Kallikrein-related peptidase 6 (KLK6) expression in the progression of colon adenoma to carcinoma

References

Agesen, T.H., Sveen, A., Merok, M.A., Lind, G.E., Nesbakken, A., Skotheim, R.I., and Lothe, R.A. (2012). ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer. Gut 61, 1560–1567.10.1136/gutjnl-2011-301179Suche in Google Scholar PubMed

Bayani, J. and Diamandis, E.P. (2011). The physiology and pathophysiology of human kallikrein-related peptidase 6 (KLK6). Clin. Chem. Lab. Med. 50, 211–233.Suche in Google Scholar

Borgoño, C.A., Michael, I.P., Komatsu, N., Jayakumar, A., Kapadia, R., Clayman, G.L., Sotiropoulou, G., and Diamandis, E.P. (2007). A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation. J. Biol. Chem. 282, 3640–3652.10.1074/jbc.M607567200Suche in Google Scholar PubMed

Christodoulou, S., Alexopoulou, D.K., Kontos, C.K,. Scorilas, A., and Papadopoulos, I.N. (2014). Kallikrein-related peptidase 6 (KLK6) mRNA expression is an independent prognostic tissue biomarker of poor disease-free and overall survival in colorectal adenocarcinoma. Tumour Biol. 35, 4673–4685.10.1007/s13277-014-1612-ySuche in Google Scholar PubMed

Chung, H., Hamza, M., Oikonomopoulou, K., Gratio, V., Saifeddine, M., Virca, G.D., Diamandis, E.P., Hollenberg, M.D., and Darmoul, D. (2012). Kallikrein-related peptidase signaling in colon carcinoma cells. Biol. Chem. 393, 413–420.10.1515/bc-2011-231Suche in Google Scholar PubMed

Devetzi, M., Scorilas, A., Tsiambas, E., Sameni, M., Fotiou, S., Sloane, B.F., and Talieri, M. (2009). Cathepsin B protein levels in endometrial cancer. Potential value as a tumour biomarker. Gynecol. Oncol. 112, 531–536.10.1016/j.ygyno.2008.10.030Suche in Google Scholar PubMed

Gratio, V., Beaufort, N., Seiz, L., Maier, J., Virca, G.D., Debela, M., Grebenchtchikov, N., Magdolen, V., and Darmoul, D. (2010). Kallikrein-related peptidase 4: a new activator of aberrantly expressed protease-activated receptor 1 in colon cancer cells. Am. J. Pathol. 176, 1452–1461.10.2353/ajpath.2010.090523Suche in Google Scholar PubMed PubMed Central

Henkhaus, R.S., Gerner, E.W., and Ignatenko N.A. (2008). Kallikrein 6 is a mediator of K-RAS- dependent migration of colon carcinoma cells. Biol. Chem. 389, 757–764.10.1515/BC.2008.087Suche in Google Scholar PubMed PubMed Central

Hollenberg, M.D., Oikonomopoulou, K., Hansen, K.K., Saifeddine, M., Ramachandran, R., and Diamandis, E.P. (2008). Kallikreins and proteinase-mediated signaling: proteinase-activated receptors (PARs) and the pathophysiology of inflammatory diseases and cancer. Biol. Chem. 389, 643–651.10.1515/BC.2008.077Suche in Google Scholar PubMed

Kim, J.-T., Song, E.-Y., Chung, K.-S., Kang, M.A., Kim,.J.W., Kim, S.J., Yeom, Y.I.I., Kim, J.H., Kim, K.H., and Lee, H.G. (2011). Up-regulation and clinical significance of serine protease kallikrein 6 in colon cancer. Cancer 117, 2608–2619.10.1002/cncr.25841Suche in Google Scholar PubMed

Klucky, B., Mueller, R., Vogt, I., Teurich, S., Hartenstein, B., Breuhahn, K., Flechtenmacher, C., Angel, and P., Hess, J. (2007). Kallikrein 6 induces E-Cadherin shedding and promotes cell proliferation, migration and invasion. Cancer Res. 67, 8198–8206.10.1158/0008-5472.CAN-07-0607Suche in Google Scholar PubMed

