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The complex relationship between physical activity and diabetes: an overview

  • Stefano Palermi , Olimpia Iacono , Felice Sirico , Michele Modestino , Carlo Ruosi , Rocco Spera and Mariarosaria De Luca EMAIL logo
Published/Copyright: September 29, 2021
Journal of Basic and Clinical Physiology and Pharmacology
From the journal Journal of Basic and Clinical Physiology and Pharmacology Volume 33 Issue 5

Abstract

Diabetes mellitus (DM) is a widespread condition, representing a challenging disease to manage. Exercise is being increasingly recommended as part of the therapeutic regimen for DM but the management of different forms of physical activity is difficult for individuals with diabetes, trainers, and physicians. Regular exercise can improve health and well-being, helping individuals to achieve their target lipid profile, body composition, cardio-respiratory fitness, and glycemic goals. People with diabetes tend to be as inactive as the general population, with a large percentage of individuals not achieving the minimum amount of recommended physical activity levels. Indeed, several barriers to exercise exist for persons with diabetes, including sports eligibility, multi-modality management of diabetic athletes, and inadequate knowledge about adequate type and intensity of exercise. The aim of the present review is to provide the current understanding of mechanisms, recommendations, and beneficial effects of different modalities of exercise for the treatment of DM.

Keywords: aerobic training; diabetes mellitus; exercise; physical activity; resistance training
Corresponding author: Mariarosaria De Luca, Department of Translational Medical Sciences, University Federico II, Via Pansini, 5, 80131, Naples, Italy, E-mail:

  1. Research funding: None declared.

  2. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Competing interests: Authors state no conflict of interest.

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Received: 2021-09-13
Accepted: 2021-09-19
Published Online: 2021-09-29

© 2021 Walter de Gruyter GmbH, Berlin/Boston

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  2. Editorial
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  4. Minireview
  5. PCSK9 and LRP6: potential combination targets to prevent and reduce atherosclerosis
  6. Reviews
  7. The complex relationship between physical activity and diabetes: an overview
  8. Methotrexate related cutaneous adverse drug reactions: a systematic literature review
  9. Long-term use of proton pump inhibitors adversely affects minerals and vitamin metabolism, bone turnover, bone mass, and bone strength
  10. An update on the physiologic changes during pregnancy and their impact on drug pharmacokinetics and pharmacogenomics
  11. Original Articles
  12. Apelin-13 protects human neuroblastoma SH-SY5Y cells against amyloid-beta induced neurotoxicity: Involvement of anti oxidant and anti apoptotic properties
  13. Are hypertensive patients with history of coronary artery disease at risk for silent lower extremity artery disease?
  14. The effect of long-term ketogenic diet on serum adiponectin and insulin-like growth factor-1 levels in mice
  15. Increase in cardioprotective SUR2A does not alter heart rate and heart rate regulation by physical activity and diurnal rhythm
  16. Effect of ascorbic acid supplementation on pulmonary functions in healthy adults: a randomized controlled pilot study
  17. Alpha2-antiplasmin deficiency affects depression and anxiety-like behavior and apoptosis induced by stress in mice
  18. Modern gold standard of cardiac output measurement – A simplified bedside measurement of individual oxygen uptake in the cath lab
  19. Electrical vestibular nerve stimulation (VeNS): a follow-up safety assessment of long-term usage
  20. Psychological impact of abnormally invasive placenta: an underestimated and hidden morbidity
  21. Limited diagnostic value of questionnaire-based pre-participation screening algorithms: a “risk-exposed” approach to sports activity
  22. Predictors of abdominal pain severity in patients with constipation-prevalent irritable bowel syndrome
https://doi.org/10.1515/jbcpp-2021-0279
Keywords for this article
aerobic training; diabetes mellitus; exercise; physical activity; resistance training

Articles in the same Issue

  1. Frontmatter
  2. Editorial
  3. Circulating tumor cells in bladder cancer: a new horizon of liquid biopsy for precision medicine
  4. Minireview
  5. PCSK9 and LRP6: potential combination targets to prevent and reduce atherosclerosis
  6. Reviews
  7. The complex relationship between physical activity and diabetes: an overview
  8. Methotrexate related cutaneous adverse drug reactions: a systematic literature review
  9. Long-term use of proton pump inhibitors adversely affects minerals and vitamin metabolism, bone turnover, bone mass, and bone strength
  10. An update on the physiologic changes during pregnancy and their impact on drug pharmacokinetics and pharmacogenomics
  11. Original Articles
  12. Apelin-13 protects human neuroblastoma SH-SY5Y cells against amyloid-beta induced neurotoxicity: Involvement of anti oxidant and anti apoptotic properties
  13. Are hypertensive patients with history of coronary artery disease at risk for silent lower extremity artery disease?
  14. The effect of long-term ketogenic diet on serum adiponectin and insulin-like growth factor-1 levels in mice
  15. Increase in cardioprotective SUR2A does not alter heart rate and heart rate regulation by physical activity and diurnal rhythm
  16. Effect of ascorbic acid supplementation on pulmonary functions in healthy adults: a randomized controlled pilot study
  17. Alpha2-antiplasmin deficiency affects depression and anxiety-like behavior and apoptosis induced by stress in mice
  18. Modern gold standard of cardiac output measurement – A simplified bedside measurement of individual oxygen uptake in the cath lab
  19. Electrical vestibular nerve stimulation (VeNS): a follow-up safety assessment of long-term usage
  20. Psychological impact of abnormally invasive placenta: an underestimated and hidden morbidity
  21. Limited diagnostic value of questionnaire-based pre-participation screening algorithms: a “risk-exposed” approach to sports activity
  22. Predictors of abdominal pain severity in patients with constipation-prevalent irritable bowel syndrome
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