Abstract
On average, ectopic thyroids are positioned in the embryotic decent path that emerges as a lingual thyroid or a thyroglossal duct cyst. It is uncommon for ectopic thyroids to be located in the lateral neck, which only represents 1%–3% of all cases. Any ectopic thyroids that emerge in the posterior lateral neck in pediatric patients should be regarded as an extremely unique case. We report a 13-year-old boy with ectopic thyroid tissue in the cervical lymph nodes with orthotopic euthyroid thyroid. The masses were located on the left posterior triangle area, which were confirmed as histologic benign thyroid tissue without any malignancy in the head and neck. Authors suggest that this case supports the benign lymphatic transport theory of lateral ectopic thyroid.
References
1. Batsakis JG, El-Naggar AK, Luna MA. Thyroid gland ectopias. Ann Otol Rhinol Laryngol 1996;105:996–1000.10.1177/000348949610501212Suche in Google Scholar
2. Mussak EN, Kacker A. Surgical and medical management of midline ectopic thyroid. Otolaryngol Head Neck Surg 2007;136:870–2.10.1016/j.otohns.2007.01.008Suche in Google Scholar
3. Prado H, Prado A, Castillo B. Lateral ectopic thyroid: a case diagnosed preoperatively. Ear Nose Throat J 2012;91:E14–8.10.1177/014556131209100417Suche in Google Scholar
4. De Felice M, Di Lauro R. Thyroid development and its disorders: genetics and molecular mechanisms. Endocr Rev 2004;25:722–46.10.1210/er.2003-0028Suche in Google Scholar
5. Chanin LR, Greenberg LM. Pediatric upper airway obstruction due to ectopic thyroid: classification and case reports. Laryngoscope 1988;98:422–7.Suche in Google Scholar
6. Huang TS, Chen HY. Dual thyroid ectopia with a normally located pretracheal thyroid gland: case report and literature review. Head Neck 2007;29:885–8.10.1002/hed.20604Suche in Google Scholar
7. Feller KU, Mavros A, Gaertner HJ. Ectopic submandibular thyroid tissue with a coexisting active and normally located thyroid gland: case report and review of literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;90:618–23.10.1067/moe.2000.108804Suche in Google Scholar
8. Nicastri AD, Foote FW Jr, Frazell EL. Benign thyroid inclusions in cervical lymph nodes. J Am Med Assoc 1965;194:1–4.10.1001/jama.1965.03090140009001Suche in Google Scholar
9. Maki AC, Foster MB, Bond SJ. Lateral pediatric ectopic thyroid. Laryngoscope 2013;123:524–7.10.1002/lary.23359Suche in Google Scholar
10. Sambola-Cabrer I, Fernández-Real JM, Ricart W, Barbas JF, Ollé M, et al. Ectopic thyroid tissue presenting as a submandibular mass. Head Neck 1996;18:87–90.10.1002/(SICI)1097-0347(199601/02)18:1<87::AID-HED11>3.0.CO;2-LSuche in Google Scholar
11. Rahbar R, Yoon MJ, Connolly LP, Robson CD, Vargas SO, et al. Lingual thyroid in children: a rare clinical entity. Laryngoscope 2008;118:1174–9.10.1097/MLG.0b013e31816f6922Suche in Google Scholar
12. Damiano A, Glickman AB, Rubin JS, Cohen AF. Ectopic thyroid tissue presenting as a midline neck mass. Int J Pediatr Otorhinolaryngol 1996;34:141–8.10.1016/0165-5876(95)01229-XSuche in Google Scholar
13. Durmaz E, Barsal E, Parlak M, Gurer I, Karaguzel G, et al. Intrathyroidal ectopic thymic tissue may mimic thyroid cancer: a case report. J Pediatr Endocrinol Metab 2012;25:997–1000.10.1515/jpem-2012-0207Suche in Google Scholar PubMed
14. Piantanida E, Compri E, Lai A, Lombardi V, Mule ID, et al. Ectopic submandibular thyroid tissue with a coexisting normally located multinodular goitre: case report and review of the literature. BMJ Case Rep. Epub 2009 Dec 3. doi: 10.1136/bcr.07.2009.2136.10.1136/bcr.07.2009.2136Suche in Google Scholar PubMed PubMed Central
©2015 by De Gruyter
Artikel in diesem Heft
- Frontmatter
- Highlight: Childhood Craniopharyngioma
- Selected papers from the 3rd International Multidisciplinary Postgraduate Course, April 24–27, 2014
- Childhood craniopharyngioma – current status and recent perspectives in diagnostics and treatment
- The importance of interdisciplinary communication with patients about complex, chronic illnesses: our experiences as parents of a child with a craniopharyngioma
- Adamantinomatous craniopharyngioma: pathology, molecular genetics and mouse models
- Endocrine aspects and sequel in patients with craniopharyngioma
- Surgery for pediatric craniopharyngiomas: is less more?