Komatsu, N., Saijoh, K., Kuk, C., Liu, A.C., Khan, S., Shirasaki, F., Takehara, K., and Diamandis. E.P. (2007). Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients. Exp. Dermatol. 16, 513–519.10.1111/j.1600-0625.2007.00562.xSuche in Google Scholar PubMed

Krenzer, S., Peterziel, H., Mauch, C., Blaber, S.I., Blaber, M., Angel, P., and Hess, J. (2011). Expression and function of the kallikrein-related peptidase 6 in the human melanoma microenvironment. J. Invest. Dermatol. 13, 2281–2288.10.1038/jid.2011.190Suche in Google Scholar PubMed PubMed Central

Lawrence, M.G., Lai, J., and Clements, A. (2010). Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus. Endocr. Rev. 31, 407–446.10.1210/er.2009-0034Suche in Google Scholar PubMed

Loessner, D., Quent, V.M., Kraemer, J., Weber, E.C., Hutmacher, D.W., Magdolen, V., and Clements, J.A. (2012). Combined expression of KLK4, KLK5, KLK6 and KLK7 by ovarian cancer cells lead to decreased adhesion and paclitaxel-induced chemoresistance. Gynecol. Oncol. 127, 569–578.10.1016/j.ygyno.2012.09.001Suche in Google Scholar PubMed

Ni, X., Zhang, W., Huang, K.C., Wang, Y., Ng, S.K., Mok, S.C., Berkowitz, R.S., and Ng, S.W. (2004). Characterisation of human kallikrein 6/protease M expression in ovarian cancer. Br. J. Cancer 91, 725–731.10.1038/sj.bjc.6602041Suche in Google Scholar PubMed PubMed Central

Ogawa, K., Utsunomiya, T., Mimori, K., Tanaka, F., Inoue, H., Nagahara, H., Murayama, S., and Mori, M. (2005). Clinical significance of human kallikrein gene 6 messenger RNA expression in colorectal cancer. Clin. Cancer Res. 11, 2889–2893.10.1158/1078-0432.CCR-04-2281Suche in Google Scholar PubMed

Ohlsson, L., Lindmark, G., Israelsson, A., Palmqvist, R., Oberg, A., Hammarstrom, M.-L., and Hammarstrom, S. (2012). Lymph node tissue kallikrein-related peptidase 6 mRNA: a progression marker for colorectal cancer. Br. J. Cancer 107, 150–157.10.1038/bjc.2012.220Suche in Google Scholar PubMed PubMed Central

Oikonomopoulou, K., Hansen, K.K., Saifeddine, M., Tea, I., Blaber, M., Blaber, S.I., Scarisbrick, I., Andrade-Gordon, P., Cottrell, G.S., Bunnett, N.W., et al. (2006). Proteinase-activated receptors, targets for kallikrein signaling. J. Biol. Chem. 281, 32095–32112.10.1074/jbc.M513138200Suche in Google Scholar PubMed

Oikonomopoulou, K., Diamandis, E.P., and Hollenberg, M.D. (2010). Kallikrein-related peptidases: proteolysis and signaling, the new frontier. Biol. Chem. 391, 299–310.10.1515/bc.2010.038Suche in Google Scholar PubMed

Olkhov-Mitsel, E., Van der Kwast, T., Kron, K.J., Ozcelik, H., Briollais, L., Massey C., Recker, F., Kwiatkowski, M., Fleshner, N.E., Diamandis, E.P., et. al. (2012). Quantitative DNA methylation analysis of genes coding for kallikrein-related peptidases 6 and 10 as biomarkers for prostate cancer. Epigenetics 7, 1037–1045.10.4161/epi.21524Suche in Google Scholar PubMed PubMed Central

Pampalakis, G., Prosnikli, E., Agalioti, T., Vlahou, A., Zoumpourlis, V., and Sotiropoulou, G. (2009). A tumor-protective role for human kallikrein-related peptidase 6 in breast cancer mediated by inhibition of epithelial to mesenchymal transition. Cancer Res. 69, 3779–3787.10.1158/0008-5472.CAN-08-1976Suche in Google Scholar PubMed

Petraki, C.D., Karavana, V.N., Skoufogiannis, P.T., Little, S.P., Howarth, D.J., Yousef, G.M., and Diamandis, E.P. (2001). The spectrum of human Kallikrein 6 (zyme/protease M/neurosin) expression in human tissues as assessed by immunohistochemistry. J. Histochem. Cytochem. 49, 1431–1441.10.1177/002215540104901111Suche in Google Scholar PubMed

