Kinetics of Oxidative Deamination and Decarboxylation of L-Asparagine by Alkaline Permanganate: a Mechanistic Approach
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M.D. Saleem R. Kembhavi
Abstract
The kinetics of oxidative deamination and decarboxylation of L-asparagine (L-Aspg) by aqueous alkaline permanganate at constant ionic strength of 0.50 mol dm-3 were studied spectrophotometrically. The reaction exhibits first-order kinetics in [permanganate ion] and fractional-order dependences in [L-Aspg] and [alkali]. Initially added products such as aldehyde, ammonia and manganate have no significant effect on the rate of reaction. An increase in ionic strength and a decrease in dielectric constant of the medium increase the rate. The oxidation process in alkaline medium has shown to proceed via two paths: One a substrate dependent path, the other a substrate independent path. The constants involved in the mechanism were evaluated. There is a good agreement between observed and calculated rate constants. The activation paramaters with respect to slow step of path I and path II were calculated.
© 2014 by Walter de Gruyter Berlin/Boston
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Articles in the same Issue
- Introducing The New Co-Editor Of Inorganic Reaction Mechanisms
- Kinetic and Mechanistic Studies of Substitution Reactions of Solvated Cobalt(II), Nickel(II), Copper(II) and Zinc(II) Ions with 2,2′:6′,2″-Terpyridine and Several 2,2′:6′,2″-Terpyridine Derivatives. Evidence for the Formation of Intermediates
- Activation Volumes for a Series of Spontaneous, Acidand Base-Catalysed Aquation Reactions of Aniono trans- [Co(MeNH2)(NH3)4X]2,1+ Complexes (X=Cl-, Br-,ΝO3-,SO42-)
- Interactions of the Aminoglycoside Neamine and 2-Deoxystreptamine with Copper(II) and Zinc(II)
- Kinetics of Oxidative Deamination and Decarboxylation of L-Asparagine by Alkaline Permanganate: a Mechanistic Approach
- Kinetics of Magnesium Incorporation into Water Soluble Porphyrins
- Micellar Effect on Chromium(VI) Oxidation of D-Glucose in the Presence and Absence of Picolinic Acid in Aqueous Media: A Kinetic Study
- Kinetics of Oxidation of Antimony(III) by Tetrachloroaurate(III) in Aqueous Hydrochloric Acid Media
