Neurotrophine-3 may contribute to neuronal differentiation of mesenchymal stem cells through the activation of the bone morphogenetic protein pathway

References

1. Chen, Y., Zeng, X., Zhang, K., Lai, B., Ling, E. and Zeng, Y. Neurotrophin-3 stimulates migration of mesenchymal stem cells overexpressing TrkC. Curr. Med. Chem. 20 (2013) 3022-3033.Search in Google Scholar

2. Zhang, W., Yan, Q., Zeng, Y.S., Zhang, X.B., Xiong, Y., Wang, J.M., Chen, S.J., Li, Y., Bruce, I.C. and Wu, W. Implantation of adult bone marrow-derived mesenchymal stem cells transfected with the neurotrophin-3 gene and pretreated with retinoic acid in completely transected spinal cord. Brain Res. 1359 (2010) 256-271.Search in Google Scholar

3. Schwab, J.M., Brechtel, K., Mueller, C.A., Failli, V., Kaps, H.P., Tuli, S.K. and Schluesener, H.J. Experimental strategies to promote spinal cord regeneration-an integrative perspective. Prog. Neurobiol. 78 (2006) 91-116.Search in Google Scholar

4. Choi, J.S., Leem, J.W., Lee, K.H., Kim, S.S., Suh-Kim, H., Jung, S.J., Kim, U.J. and Lee, B.H. Effects of human mesenchymal stem cell transplantation combined with polymer on functional recovery following spinal cord hemisection in rats. Korean J. Physiol. Pharmacol. 16 (2012) 405-411.Search in Google Scholar

5. Zhang, W., Zeng, Y.S., Zhang, X.B., Wang, J.M., Zhang, W. and Chen, S.J. Combination of adenoviral vector-mediated neurotrophin-3 gene transfer and retinoic acid promotes adult bone marrow cells to differentiate into neuronal phenotypes. Neurosci. Lett. 408 (2006) 98-103.Search in Google Scholar

6. Zhang, Y.Q., He, L.M., Xing, B., Zeng, X., Zeng, C.G., Zhang, W., Quan, D.P. and Zeng, Y.S. Neurotrophin-3 gene-modified Schwann cells promote TrkC gene-modified mesenchymal stem cells to differentiate into neuron-like cells in poly (lactic-acid-co-glycolic acid) multiple-channel conduit. Cells Tissues Organs 195 (2011) 313-322.Search in Google Scholar

7. Ding, Y., Yan, Q., Ruan, J.W., Zhang, Y.Q., Li, W.J., Zeng, X., Huang, S.F., Zhang, Y.J., Wu, J.L. and Fisher, D. Electroacupuncture promotes the differentiation of transplanted bone marrow mesenchymal stem cells overexpressing TrkC into neuron-like cells in transected spinal cord of rats. Cell Transplant. 22 (2013) 65-86.Search in Google Scholar

8. Jiang, Y., Jahagirdar, B.N., Reinhardt, R.L., Schwartz, R.E., Keene, C.D., Ortiz-Gonzalez, X.R., Reyes, M., Lenvik, T., Lund, T. and Blackstad, M. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418 (2002) 41-49.Search in Google Scholar

9. Oswald, J., Boxberger, S., Jørgensen, B., Feldmann, S., Ehninger, G., Bornhäuser, M. and Werner, C. Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells 22 (2004) 377-384.Search in Google Scholar

10. Pittenger, M.F., Mackay, A.M., Beck, S.C., Jaiswal, R.K., Douglas, R., Mosca, J.D., Moorman, M.A., Simonetti, D.W., Craig, S. and Marshak, D.R. Multilineage potential of adult human mesenchymal stem cells. Science 284 (1999) 143-147.Search in Google Scholar

11. Foudah, D., Redondo, J., Caldara, C., Carini, F., Tredici, G. and Miloso, M. Human mesenchymal stem cells express neuronal markers after osteogenic and adipogenic differentiation. Cell. Mol. Biol. Lett. 18 (2013) 163-186.Search in Google Scholar

12. Qian, L. and Saltzman, W.M. Improving the expansion and neuronal differentiation of mesenchymal stem cells through culture surface modification. Biomaterials 25 (2004) 1331-1337.Search in Google Scholar

