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Spontaneous resolution of pituitary apoplexy in a giant boy under 10 years old
-
Farida Chentli
,
Abderrahim Bey
Veröffentlicht/Copyright:
18. September 2012
Abstract
Aim: Pituitary gigantism is a very rare condition; the occurrence of pituitary apoplexy in children younger than 10 years old is even rarer. The aim of our study is to report this exceptional association.
Observation: A boy aged 9 years and 6 months was hospitalized for the first time in November 2011 for symptoms suggesting pituitary apoplexy. The onset of his disease was difficult to determine as his health record had been poorly maintained. On October 10, 2011, he presented to an emergency department with a sudden drop of right visual acuity with diplopia and retro-orbital headaches. An ophthalmological exam found very low visual acuity (1/20) with papillary edema. An MRI of the patient’s brain revealed a hemorrhagic pituitary process reaching the chiasma, which was compressed, especially on the right side. Thereafter, the patient’s vision improved spontaneously. Clinical examination was normal except for gigantism (+5 SD compared to the target stature). Hormonal assessment argued for mixed secretion [growth hormone (GH)=39 ng/mL, n≤5, prolactin (PRL)=470 ng/mL, n<15]. Other pituitary functions were normal. Visual acuity normalized after 2 months, and an MRI showed a spontaneous reduction of the pituitary tumor.
Conclusion: This unusual observation is a model of symptomatic pituitary apoplexy with spontaneous resolution in a boy with pituitary gigantism: phenomenon quite exceptional and worth to be reported.
Received: 2012-8-4
Accepted: 2012-8-12
Published Online: 2012-09-18
Published in Print: 2012-12-01
©2012 by Walter de Gruyter Berlin Boston
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Schlagwörter für diesen Artikel
childhood;
pituitary apoplexy;
somatolactotrop adenoma;
spontaneous reduction
Artikel in diesem Heft
- Masthead
- Masthead
- Review article
- The pros and cons of sex steroid priming in growth hormone stimulation testing
- Images in pediatric endocrinology
- Tuber sinerium hamartoma causing precocious puberty in a child
- Original articles
- Clinical features suggestive of non-classical 21-hydroxylase deficiency in children presenting with precocious pubarche
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- Clinical and genetic analysis of three Chinese patients with steroid 5α-reductase type 2 deficiency
- Apparent mineralocorticoid excess syndrome: report of one family with three affected children
- A decrease in fasting FGF19 levels is associated with the development of non-alcoholic fatty liver disease in obese adolescents
- Acanthosis nigricans predicts the clustering of metabolic syndrome components in Hispanic elementary school-aged children
- Nutritional and metabolic findings in patients with Prader-Willi syndrome diagnosed in early infancy
- Increased endothelial microparticles in obese and overweight children
- The treatment effect of diazoxide on 44 patients with congenital hyperinsulinism
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- Oxidant/antioxidant system markers and trace element levels in children with nutritional rickets
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