- Eating behavior, weight problems and eating disorders in 101 long-term survivors of childhood-onset craniopharyngioma
- Carbohydrate-lipid profile and use of metformin with micronized fenofibrate in reducing metabolic consequences of craniopharyngioma treatment in children: single institution experience
- Effects of T3 treatment on brown adipose tissue and energy expenditure in a patient with craniopharyngioma and hypothalamic obesity
- Hypothalamic obesity after treatment for craniopharyngioma: the importance of the home environment
- Review article
- Association study of TAC3 and TACR3 gene polymorphisms with idiopathic precocious puberty in Chinese girls
- Images in pediatric endocrinology
- Intestinal invagination in diabetic ketoacidosis: case report
- Original articles
- Managing incidental findings and disclosure of results in a paediatric research cohort – the LIFE Child Study cohort
- The heterogeneity of hyperinsulinaemic hypoglycaemia in 19 patients with Beckwith-Wiedemann syndrome due to KvDMR1 hypomethylation
- Gender differences and age-related changes in body fat mass in Tibetan children and teenagers: an analysis by the bioelectrical impedance method
- A study of genes involved in adipocyte differentiation
- Initiation of growth hormone therapy in idiopathic short stature: do gender differences exist?
- The influence of puberty on vitamin D status in obese children and the possible relation between vitamin D deficiency and insulin resistance
- Growth failure associated with early neglect: pilot comparison of neglected US children and international adoptees
- Effect of growth hormone deficiency on brain MRI findings among children with growth restrictions
- Variability of lipid and lipoprotein concentrations during puberty in Brazilian boys
- Skin advanced glycation endproducts are elevated at onset of type 1 diabetes in youth
- Can optical coherence tomography predict early retinal microvascular pathology in type 1 diabetic adolescents without minimal diabetic retinopathy? A single-centre study
- Decreased levels of homoarginine and asymmetric dimethylarginine in children with type 1 diabetes: associations with cardiovascular risk factors but no effect by atorvastin
- Influence of catch-up growth on abdominal fat distribution in very low birth weight children – cohort study
- Thyrotoxic, hypokalemic periodic paralysis (THPP) in adolescents
- Pulmonary function in children with type 1 diabetes mellitus
- Identification of deletions in children with congenital hypothyroidism and thyroid dysgenesis with the use of multiplex ligation-dependent probe amplification
- Effect of l-thyroxine supplementation on infants with transient hypothyroxinemia of prematurity at 18 months of corrected age: randomized clinical trial
- Vitamin D-containing supplements for children between 1–3 years of age: Are they essential for bone health?
- Anti-Mullerian hormone levels in American girls by age and race/ethnicity
- The effect of tailoring of cornstarch intake on stature in children with glycogen storage disease type III
- Thyroid disease in Chinese girls with Turner syndrome
- Patient reports
- Pure gonadal dysgenesis (Swyer syndrome) due to microdeletion in the SRY gene: a case report
- Hypophosphatemic rickets caused by a novel splice donor site mutation and activation of two cryptic splice donor sites in the PHEX gene
- Novel heterozygous IGF1R mutation in two brothers with developing impaired glucose tolerance
- A case of pediatric ectopic thyroid in lateral lymph nodes
- Hyperostosis-hyperphosphatemia syndrome (HHS): report of two cases with a recurrent mutation and review of the literature
- Needle detachment from the Sure-T® infusion set in two young children with diabetes mellitus (DM) treated with continuous subcutaneous insulin infusion (CSII) and unexplained hyperglycaemia
- Familial dysalbuminemic hyperthyroxinemia in a 4-year-old girl with hyperactivity, palpitations and advanced dental age: how gold standard assays may be misleading
Artikel in diesem Heft
- Frontmatter
- Highlight: Childhood Craniopharyngioma
- Selected papers from the 3rd International Multidisciplinary Postgraduate Course, April 24–27, 2014
- Childhood craniopharyngioma – current status and recent perspectives in diagnostics and treatment
- The importance of interdisciplinary communication with patients about complex, chronic illnesses: our experiences as parents of a child with a craniopharyngioma
- Adamantinomatous craniopharyngioma: pathology, molecular genetics and mouse models
- Endocrine aspects and sequel in patients with craniopharyngioma
- Surgery for pediatric craniopharyngiomas: is less more?
