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The relation between salivary cortisol and the metabolic syndrome score in girls

  • Katrina D. DuBose EMAIL logo and Andrew J. McKune
Published/Copyright: April 24, 2013
Journal of Pediatric Endocrinology and Metabolism
From the journal Journal of Pediatric Endocrinology and Metabolism Volume 26 Issue 9-10

Abstract

Objective: This study investigated the relation between salivary cortisol and the metabolic syndrome (MetSyn) score in young girls.

Methods: Twenty-three girls (8.4±0.9 years) had a fasting blood draw to measure high-density lipoprotein (HDL), glucose, and triglyceride concentrations. Waist circumference and blood pressure were also measured. Saliva samples were collected three times (upon waking, 30 min post-waking, and in the evening) at home to measure cortisol levels. A continuous MetSyn score was created from blood pressure, waist circumference, HDL, triglyceride, and glucose values. Correlations examined the unadjusted associations between cortisol values, MetSyn score, and its related components. Regression analysis examined the relation between cortisol values, the MetSyn score, and its related components adjusting for breast development.

Results: The MetSyn score was not related with cortisol values; however, HDL was negatively related with 30-min post-waking, evening, and area under the curve cortisol levels. Triglycerides were positively related to the 30-min post-waking and area under the curve values. These relations existed after adjusting for breast development.

Conclusion: While the MetSyn score was not related, specific MetSyn components were related to salivary cortisol levels. Cortisol may be involved in the development of some MetSyn components.

Keywords: children; CVD risk factors; metabolic syndrome; obesity; salivary cortisol
Corresponding author: Katrina D. DuBose, PhD, FACSM, Department of Kinesiology, East Carolina University, 174 Minges Coliseum, Mail Stop 559, Greenville, NC 27858-4353, USA, Phone: +252-328-1599, Fax: +252-328-4654, E-mail: ; and East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, NC, USA

This study was funded by the Department of Kinesiology, East Carolina University (K.D. DuBose).

Conflict of interests statement:

The authors declare no conflict of interests.

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Received: 2012-12-21
Accepted: 2013-3-7
Published Online: 2013-04-24
Published in Print: 2013-10-01

©2013 by Walter de Gruyter Berlin Boston

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https://doi.org/10.1515/jpem-2012-0415
Keywords for this article
children; CVD risk factors; metabolic syndrome; obesity; salivary cortisol

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  8. Original articles
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  10. The relationship between adiposity and stature in prepubertal children with celiac disease
  11. Influence of micronutrient status and socioeconomic gradient on growth indices of 2–18-year-old Indian girls
  12. Phosphotyrosine phosphatases in GH-stimulated skin fibroblasts from children with idiopathic short stature
  13. The relation between salivary cortisol and the metabolic syndrome score in girls
  14. Association of vitamin D concentrations with adiposity indices among preadolescent children in Korea
  15. Association of serum resistin levels with metabolic syndrome and early atherosclerosis in obese Chinese children
  16. Characteristics of infants at risk of hypoglycaemia secondary to being ‘infant of a diabetic mother’
  17. Parental dyadic coping in families of children and adolescents with type 1 diabetes
  18. Pigmentary hypertrichosis and non-autoimmune insulin-dependent diabetes mellitus (PHID) syndrome is associated with severe chronic inflammation and cardiomyopathy, and represents a new monogenic autoinflammatory syndrome
  19. Effect of insulin therapy on IGF-1 level in children with new-onset type 1 diabetes mellitus: a comparison between DKA and non-DKA
  20. Mutation analysis of the SRD5A2, AR and SF-1 genes in 52 Chinese boys with hypospadias
  21. Sexual development in prepubertal obese boys: a 4-year longitudinal study
  22. Genetic diagnosis of one family with incomplete clinical data
  23. Patient reports
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