Use of quality indicators to compare point-of-care testing errors in a neonatal unit and errors in a STAT central laboratory
-
Miguel Cantero
,
Maximino Redondo
Abstract
Background: Point-of-care testing (POCT), like other laboratory tests, can be affected by errors throughout the total testing process. To evaluate quality error rates, the use of quality indicators (QIs) is recommended; however, little information is available on the quality error rate associated with POCT. The objective of this study was to investigate quality error rates related to POCT and compare them with central laboratory (CL) testing.
Methods: We studied standardized QIs for POCT in comparison to CL testing. We compared error rates related to requests, collection, and handling of samples and results from external quality assessment program (EQAP) and internal quality control (IQC).
Results: The highest difference between POCT and CL testing was observed for QI related to patient identification, 45.3% vs. 0.02% (p<0.001). Regarding specimen collection and handling, the QI related to samples without results was also higher in POCT than in CL testing, 15.8% vs. 3.3% (p<0.001). For the QI related to insufficient sample volume, we obtained 2.9% vs. 0.9% (p=0.27). Unlike QIs for the preanalytical phase, QIs for the analytical phase had better results in POCT than CL testing. We obtained 8.3% vs. 16.6% (p=0.13) for QI related to unacceptable results in EQAP and 0.8% vs. 22.5% (p<0.001) for QI related to unacceptable results in IQC.
Conclusions: Our results show that the preanalytical phase remains the main problem in POCT like in CL testing and that monitoring of quality indicators is a very valuable tool in reducing errors in POCT.
Acknowledgments
We thank to M. Lucía Alcalde Lorenzo for providing language help.
Author contributions
All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Financial support: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
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©2015 by De Gruyter
Artikel in diesem Heft
- Frontmatter
- Editorials
- The new and the old of heparin-induced thrombocytopenia
- Biological variation – reliable data is essential
- Biological variation: back to basics
- Review
- Influence of educational, audit and feedback, system based, and incentive and penalty interventions to reduce laboratory test utilization: a systematic review
- Opinion Papers
- Recent guidelines and recommendations for laboratory assessment of the direct oral anticoagulants (DOACs): is there consensus?
- Meeting report: present state of molecular genetics in clinical laboratories. Report on the VII European Symposium on Clinical Laboratory and In Vitro Diagnostic Industry in Barcelona
- Genetics and Molecular Diagnostics
- Non-invasive prenatal diagnosis of monogenic disorders: an optimized protocol using MEMO qPCR with miniSTR as internal control
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- General Clinical Chemistry and Laboratory Medicine
- Preanalytical errors: a preliminary approach to the point of view of primary health care givers
- Comparison of Improvacuter™ tubes with BD Vacutainer™ tubes for various hormones in the aspects of stability and influence of gel separators
- Use of quality indicators to compare point-of-care testing errors in a neonatal unit and errors in a STAT central laboratory
- Serological features of antibodies to protamine inducing thrombocytopenia and thrombosis
- Comparison of three different immunoassays in the diagnosis of heparin-induced thrombocytopenia
- How the direct oral anticoagulant apixaban affects hemostatic parameters. Results of a multicenter multiplatform study
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- Biological variation database: structure and criteria used for generation and update
- Cardiovascular Diseases
- The tumor necrosis factor-α –238G/A and IL-6 –572G/C gene polymorphisms and the risk of idiopathic dilated cardiomyopathy: a meta-analysis of 25 studies including 9493 cases and 13,971 controls
- Diabetes
- Multicentre evaluation of the Premier Hb9210 HbA1c analyser
- Infectious Diseases
- Determination of quality control limits for serological infectious disease testing using historical data
- Corrigendum
- Enrichment and enumeration of circulating tumor cells by efficient depletion of leukocyte fractions
- Letters to the Editors
- Influence of age and gender on red blood cell distribution width
- Effect of exhaustive running exercise on red blood cell distribution width
- Clinically useful samples and reference change value
- Loss of retinol stability in patient samples
- Evaluation of a new thyroglobulin sensitive assay in patients with differentiated thyroid cancer
- Caution in a case of highly discrepant carbohydrate antigen 19-9 values in an apparently healthy patient taking spirulina: a case report
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Artikel in diesem Heft
- Frontmatter
- Editorials
- The new and the old of heparin-induced thrombocytopenia
- Biological variation – reliable data is essential
- Biological variation: back to basics
- Review
- Influence of educational, audit and feedback, system based, and incentive and penalty interventions to reduce laboratory test utilization: a systematic review
- Opinion Papers
- Recent guidelines and recommendations for laboratory assessment of the direct oral anticoagulants (DOACs): is there consensus?
- Meeting report: present state of molecular genetics in clinical laboratories. Report on the VII European Symposium on Clinical Laboratory and In Vitro Diagnostic Industry in Barcelona
- Genetics and Molecular Diagnostics
- Non-invasive prenatal diagnosis of monogenic disorders: an optimized protocol using MEMO qPCR with miniSTR as internal control
- A novel biosensor-based microarray assay for the visualized detection of CYP2C19 ∗2, ∗3, ∗4 and ∗5 polymorphisms
- General Clinical Chemistry and Laboratory Medicine
- Preanalytical errors: a preliminary approach to the point of view of primary health care givers
- Comparison of Improvacuter™ tubes with BD Vacutainer™ tubes for various hormones in the aspects of stability and influence of gel separators
- Use of quality indicators to compare point-of-care testing errors in a neonatal unit and errors in a STAT central laboratory
- Serological features of antibodies to protamine inducing thrombocytopenia and thrombosis
- Comparison of three different immunoassays in the diagnosis of heparin-induced thrombocytopenia
- How the direct oral anticoagulant apixaban affects hemostatic parameters. Results of a multicenter multiplatform study
- Auto-validation of complete blood counts in an outpatient’s regional laboratory
- Performance evaluation of the digital cell imaging analyzer DI-60 integrated into the fully automated Sysmex XN hematology analyzer system
- Circulating keratan sulfate as a marker of metabolic changes of cartilage proteoglycan in juvenile idiopathic arthritis; influence of growth factors as well as proteolytic and prooxidative agents on aggrecan alterations
- Reference Values and Biological Variations
- Biological variation database: structure and criteria used for generation and update
- Cardiovascular Diseases
- The tumor necrosis factor-α –238G/A and IL-6 –572G/C gene polymorphisms and the risk of idiopathic dilated cardiomyopathy: a meta-analysis of 25 studies including 9493 cases and 13,971 controls
- Diabetes
- Multicentre evaluation of the Premier Hb9210 HbA1c analyser
- Infectious Diseases
- Determination of quality control limits for serological infectious disease testing using historical data
- Corrigendum
- Enrichment and enumeration of circulating tumor cells by efficient depletion of leukocyte fractions
- Letters to the Editors
- Influence of age and gender on red blood cell distribution width
- Effect of exhaustive running exercise on red blood cell distribution width
- Clinically useful samples and reference change value
- Loss of retinol stability in patient samples
- Evaluation of a new thyroglobulin sensitive assay in patients with differentiated thyroid cancer
- Caution in a case of highly discrepant carbohydrate antigen 19-9 values in an apparently healthy patient taking spirulina: a case report
- Influence of vitamin K antagonist treatment on activated partial thromboplastin time
- Evaluation of the diagnostic characteristics of urinary kidney injury molecule 1 (uKIM-1) and uKIM-1/creatinine ratio in the assessment of incipient diabetic kidney disease
