Clinical efficacy of Majoon Falasfa and Roghan-e-Surkh in post-stroke-disability: an open labeled, pre-post analysis
-
Izhar Ahmad
,
Tanzeel Ahmad
Abstract
Objectives
Stroke is one of the leading causes of death and disability in India. The estimated adjusted prevalence rate of stroke range, 84–262/100,000 in rural and 334–424/100,000 in urban areas. A deficit in motor function affects mobility, daily activity of life. Rehabilitation is the most useful method to reduce deficit motor function. Hemiplegia (Falij), is one of the most common disability resulting from stroke has been described by Unani physicians, and they treat the disease effectively on the principle of Tanqia (evacuation) and Tadeel (alterative). Hence, a study contemplated to determine the effectiveness of Majoon Falasfa (MF) and Roghan-e-Surkh (RS) in post-stroke disability.
Methods
This trail was an open labeled, pre-post analysis, carried out at the National Institute of Unani Medicine (NIUM), on thirty (n=30) subjects of both genders, with post-stroke disability, and given MF 6 g orally with water in the morning and evening on empty stomach daily along with massage of 15 mL RS on the affected part once a day for 45 days with three follow up fortnightly (i.e. 15th, 30th, and 45th day). Patients were assessed on each follow up based on Barthel Index of Activities of Daily Living (ADL). Pre- and post-treatment values of the scale were analyzed statistically using Student’s ‘t’ test and paired Proportion test.
Results
The treatment difference as pre-post values determine with Barthel Index was found statistically highly significant (p<0.001). Safety parameters found within the normal range.
Conclusions
Finding of this trial recommended that both Unani formulations are effective in the management of post-stroke disability, and it can be used to decrease the dependency and boost the quality of life of the patients. No adverse effect was noted during the treatment of test formulations.
Acknowledgments
The authors are highly thankful to Director, National Institute of Unani Medicine, Bangalore, and K.P Suresh Biostatistician for Statistical analysis.
Research funding: None declared.
Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
Competing interests: Authors state no conflict of interest.
Informed consent: Informed consent was obtained from all individuals included in this study.
Ethical approval: Ethical clearance has been obtained from Institutional Ethics Committee (Vide IEC No: NIUM/IEC/2015–16/002/Moal/02).
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Articles in the same Issue
- Frontmatter
- Review
- Herbal approach for the management of C0VID-19: an overview
- Original Articles
- Clinically important drug–drug interactions in patients admitted to hospital with COVID-19: drug pairs, risk factors, and management
- Spinal and general anesthesia produces differential effects on oxidative stress and inflammatory cytokines in orthopedic patients
- Immunogenicity of antitumor necrosis factor therapy in patients with spondyloarthritis
- Biochip-based approach for comprehensive pharmacogenetic testing
- Clinical efficacy of Majoon Falasfa and Roghan-e-Surkh in post-stroke-disability: an open labeled, pre-post analysis
- Ascorbic acid improves extrapyramidal syndromes and corpus striatal degeneration induced by dopamine-2 receptor inhibition in Wistar rats
- Rutin ameliorates scopolamine-induced learning and memory impairments through enhancement of antioxidant defense system and cholinergic signaling
- Adansonia digitata L. leaf extract attenuates lead-induced cortical histoarchitectural changes and oxidative stress in the prefrontal cortex of adult male Wistar rats
