with the treatment of acetazolamide, sevelamer and topical sodium thiosulfate
- Pediatric diabetic ketoacidosis presenting with Streptococcus intermedius brain abscess