13. Lescaudron, L., Naveilhan, P. and Neveu, I. The use of stem cells in regenerative medicine for Parkinson’s and Huntington’s diseases. Curr. Med. Chem. 19 (2012) 6018-6035.Search in Google Scholar

14. Chopp, M., Zhang, X.H., Li, Y., Wang, L., Chen, J., Lu, D., Lu, M. and Rosenblum, M. Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation. Neuroreport 11 (2000) 3001-3005.Search in Google Scholar

15. Hofstetter, C., Schwarz, E., Hess, D., Widenfalk, J., El Manira, A., Prockop, D.J. and Olson, L. Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery. P. Natl. Acad. SCI. 99 (2002) 2199-2204. Search in Google Scholar

16. Yazdani, S.O., Pedram, M., Hafizi, M., Kabiri, M., Soleimani, M., Dehghan, M.-M., Jahanzad, I., Gheisari, Y. and Hashemi, S.M. A comparison between neurally induced bone marrow derived mesenchymal stem cells and olfactory ensheathing glial cells to repair spinal cord injuries in rat. Tissue Cell 44 (2012) 205-213.Search in Google Scholar

17. Zurita, M. and Vaquero, J. Functional recovery in chronic paraplegia after bone marrow stromal cells transplantation. Neuroreport 15 (2004) 1105-1108.Search in Google Scholar

18. Ankeny, D.P., McTigue, D.M. and Jakeman, L.B. Bone marrow transplants provide tissue protection and directional guidance for axons after contusive spinal cord injury in rats. Exp. Neurol. 190 (2004) 17-31.Search in Google Scholar

19. Himes, B.T., Neuhuber, B., Coleman, C., Kushner, R., Swanger, S.A., Kopen, G.C., Wagner, J., Shumsky, J.S. and Fischer, I. Recovery of function following grafting of human bone marrow-derived stromal cells into the injured spinal cord. Neurorehabil. Neural. Repair. 20 (2006) 278-296.Search in Google Scholar

20. Neuhuber, B., Timothy Himes, B., Shumsky, J.S., Gallo, G. and Fischer, I. Axon growth and recovery of function supported by human bone marrow stromal cells in the injured spinal cord exhibit donor variations. Brain Res. 1035 (2005) 73-85.Search in Google Scholar

21. Guo, J., Zeng, Y., Li, H., Huang, W., Liu, R., Li, X., Ding, Y., Wu, L. and Cai, D. Cotransplant of neural stem cells and NT-3 gene modified Schwann cells promote the recovery of transected spinal cord injury. Spinal Cord 45 (2007) 15-24.Search in Google Scholar

22. Bregman, B., Broude, E., McAtee, M. and Kelley, M. Transplants and neurotrophic factors prevent atrophy of mature CNS neurons after spinal cord injury. Exp. Neurol. 149 (1998) 13-27.Search in Google Scholar

23. Bamber, N.I., Li, H., Lu, X., Oudega, M., Aebischer, P. and Xu, X.M. Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels. Eur. J. Neurosci. 13 (2001) 257-268.Search in Google Scholar

24. Bradbury, E.J., King, V.R., Simmons, L.J., Priestley, J.V. and McMahon, S.B. NT-3, but not BDNF, prevents atrophy and death of axotomized spinal cord projection neurons. Eur. J. Neurosci. 10 (1998) 3058-3068.Search in Google Scholar

25. Grill, R., Murai, K., Blesch, A., Gage, F. and Tuszynski, M. Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. J. Neurosci. 17 (1997) 5560-5572.Search in Google Scholar

26. Novikova, L.N., Novikov, L.N. and Kellerth, J.O. Survival effects of BDNF and NT-3 on axotomized rubrospinal neurons depend on the temporal pattern of neurotrophin administration. Eur. J. Neurosci. 12 (2000) 776-780.Search in Google Scholar

27. Zhang, Y., Dijkhuizen, P.A., Anderson, P.N., Lieberman, A.R. and Verhaagen, J. NT-3 delivered by an adenoviral vector induces injured dorsal root axons to regenerate into the spinal cord of adult rats. J. Neurosci. Res. 54 (1998) 554-562. Search in Google Scholar

