Persistence of metabolic syndrome and its impact on glucose metabolism in overweight and obese children and adolescents
-
Anajás da Silva Cardoso Cantalice
,
Inês Fronteira
Abstract
Objective:
To verify the effects of metabolic syndrome (MS) and its relation to insulin resistance (IR) in children and adolescents with overweight or obesity after 24 months of follow-up.
Design:
Studies of repeated measures from April 2009 to April 2012. For both measurements, the evaluations performed were anthropometry, MS diagnosis, fasting blood glucose, glucose homeostasis model assessment (HOMA-IR), and insulin level; at a second evaluation, glycated hemoglobin (HbA1c) was used as an additional indicator of glucose metabolism alterations. Logistic regression between syndrome persistence and its components with glucose metabolism alterations was performed for each of its indicators. The SPSS version 17.0 software (95% CI) was used.
Location:
Center for Childhood Obesity, Campina Grande, Brazil.
Subjects:
Children and adolescents (n=133), aged 2–18 years, with overweight or obesity.
Results:
There was a significant decrease in MS during the study period, with persistence of the syndrome in 17.3% of the individuals. The presence of at least one alteration in glucose metabolism occurred in 45.1% of children and adolescents. The systolic and diastolic blood pressure, and the average levels of HOMA-IR showed significant decrease at the end of 24 months (p<0.01), and an elevated waist circumference (WC) remained associated with IR (p<0.01).
Conclusion:
There was observed no relationship of IR or other indicator of glycemic disorders by persistence of MS. An elevated WC remained associated with IR after controlling for the effects of the following variables: gender, age group, and other MS components.
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©2018 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Editorial
- Pre-aesculapian messages from ancient archives of Mesopotamia: the Epic of Gilgamesh and the library of Ashurbanipal
- Review
- A systematic review on critical thinking in medical education
- Original Articles
- Persistence of metabolic syndrome and its impact on glucose metabolism in overweight and obese children and adolescents
- Cross-sectional analysis of food choice frequency, sleep confounding beverages, and psychological distress predictors of sleep quality
- Adolescents’ knowledge and opinions about smoking: a qualitative study from the Jhaukhel-Duwakot Health Demographic Surveillance Site, Bhaktapur District, Nepal
- A qualitative study on how adolescent males in South India view reproductive health
- Perception of primary school teachers to school children’s mental health problems in Southwest Ethiopia
- Preparation for sexual and reproductive self-care in Iranian adolescent girls: a qualitative study
- Serum ischemia-modified albumin levels in adolescent smokers
- Perceptions and use of sources of health knowledge by young adolescents
- An exploratory study of fears among adolescent students from an urban cohort in India
- Alcohol misuse and gateway theory: a longitudinal study among adolescents in Switzerland
- Two-year prospective study of characteristics and outcome of adolescents referred to an adolescent urgent psychiatric clinic
- Screening for celiac disease in patients with eating disorders
- Clustering of behavioural risk factors for non-communicable diseases (NCDs) among rural-based adolescents in south-west Nigeria
- Knowledge, attitude, self-efficacy and estimation of frequency of condom use among Iranian students based on a crosswise model
- Depressive symptoms, hostility, and hopelessness in inner-city adolescent health clinic patients: factor structure and demographic correlates
- Short Communications
- Japanese university students’ views on lesbian, gay, bisexual, and transgender individuals based on previous encounters
- YouTube™ videos related to human papillomavirus: the need for professional communication
- Utility of salivary enzyme immunoassays for measuring estradiol and testosterone in adolescents: a pilot study
- Salivary testosterone as a potential indicator for risky behaviour associated with smoking-related peer pressure in adolescents
Articles in the same Issue
- Editorial
- Pre-aesculapian messages from ancient archives of Mesopotamia: the Epic of Gilgamesh and the library of Ashurbanipal
- Review
- A systematic review on critical thinking in medical education
- Original Articles
- Persistence of metabolic syndrome and its impact on glucose metabolism in overweight and obese children and adolescents
- Cross-sectional analysis of food choice frequency, sleep confounding beverages, and psychological distress predictors of sleep quality
- Adolescents’ knowledge and opinions about smoking: a qualitative study from the Jhaukhel-Duwakot Health Demographic Surveillance Site, Bhaktapur District, Nepal
- A qualitative study on how adolescent males in South India view reproductive health
- Perception of primary school teachers to school children’s mental health problems in Southwest Ethiopia
- Preparation for sexual and reproductive self-care in Iranian adolescent girls: a qualitative study
- Serum ischemia-modified albumin levels in adolescent smokers
- Perceptions and use of sources of health knowledge by young adolescents
- An exploratory study of fears among adolescent students from an urban cohort in India
- Alcohol misuse and gateway theory: a longitudinal study among adolescents in Switzerland
- Two-year prospective study of characteristics and outcome of adolescents referred to an adolescent urgent psychiatric clinic
- Screening for celiac disease in patients with eating disorders
- Clustering of behavioural risk factors for non-communicable diseases (NCDs) among rural-based adolescents in south-west Nigeria
- Knowledge, attitude, self-efficacy and estimation of frequency of condom use among Iranian students based on a crosswise model
- Depressive symptoms, hostility, and hopelessness in inner-city adolescent health clinic patients: factor structure and demographic correlates
- Short Communications
- Japanese university students’ views on lesbian, gay, bisexual, and transgender individuals based on previous encounters
- YouTube™ videos related to human papillomavirus: the need for professional communication
- Utility of salivary enzyme immunoassays for measuring estradiol and testosterone in adolescents: a pilot study
- Salivary testosterone as a potential indicator for risky behaviour associated with smoking-related peer pressure in adolescents
