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Interest of systematic tomosynthesis (3D mammography) with synthetic 2D mammography in breast cancer screening

  • Mathieu Liberatore EMAIL logo , Jean-Michel Cucchi , Martine Fighiera , Anne Binet , Marie Christine Missana , Philippe Brunner , Michel Yves Mourou und Antoine Iannessi ORCID logo
Veröffentlicht/Copyright: 16. Dezember 2017

Abstract

Full field digital mammography (FFDM) is the current pillar of breast cancer screening program. However, the emerging technique digital breast tomosynthesis (DBT) has demonstrated a significant increase in the sensibility of cancer detection in several large cohort trials. DBT is particularly helpful for young patients, dense breasts and soft masses due to its ability to reduce overlapping of tissue. In such a population of women, radiologists are more confident and the recall rates are reduced together with a higher positive predictive value. To reduce the breast absorbed doses of screened women and facilitate the workflow, a synthetized two-dimensional (2D) digital mammography (sDM) is obtained from DBT to replace the FFDM. No significant differences regarding detection of anomalies have been reported with respect to FFDM. These results validate a modern strategy for breast cancer screening supported by two views of DBT with sDM. In terms of mean absorbed doses, this strategy is around 1.5 mGy/view and almost equivalent to FFDM. In Europe, major limitations to such evolution are public health policies especially agreements and reimbursement for the technique being used in organized screening.

Author Statement

  1. Research funding: Authors state no funding involved.

  2. Conflict of interest: Authors state no conflict of interest.

  3. Informed consent: Informed consent is not applicable.

  4. Ethical approval: The conducted research is not related to either human or animals use.

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Received: 2017-4-30
Accepted: 2017-8-30
Published Online: 2017-12-16

©2017 Walter de Gruyter GmbH, Berlin/Boston

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