Functional and structural insights into astacin metallopeptidases
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F. Xavier Gomis-Rüth
F. Xavier Gomis-Rüth performed his PhD on protein crystallography under supervision of Wolfram Bode in the department of Robert Huber at the Max Planck Institute of Biochemistry (MPIB) in Martinsried (Germany) in 1992. Post doctoral stays followed at the Autonomous University of Barcelona, the MPIB, and the Molecular Biology Institute of Barcelona (IBMB) of the Spanish Research Council (CSIC), where he became a tenured research scientist in 2000. Since 2008, he has been a Research Professor at CSIC. He is the PI of the Proteolysis Lab at the Department of Structural Biology of the IBMB and author of over 100 publications in the field.
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Sergio Trillo-Muyo
Sergio Trillo-Muyo studied human biology at the Pompeu Fabra University of Barcelona, Spain, and obtained his BSc in 2006. In 2008, he obtained an MSc in Biochemistry and Molecular Biology at the Autonomous University of Barcelona in Bellaterra, Spain. He is currently a PhD student in the Proteolysis Lab at the Department of Structural Biology of the Molecular Biology Institute of Barcelona, which is part of the Spanish Research Council (CSIC).
Walter Stöcker studied chemistry and biology at the University of Munich, Germany. After receiving his doctoral degree in Munich in 1984, he was a scientific assistant at the Institute of Zoology, University of Heidelberg, Germany, and did research as a visiting scientist at the Harvard Medical School, Boston, MA, USA, and the Max Planck Institute of Biochemistry, Martinsried, Germany. He received his habilitation in biology from the University of Heidelberg in 1992, and became Associate Professor of Zoology at the University of Münster, Germany in 1996. Since 2003, he has been a full professor and chair at the University of Mainz, Germany. His research focuses on the structure and function of astacin-like zinc peptidases and their interactions in the proteolytic web.
©2012 by Walter de Gruyter Berlin Boston
Articles in the same Issue
- Masthead
- Masthead
- Guest Editorial
- No end in sight: the development of protein crystallography in Martinsried
- Highlight: No End in Sight: The Development of Protein Crystallography in Martinsried
- Functional and structural insights into astacin metallopeptidases
- β-Trefoil inhibitors – from the work of Kunitz onward
- Structural basis of the TAL effector–DNA interaction
- Nature’s way of handling a greenhouse gas: the copper-sulfur cluster of purple nitrous oxide reductase
- Rustless translation
- Structural basis of [NiFe] hydrogenase maturation by Hyp proteins
- Covalent and non-covalent reversible proteasome inhibition
- Structural origins of AGC protein kinase inhibitor selectivities: PKA as a drug discovery tool
- Structural analysis of the C-terminal domain of the spliceosomal helicase Prp22
- N-terminal acetylation of annexin A2 is required for S100A10 binding
- Withaferin A binds covalently to the N-terminal domain of annexin A2
- PhoB transcriptional activator binds hierarchically to pho box promoters
- Research Articles/Short Communications
- Protein Structure and Function
- Biochemical and functional characterization of human phospholipid scramblase 4 (hPLSCR4)
- Cell Biology and Signaling
- Dual-specificity phosphatases are targets of the Wnt/β-catenin pathway and candidate mediators of β-catenin/Ras signaling interactions
- Proteolysis
- Inhibition of Aeromonas sobria serine protease (ASP) by α2-macroglobulin
Articles in the same Issue
- Masthead
- Masthead
- Guest Editorial
- No end in sight: the development of protein crystallography in Martinsried
- Highlight: No End in Sight: The Development of Protein Crystallography in Martinsried
- Functional and structural insights into astacin metallopeptidases
- β-Trefoil inhibitors – from the work of Kunitz onward
- Structural basis of the TAL effector–DNA interaction
- Nature’s way of handling a greenhouse gas: the copper-sulfur cluster of purple nitrous oxide reductase
- Rustless translation
- Structural basis of [NiFe] hydrogenase maturation by Hyp proteins
- Covalent and non-covalent reversible proteasome inhibition
- Structural origins of AGC protein kinase inhibitor selectivities: PKA as a drug discovery tool
- Structural analysis of the C-terminal domain of the spliceosomal helicase Prp22
- N-terminal acetylation of annexin A2 is required for S100A10 binding
- Withaferin A binds covalently to the N-terminal domain of annexin A2
- PhoB transcriptional activator binds hierarchically to pho box promoters
- Research Articles/Short Communications
- Protein Structure and Function
- Biochemical and functional characterization of human phospholipid scramblase 4 (hPLSCR4)
- Cell Biology and Signaling
- Dual-specificity phosphatases are targets of the Wnt/β-catenin pathway and candidate mediators of β-catenin/Ras signaling interactions
- Proteolysis
- Inhibition of Aeromonas sobria serine protease (ASP) by α2-macroglobulin
