Management of Puberty in Constitutional Delay of Growth and Puberty
-
F. De Luca
,
J. Argente
Abstract
Constitutional delay of growth and puberty (CDGP) is the most common presenting form of short stature, but no single test can infallibly discriminate CDGP and isolated hypogonado- trophic hypogonadism. Management of puberty in CDGP aims to optimise not only growth - maintaining body proportions and improving peak bone mass without impairing growth potential - but also well-being; for example, the distress boys often suffer because of their lack of growth and pubertal progression can affect their school performance and social relationships. Typical sex steroid treatments to induce puberty in boys with CDGP include testosterone (T) enanthate, T undecanoate, mixed T esters, T transdermal patches, and oxandrolone p.o. Compared with other regimens, short-course low-dose depot T i.m. is an effective, practical, safe, well tolerated, and inexpensive regimen. Some unresolved problems in management include optimal timing and dose of sex steroid treatment, the role of GH in CDGP, and the management of CDGP in girls.
© 2016 by Walter de Gruyter Berlin/Boston
Articles in the same Issue
- Titelei
- Table of Contents
- Introduction
- Opening Remarks
- Factors Determining Final Height in Congenital Adrenal Hyperplasia
- Management of Puberty for Optimal Auxological Results in β-Thalassaemia Major
- Unresolved Problems Concerning Optimal Therapy of Puberty in Children with Chronic Renal Diseases
- Management of Puberty in Constitutional Delay of Growth and Puberty
- Turner’s Syndrome
- Idiopathic Short Stature
- Current Concepts in Tall Stature and Overgrowth Syndromes
- Optimal Therapy of Pubertal Disorders in Precocious/Early Puberty
- Unresolved Problems in Optimal Therapy of Pubertal Disorders in Oncological and Bone Marrow Transplanted Patients
- Isolated Growth Hormone Deficiency in Children and Adolescents
- Multiple Pituitary Hormone Deficiency: Management of Puberty for Optimal Auxological Results
- Concluding Remarks
Articles in the same Issue
- Titelei
- Table of Contents
- Introduction
- Opening Remarks
- Factors Determining Final Height in Congenital Adrenal Hyperplasia
- Management of Puberty for Optimal Auxological Results in β-Thalassaemia Major
- Unresolved Problems Concerning Optimal Therapy of Puberty in Children with Chronic Renal Diseases
- Management of Puberty in Constitutional Delay of Growth and Puberty
- Turner’s Syndrome
- Idiopathic Short Stature
- Current Concepts in Tall Stature and Overgrowth Syndromes
- Optimal Therapy of Pubertal Disorders in Precocious/Early Puberty
- Unresolved Problems in Optimal Therapy of Pubertal Disorders in Oncological and Bone Marrow Transplanted Patients
- Isolated Growth Hormone Deficiency in Children and Adolescents
- Multiple Pituitary Hormone Deficiency: Management of Puberty for Optimal Auxological Results
- Concluding Remarks