Petraki, C., Dubinski W., Scorilas A., Saleh, C., Pasic MD., Komborozos V., Khalil B., Gabril M.Y., Streutker C., Diamandis E.P., et al. (2012). Evaluation and prognostic significance of human tissue kallikrein-related peptidase 6 (KLK6) in colorectal cancer. Pathol. Res. Pract. 208, 104–108.10.1016/j.prp.2011.12.010Suche in Google Scholar PubMed

Ruckert, F., Hennig, M., Petraki, C.D., Wehrum, D., Distler M., Denz A., Schroder, M., Dawelbait, G., Kalthoff, H., Saeger, H.D., et al. (2008). Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma. Br. J. Cancer 99, 1484–1492.10.1038/sj.bjc.6604717Suche in Google Scholar PubMed PubMed Central

Scarisbrick, I.A., Epstein, B., Cloud, B.A., Yoon H., Wu J., Renner, D.N., Blaber, S.I., Blaber M., Alexander G. Vandell, A.G., et al. (2011). Functional role of kallikrein 6 in regulating immune cell survival. PLoS One 6, e18376.10.1371/journal.pone.0018376Suche in Google Scholar PubMed PubMed Central

Scarisbrick, I.A., Yoon, H., Panos, M., Larson, N., Blaber, S.I., Blaber, M., and Rodriguez, M. (2012). Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis. Brain Pathol. 22, 709–722.10.1111/j.1750-3639.2012.00577.xSuche in Google Scholar PubMed PubMed Central

Sengupta, N., Gill, K.A., MacFie, T.S., Lai C.S., Suraweera, N, Mcdonald, S., and Silver, A. (2008). Management of colorectal cancer: a role for genetics in prevention and treatment? Pathol. Res. Pract. 204, 467–477.10.1016/j.prp.2008.03.003Suche in Google Scholar PubMed

Shaw, J.L. and Diamandis, E.P. (2007). Distribution of 15 human kallikreins in tissues and biological fluids. Clin. Chem. 53, 1423–1432.10.1373/clinchem.2007.088104Suche in Google Scholar PubMed

Siegel, R., DeSantis, C., Virgo, K., Mariotto, A., Smith, T., Cooper, D., Gansler T., Lerro, C., Fedewa, S., Lin, C., et al. (2012). Cancer treatment and survivorship statistics, 2012. CA Cancer J. Clin. 62, 220–241.10.3322/caac.21149Suche in Google Scholar PubMed

Sotiropoulou, G., Pampalakis, G., and Diamandis, E.P. (2009). Functional roles of human kallikrein-related peptidases. J. Biol. Chem. 284, 32989–32994.10.1074/jbc.R109.027946Suche in Google Scholar PubMed PubMed Central

Talieri, M., Li, L., Zheng, Y., Alexopoulou, D.K., Soosaipillai, A., Scorilas, A., Xynopoulos, and Diamandis, E.P. (2009). The use of kallikrein-related peptidases as adjuvant prognostic markers in colorectal cancer. Br. J. Cancer 100, 1659–1665.10.1038/sj.bjc.6605033Suche in Google Scholar PubMed PubMed Central

Talieri, M., Zoma, M., Devetzi, M., Scorila, A., and Ardavanis, A. (2012). Kallikrein-related peptidase 6 (KLK6) gene expression in intracranial tumors. Tumour Biol. 33, 1375–1383.10.1007/s13277-012-0385-4Suche in Google Scholar PubMed

Yoon, H., Radulovic, M., Wu, J., Blaber, S.I., Blaber, M., Fehlings, M.G., and Scarisbrick, I.A. (2013). Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity. J. Neurochem. 127, 283–298.10.1111/jnc.12293Suche in Google Scholar PubMed PubMed Central

Yousef, G.M., Luo, L.Y., Scherer, S.W., Sotiropoulou, G., and Diamandis, E.P. (1999). Molecular characterization of Zyme/Protease M/Neurosine (PRSS9), A hormonally regulated kallikrein-like serine protease. Genomics 62, 251–259.10.1006/geno.1999.6012Suche in Google Scholar PubMed