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Prognostic significance of smudge cell percentage in chronic lymphocytic leukemia. Facts or artifacts? Methodological considerations and literature review
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Antonio La Gioia
, Paolo Chiarugi
, Enrico Michelucci
, Francesca Aquila
Published/Copyright:
August 29, 2022
Received: 2022-07-08
Accepted: 2022-08-22
Published Online: 2022-08-29
Published in Print: 2022-10-26
© 2022 Walter de Gruyter GmbH, Berlin/Boston
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Keywords for this article
chronic lymphocytic leukemia;
Gumprecht shadows;
peripheral blood microscopic review;
smudge cells prognostic value
Articles in the same Issue
- Frontmatter
- Editorial
- Measuring FGF23 in clinical practice: dream or reality?
- Reviews
- Fibroblast growth factor 23: translating analytical improvement into clinical effectiveness for tertiary prevention in chronic kidney disease
- Pursuing appropriateness of laboratory tests: a 15-year experience in an academic medical institution
- General Clinical Chemistry and Laboratory Medicine
- Moving average quality control of routine chemistry and hematology parameters – a toolbox for implementation
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- Total bilirubin assay differences may cause inconsistent treatment decisions in neonatal hyperbilirubinaemia
- Early predictors of abnormal MRI patterns in asphyxiated infants: S100B protein urine levels
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- Analytical evaluation and bioclinical validation of new aldosterone and renin immunoassays
- Improving clinical performance of urine sediment analysis by implementation of intelligent verification criteria
- Clinical evaluation of the OC-Sensor Pledia calprotectin assay
- Serous body fluid evaluation using the new automated haematology analyser Mindray BC-6800Plus
- Analysis of cryoproteins with a focus on cryofibrinogen: a study on 103 patients
- Reference Values and Biological Variations
- Within-subject biological variation estimates using an indirect data mining strategy. Spanish multicenter pilot study (BiVaBiDa)
- Short-term biological variation of serum glial fibrillary acidic protein
- Reference ranges for GDF-15, and risk factors associated with GDF-15, in a large general population cohort
- Serum GFAP – reference interval and preanalytical properties in Danish adults
- Determination of pediatric reference limits for 10 commonly measured autoantibodies
- Hematology and Coagulation
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- Infectious Diseases
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- Letters to the Editor
- Thyroid stimulating hormone: biased estimate of allowable bias
- Letter to the Editor relating to Clin Chem Lab Med 2022;60(9):1365–72
- Reply to the Letter of Sun et al. [1] relating to Clin Chem Lab Med 2022;60(9):1365–72
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- Reporting magnesium critical results: clinical impact on pregnant women and neonates
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- 54th National Congress of the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC – Laboratory Medicine)