- Eating behavior, weight problems and eating disorders in 101 long-term survivors of childhood-onset craniopharyngioma
- Carbohydrate-lipid profile and use of metformin with micronized fenofibrate in reducing metabolic consequences of craniopharyngioma treatment in children: single institution experience
- Effects of T3 treatment on brown adipose tissue and energy expenditure in a patient with craniopharyngioma and hypothalamic obesity
- Hypothalamic obesity after treatment for craniopharyngioma: the importance of the home environment
- Review article
- Association study of TAC3 and TACR3 gene polymorphisms with idiopathic precocious puberty in Chinese girls
- Images in pediatric endocrinology
- Intestinal invagination in diabetic ketoacidosis: case report
- Original articles
- Managing incidental findings and disclosure of results in a paediatric research cohort – the LIFE Child Study cohort
- The heterogeneity of hyperinsulinaemic hypoglycaemia in 19 patients with Beckwith-Wiedemann syndrome due to KvDMR1 hypomethylation
- Gender differences and age-related changes in body fat mass in Tibetan children and teenagers: an analysis by the bioelectrical impedance method
- A study of genes involved in adipocyte differentiation
- Initiation of growth hormone therapy in idiopathic short stature: do gender differences exist?
- The influence of puberty on vitamin D status in obese children and the possible relation between vitamin D deficiency and insulin resistance
- Growth failure associated with early neglect: pilot comparison of neglected US children and international adoptees
- Effect of growth hormone deficiency on brain MRI findings among children with growth restrictions
- Variability of lipid and lipoprotein concentrations during puberty in Brazilian boys
- Skin advanced glycation endproducts are elevated at onset of type 1 diabetes in youth
- Can optical coherence tomography predict early retinal microvascular pathology in type 1 diabetic adolescents without minimal diabetic retinopathy? A single-centre study
- Decreased levels of homoarginine and asymmetric dimethylarginine in children with type 1 diabetes: associations with cardiovascular risk factors but no effect by atorvastin
- Influence of catch-up growth on abdominal fat distribution in very low birth weight children – cohort study
- Thyrotoxic, hypokalemic periodic paralysis (THPP) in adolescents
- Pulmonary function in children with type 1 diabetes mellitus
- Identification of deletions in children with congenital hypothyroidism and thyroid dysgenesis with the use of multiplex ligation-dependent probe amplification
- Effect of l-thyroxine supplementation on infants with transient hypothyroxinemia of prematurity at 18 months of corrected age: randomized clinical trial
- Vitamin D-containing supplements for children between 1–3 years of age: Are they essential for bone health?
- Anti-Mullerian hormone levels in American girls by age and race/ethnicity
- The effect of tailoring of cornstarch intake on stature in children with glycogen storage disease type III
- Thyroid disease in Chinese girls with Turner syndrome
- Patient reports
- Pure gonadal dysgenesis (Swyer syndrome) due to microdeletion in the SRY gene: a case report
- Hypophosphatemic rickets caused by a novel splice donor site mutation and activation of two cryptic splice donor sites in the PHEX gene
- Novel heterozygous IGF1R mutation in two brothers with developing impaired glucose tolerance
- A case of pediatric ectopic thyroid in lateral lymph nodes
- Hyperostosis-hyperphosphatemia syndrome (HHS): report of two cases with a recurrent mutation and review of the literature
- Needle detachment from the Sure-T® infusion set in two young children with diabetes mellitus (DM) treated with continuous subcutaneous insulin infusion (CSII) and unexplained hyperglycaemia
- Familial dysalbuminemic hyperthyroxinemia in a 4-year-old girl with hyperactivity, palpitations and advanced dental age: how gold standard assays may be misleading