28. Hapner, S.J., Boeshore, K.L., Large, T.H. and Lefcort, F. Neural differentiation promoted by truncated trkC receptors in collaboration with p75(NTR). Dev. Biol. 201 (1998) 90-100.Search in Google Scholar

29. Chalazonitis, A., D'Autréaux, F., Guha, U., Pham, T.D., Faure, C., Chen, J.J., Roman, D., Kan, L., Rothman, T.P. and Kessler, J.A. Bone morphogenetic protein-2 and-4 limit the number of enteric neurons but promote development of a TrkC-expressing neurotrophin-3-dependent subset. J. Neurosci. 24 (2004) 4266-4282.Search in Google Scholar

30. Sieber, C., Kopf, J., Hiepen, C. and Knaus, P. Recent advances in BMP receptor signaling. Cytokine Growth Factor Rev. 20 (2009) 343-355.Search in Google Scholar

31. Tropel, P., Noel, D., Platet, N., Legrand, P., Benabid, A.L. and Berger, F. Isolation and characterisation of mesenchymal stem cells from adult mouse bone marrow. Exp. Cell. Res. 295 (2004) 395-406.Search in Google Scholar

32. Gong, M., Bi, Y., Jiang, W., Zhang, Y., Chen, L., Hou, N., Chen, J. and Li, T. Retinoic acid receptor beta mediates all-trans retinoic acid facilitation of mesenchymal stem cells neuronal differentiation. Int. J. Biochem. Cell B. 45 (2013) 866-875.Search in Google Scholar

33. Ye, L., Fan, Z., Yu, B., Chang, J., Al Hezaimi, K., Zhou, X., Park, N.H. and Wang, C.Y. Histone demethylases KDM4B and KDM6B promotes osteogenic differentiation of human MSCs. Cell Stem Cell 11 (2012) 50-61.Search in Google Scholar

34. Paik, S., Jung, H.S., Lee, S., Yoon, D.S., Park, M.S. and Lee, J.W. miR-449a regulates the chondrogenesis of human mesenchymal stem cells through direct targeting of lymphoid enhancer-binding factor-1. Stem Cells Dev. 21 (2012) 3298-3308.Search in Google Scholar

35. Tiaden, A.N., Breiden, M., Mirsaidi, A., Weber, F.A., Bahrenberg, G., Glanz, S., Cinelli, P., Ehrmann, M. and Richards, P.J. Human serine protease HTRA1 positively regulates osteogenesis of human bone marrowderived mesenchymal stem cells and mineralization of differentiating boneforming cells through the modulation of extracellular matrix protein. Stem Cells 30 (2012) 2271-2282.Search in Google Scholar

36. Mezey, E., Chandross, K.J., Harta, G., Maki, R.A. and McKercher, S.R. Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science 290 (2000) 1779-1782.Search in Google Scholar

37. Brazelton, T.R., Rossi, F.M., Keshet, G.I. and Blau, H.M. From marrow to brain: expression of neuronal phenotypes in adult mice. Science 290 (2000) 1775-1779.Search in Google Scholar

38. Kopen, G.C., Prockop, D.J. and Phinney, D.G. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc. Natl. Acad. Sci. USA 96 (1999) 10711-10716.Search in Google Scholar

39. Chao, M.X, Rajagopal, R. and Lee, F.X. Neurotrophin signalling in health and disease. Clin. Sci. 110 (2006) 167-173.Search in Google Scholar

40. Bibel, M. and Barde, Y.A. Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. Genes Dev. 14 (2000) 2919-2937. Search in Google Scholar

41. Blesch, A., Lu, P. and Tuszynski, M.H. Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair. Brain Res. Bull. 57 (2002) 833-838.Search in Google Scholar

42. Spitzer, N.C. Electrical activity in early neuronal development. Nature 444 (2006) 707-712.Search in Google Scholar

43. Hung, S.C., Cheng, H., Pan, C.Y., Tsai, M.J., Kao, L.S. and Ma, H.L. In vitro differentiation of size-sieved stem cells into electrically active neural cells. Stem Cells 20 (2002) 522-529. Search in Google Scholar