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Compendium of Targets of the Top 100 Commercially Important Drugs

Published/Copyright: September 1, 2009
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Chemistry International -- Newsmagazine for IUPAC
From the journal Chemistry International -- Newsmagazine for IUPAC Volume 27 Issue 1

The Project Place|Information about new, current, and complete IUPAC projects and related initiatives

See also www.iupac.org/projects

Compendium of Targets of the Top 100 Commercially Important Drugs

Published articles on drug discovery frequently point out that most commercially successful pharmaceutical agents act on a relatively small number of molecular targets. However, there does not appear to be a resource where compiled target information is readily available in a single location.

The goal of this project is to provide a resource containing the following information on the targets of the most commercially important drugs: type of target (enzyme, receptor, etc.); brief description of relevance to disease or indication; reference to knockout information, if available; reference to structural information, if available; listing of the marketed drugs that interact with the target along with potency and relevant selectivity information. It is anticipated that this compendium will be a valuable teaching and reference source for the drug discovery community.

For more information, contact the Task Group Chairman, John Proudfoot <jproudfo@rdg.boehringer-ingelheim.com>.

www.iupac.org/projects/2004/2004-025-1-700.html

Published Online: 2009-09-01
Published in Print: 2005-01

© 2014 by Walter de Gruyter GmbH & Co.

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  25. Photochemistry
  26. Polymers and Organic Chemistry
  27. Solubility Phenomena
  28. Chemistry in Africa
  29. Heteroatom Chemistry
  30. Physical Organic Chemistry
  31. Biological Polyesters
  32. Nanotechnology
  33. Nuclear Analytical Methods
  34. Macromolecules
  35. Carotenoids
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https://doi.org/10.1515/ci.2005.27.1.19b

Articles in the same Issue

  1. From the Editor
  2. Contents
  3. Did You Say the IUPAC Conference?
  4. Scientists and Archeologists are Working to Preserve the Coatings on China’s 2 200-Year-Old Terracotta Army
  5. Properties and Processing of Qi-Lacquer
  6. On Scientoons, and Other Light-Hearted Mind-Benders that Help Us Appreciate Chemistry
  7. IUPAC Division VI Takes Stock and Looks Ahead
  8. Element 111 is Named Roentgenium
  9. From Macro to Poly
  10. Young Chemists to the 40th IUPAC Congress
  11. Simples and Compounds: A Proposal
  12. Heat Capacity of Liquids: Critical Review and Recommended Values for Liquids with Data Published Between 2000 and 2004
  13. Compendium of Targets of the Top 100 Commercially Important Drugs
  14. Critically Evaluated Propagation Rate Coefficients for Free-Radical Polymerization of Water-Soluble Monomers Polymerized in the Aqueous Phase
  15. Capacity Building in the Mathematical Sciences
  16. Nomenclature of Cyclic Peptides
  17. Nomenclature of Organic Chemistry
  18. Properties and Units in the Clinical Laboratory Sciences. Part XVIII. Properties and Units in Clinical Molecular Biology (IUPAC Technical Report)
  19. Compilation of k0 and Related Data for NAA in the Form of Electronic Database (IUPAC Technical Report)
  20. Ionic Polymerization
  21. Polymers
  22. Green Chemistry in Russia
  23. Radioactivity, Ionizing Radiation, and Nuclear Energy
  24. Coordination and Organometallic Chemistry of Germanium, Tin, and Lead
  25. Photochemistry
  26. Polymers and Organic Chemistry
  27. Solubility Phenomena
  28. Chemistry in Africa
  29. Heteroatom Chemistry
  30. Physical Organic Chemistry
  31. Biological Polyesters
  32. Nanotechnology
  33. Nuclear Analytical Methods
  34. Macromolecules
  35. Carotenoids
  36. Learning Science
  37. Molten Salts, Chemistry, and Technology
  38. Boron Chemistry
  39. Polymers for Advanced Technologies
  40. Recent Advances in Food Analysis
  41. Mark Your Calendar
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