The antiplaque effect of herbal mouthwash in comparison to chlorhexidine in human gingival disease: a randomized placebo controlled clinical trial

Nagesh Bhat; Ruchi Mitra; Swapnil Oza; Vinayak Kumar Mantu; Sharda Bishnoi; Mandeepsinh Gohil; Rupam Gupta

doi:10.1515/jcim-2014-0002

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The antiplaque effect of herbal mouthwash in comparison to chlorhexidine in human gingival disease: a randomized placebo controlled clinical trial

Nagesh Bhat , Ruchi Mitra , Swapnil Oza , Vinayak Kumar Mantu , Sharda Bishnoi , Mandeepsinh Gohil and Rupam Gupta

Published/Copyright: April 3, 2014

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From the journal Journal of Complementary and Integrative Medicine Volume 11 Issue 2

Abstract

Background: The aim of this study was to compare the efficacy, safety, antiplaque and antigingivitis properties of a herbal mouthwash with chlorhexidine mouthwash.

Methods: A double-blinded randomized clinical trial was conducted among 72 undergraduate students with age group 18–24 years. They were randomly divided into three mouthwash group with 24 participants in each group. Group A (herbal), Group B (chlorhexidine) and Group C (normal saline).The Turesky et al. 1970 plaque index and Loe and Silness 1963 gingival index was recorded. Student’s t-test and one-way ANOVA were used to test the significance.

Results: A statistically highly significant difference was obtained between mouthwash B and C (p=0.00) and a significant difference between mouthwash A and C (p=0.004), showing that chlorhexidine was superior to herbal mouthwash and saline. However, there was a nonsignificant difference between mouthwash A and B (p=0.435) showing that herbal and chlorhexidine mouthwash was equally effective in reducing plaque and gingivitis.

Conclusions: The efficacy of herbal mouthwash was equally effective in reducing plaque and gingivitis as compared to chlorhexidine mouthwash and may be considered as a good alternative. The chlorhexidine mouthwash was reported with many side effects which limits its acceptability and long-term use, whereas the presently tested herbal mouthwash had no side effects apart from mild burning sensation.

Keywords: plaque; herbal; chlorhexidine; plaque index; gingival index; gingivitis

Conflict of interest statement

Authors’ conflict of interest disclosure: The authors stated that there are no conflicts of interest regarding the publication of this article.

Research funding: None declared.

Employment or leadership: None declared.

Honorarium: None declared.

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Received: 2014-1-11

Accepted: 2014-3-8

Published Online: 2014-4-3

Published in Print: 2014-6-1

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Articles in the same Issue

https://doi.org/10.1515/jcim-2014-0002

Keywords for this article

plaque; herbal; chlorhexidine; plaque index; gingival index; gingivitis